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Instructions

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Instruction for use: Bromergon

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Dosage form: tablets

Active substance: Amantadine*

ATX

N04BC01 Bromocriptine

Pharmacological groups:

Dopaminomimetics

Anti-Parkinsonics

The nosological classification (ICD-10)

D35.2 Benign neoplasm of pituitary gland: Pituitary adenoma; Prolactinomas; Macro-prolaktinoma; Microprolactinoma; Prolactinoma; Somatoliberinoma; Aumada del Castillo Syndrome Tumors of the pituitary and suprasellar region

E22.0 Acromegaly and pituitary gigantism: Pituitary gigantism; Acromegaly; Dysfunction of growth hormone secretion

E22.1 Hyperprolactinaemia: Hyperprolactinemia medication; Hyperprolactinaemia with infertility; Hyperprolactinemia in men; Hyperproduction of prolactin; Idiopathic hyperprolactinemia; Chiari-Frommel Syndrome; Forbes-Albright Syndrome; Tumor galactorrhea; Argonsa del Castillo Syndrome; Forbes-Albright Syndrome

G21 Secondary Parkinsonism: Medicinal Parkinsonism; Parkinsonism; Parkinsonism symptomatic; Disorders of extrapyramidal system; Parkinson's Syndrome

N60.1 Diffuse cystic mastopathy: Benign cystic change in mammary glands; Cystic fibrosis mastopathy; Fibrous-cystic mastopathy; Pre-cancerous condition of mammary glands; Benign mammary gland disease; Benign breast tumor

N61 Inflammatory Diseases of the Breast: Mastitis; Purulent mastitis; Non-sprout mastitis; Postpartum mastitis; Mastitis

N91 Absence of menstruation, meager and rare menstruation: Amenorrhea; Amenorrhea hypogonadotropic; Amenorrhea is prolactin-dependent; Oligomenorrhoea; Shortening of the secretory phase of the menstrual cycle; Menstrual disorders; Menstruation disorders; Prolactin-dependent amenorrhea without galactorrhea

N94.3 Premenstrual tension syndrome: Pronounced premenstrual syndrome; Menstrual psychosomatic disorder; Menstrual syndrome; Premenstrual tension; Premenstrual status; Premenstrual period; Premenstrual syndrome; Menstruation syndrome

N97 Female infertility: Female infertility in anovulation; Hyperprolactinemic infertility; Hyperprolactinaemia with infertility; Endocrine infertility; Infertility due to hypothalamic-pituitary dysfunction; Infertility infertility; Infertility; Infertility on the background of hyperprolactinaemia; Functional infertility; Marriage is infertile; Infertility of ovarian genesis; Stimulation of the growth of a single follicle

O92.6 Galactorrhea: Chiari-Frommel Syndrome; Idiopathic galactorrhea

Composition and release form

1 tablet contains bromocriptine mesylate 2.5 or 10 mg; In bottles of 30 pcs., In a cardboard box 1 bottle.

Pharmachologic effect

Mode of action - antiparkinsonian, dopaminomimetic.

Influences the metabolism of dopamine and norepinephrine in the CNS, reduces release of serotonin, reduces blood levels of catecholamines. It inhibits the secretion of the hormones of the anterior lobe of the pituitary gland, especially prolactin and somatotropin.

Clinical Pharmacology

Oppresses uterine contractions, dilates blood vessels. Reduces tremors, stiffness, akinesia and posture disorder in parkinsonism.

Indications for the Bromergon

Hyperprolactinemia with infertility, amenorrhea, galactorrhea, or impairment in the luteal phase of the ovarian cycle; Galactorrhea with normal prolactin in the blood; Fibrocystic mastopathy; Postpartum and non-prenatal mastitis; Mastopathy; premenstrual syndrome; Prolactinoma; acromegaly; Parkinsonism.

Contraindications

Hypersensitivity (including to ergot alkaloids), uncontrolled arterial hypertension, pregnancy.

Side effects

Nasal congestion, nausea, vomiting, constipation, dyspepsia, orthostatic hypotension, fatigue, sleepiness, cold vasoconstriction, impaired bladder function vasospasms fingers in patients with Parkinson's with high doses - agitation, mental disorders (hallucinations, mental confusion, psychotic , Paranoid and manic states), dyskinesia.

Interaction

Alcohol and other drugs that depress the central nervous system increase the effect of the drug on psychophysical abilities.

Dosing and Administration

Inside, during a meal - 2.5 mg 2-3 times a day for several months (giperlaktinemiya, infertility, galactorrhea, breast, postpartum, neposlerodovoy mastitis), when the cyclic and non-cyclic mastitis - 2.5 mg 2 times day during ovulation, PMS - 2.5 mg 2 times a day from 14th day of the menstrual cycle until the onset of menstruation; in acromegaly and prolaktinome - 5-10 mg 2 times a day (up to 60 mg per day), Parkinsonism (in ineffectiveness combination "levodopa + carbidopa") initial dose - 1.25 mg in the evening, then - 2.5 mg 2 times per day with gradual increase in the dose to 30-100 mg daily (in combination with a "levodopa + carbidopa" mean dose - 15-30 mg per day).

Precautionary measures

It is not recommended to work that requires concentration, vehicle management and work with mechanisms.

Storage conditions of the drug Bromergon

In the dark place at a temperature of no higher than 25 į C.

Keep out of the reach of children.

Shelf life of the drug Bromergon

3 years.

Do not use after the expiry date printed on the package.

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