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Instruction for use: Alprazolam

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Dosage form: substance-powder; tablets

Active substance: Alprazolam*


N05BA12 Alprazolam

Pharmacological group:

Anxiolytic agent (tranquilizer) [Anxiolytics]

The nosological classification (ICD-10)

F41.0 Panic disorder [episodic paroxysmal anxiety]: Panic state; Panic attack; Panic; Panic disorder

F41.2 Mixed anxiety and depressive disorder: Depression with anxiety-depressive components; Mixed anxiety-depressive conditions; Anxiety Depression; Anxious and depressing mood; Anxiety-depressive state; Anxious-depressive conditions; Anxiety-depressive syndrome; Anxious-Neurotic Conditions

F41.9 Anxiety disorder, unspecified: Neurotic disorders with anxiety syndrome; Severe anxiety; Neuro-like symptomatology; Neuro-like disorders; Neuro-like conditions; Neuroses with anxiety symptoms; Neuroses with a sense of anxiety; Acute situational and stress anxiety; Acute attack of anxiety; Severe Anxiety; Situational Anxiety Disorder; State of anxiety; Anxious and delusional component; Alarming state; Anxiety; Anxiety Disorders; Anxiety syndrome; Sense of anxiety; Alarm conditions; Chronic neurotic anxiety; Susto; Psychopathy with a predominance of anxiety and anxiety; Anxiety disorders in neurotic and neurosis-like states; Anxious neuroses; Anxious and delusional state; Acute situational stress alarm; Depressed mood with elements of anxiety

F48.9 Neurotic disorder, unspecified: Neurosis; Secondary neurotic symptom; Other neurotic conditions; Neurosis with increased irritability; Neuroses; Neuroses of all kinds; Neuroses with retardation; Neuroses of the heart; Neurotic disorders in alcoholism; Neurotic disorders with retardation; Neurotic disorders with anxiety syndrome; Neurotic reactions; Neurotic symptoms with alcoholism; Neurotic states; Neurotic syndrome; Neurotic disorder; Attack of neurological dysfunction; School neurosis; Emotional Stress


Tablets - 1 table.

active substance: Alprazolam 0.25 / 1 mg

Auxiliary substances: lactose monohydrate (sugar milk) - 91,95 / 137,4 mg; Potato starch - 5 / 7.5 mg; Povidone low molecular weight (PVP low molecular weight medical 12600 ħ 2700) - 1.8 / 2.6 mg; Magnesium stearate monohydrate (magnesium stearic acid) - 1 / 1.5 mg

Pharmachologic effect

Mode of action - anxiolytic.

Dosing and Administration

Inside, 2-3 times a day, regardless of food intake. Doses are selected depending on the severity of the syndrome, the individual sensitivity of the patient and his reaction to the drug. Begin the use of the drug with minimal doses (0.25-0.5 mg / day), followed by an increase first in the evening and then in the daytime for several days or weeks. Elderly and debilitated patients are prescribed 0.25 mg 2-3 times a day. Further increase in the dose to 0.5-0.75 mg / day is carried out with caution for good tolerability of the drug.

When anxiety, anxiety, the initial daily dose is 0.75-1.5 mg and can be increased to 3-4.5 mg / day. In panic disorders and depressive conditions, the daily dose can reach 3-6 mg; The highest daily dose is 10 mg.

The course of treatment with alprazolam is from several days (in acute condition of fear) to 3 months. The cessation of treatment should be carried out within 2-6 weeks, reducing the daily dose by no more than 500 micrograms every 3 days, in order to prevent the development of withdrawal syndrome (a sharp cessation of therapy can cause worsening anxiety and fear), sometimes even slower cancellation may be required.

Release form

Tablets, 0.25 mg and 1 mg. In the planar cell pack 10 tab. Or in a can of lightproof glass 50 table. 5 contour mesh packages or 1 jar are placed in a cardboard box.

Terms of leave from pharmacies

On prescription.

Storage conditions of the drug Alprazolam

In the dark place at a temperature of no higher than 30 ° C. List III of the list of narcotic drugs, psychotropic substances and their precursors subject to control in the Russian Federation.

Keep out of the reach of children.

Shelf life of the drug Alprazolam

5 years.

Do not use after the expiry date printed on the package.

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