Instruction for use: ProroxanI want this, give me price
Trade name of the drug – pirroxan, Pirroxan pills 0.015 g, Proroxan
The Latin name of the substance Proroxan
Proroxanum (genus. Proroxani)
Chemical rational name: 1- (2,3-Dihydro-1,4-benzdioksin-6-yl) -3- (3-phenyl-1-pyrrolidinyl) -1-propanone (as hydrochloride)
Gross formula C21H23NO3
Pharmacotherapeutic group: Alpha-blockers
The nosological classification (ICD-10)
F10.3 abstinence: Alcohol withdrawal syndrome; abstinence symptom; Abstinence syndrome in alcoholism; abstinence; alcohol Abstinence; alcohol withdrawal; Alcohol abstinence; Alcohol withdrawal syndrome; postabstinentnom disorder; postabstinentnom state; alcohol withdrawal syndrome; withdrawal syndrome; The syndrome of alcohol abstinence; alcohol withdrawal syndrome; Status of abstinence
F11 Mental and behavioral disorders due to use of opioids: Dependence on opioids; Opiate withdrawal; heroin addiction; heroin addiction; Diagnosis of opioid dependence; morphine withdrawal; morphine withdrawal; opium addiction; Opium withdrawal; Opioid dependence; Opioid addiction; Behavioral disorder and postabstinentnom for drug dependence
H81.0 Meniere's disease: Meniere's syndrome/ disease; Meniere's disease; Meniere's syndrome; Labyrinth dropsy; endolymphatic hydrops
I10 Essential (primary) hypertension: hypertension; Arterial hypertension; Arterial hypertension crisis course; Essential Hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Essential hypertension; Primary hypertension; Arterial hypertension, complications of diabetes; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; arterial Hypertension; malignant Hypertension; Hypertonic disease; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; Isolated systolic hypertension
I15 Secondary hypertension: Arterial hypertension, complications of diabetes; hypertension; The sudden increase in blood pressure; Hypertensive disorders of blood circulation; hypertensive condition; hypertensive crises; hypertension; arterial Hypertension; malignant Hypertension; hypertensive crises; accelerated hypertension; malignant hypertension; The aggravation of hypertensive disease; Transient hypertension; hypertension; Arterial hypertension; Arterial hypertension crisis course; renovascular hypertension; Hypertension symptomatic; Renal hypertension; Renovascular hypertension; renovascular hypertension; Symptomatic hypertension
L20 Atopic dermatitis: Itchy atopic eczema; common neurodermatitis; Allergic diseases of the skin; Allergic skin disease noninfectious etiology; Allergic skin disease etiology nemikrobnoy; Allergic skin diseases; Allergic skin lesions; Allergic reactions on the skin; atopic dermatitis; Allergic dermatosis; Allergic diathesis; Allergic itching dermatosis; Allergic skin disease; Allergic skin irritation; allergic Dermatitis; atopic Dermatitis; allergic dermatoses; exudative diathesis; Allergic skin disease; Cutaneous allergic reaction to drugs and chemicals; Cutaneous reactions to medications; Skin and allergic disease; Acute eczema; Chronic atopic dermatitis; Exudative diathesis; Itchy allergic dermatosis
T75.3Motion sickness when moving: motion Sickness; air Sickness; seasickness; kinetoses; Airsickness; Seasickness; kinesia; The symptom of motion sickness; kinetoses; motion sickness syndrome
CAS code 33743-96-3
Description of Proroxan
White or yellowish white crystalline powder. It is soluble in water and alcohol.
Pharmacological Properties of Proroxan
Pharmachologic effect - Mode of action - antiabstinentnoe, hypotensive, antipruritic, sedative.
Blocks postsynaptic alpha 1 and presynaptic alpha2-adrenergic receptors. It has peripheral and central influence. Adrenergic vasoconstrictor, decreases transmission pulse, eliminates spasms and expands peripheral vessels, especially the arterioles and precapillaries. It suppresses the excitability of brain diencephalic structures and adjusts tone simpatoadrenalovoj system.
Indications for Proroxan
Hypertensive crisis, diencephalic crisis sympathoadrenal type, Meniere's syndrome, sea and air sickness, cravings (morphine and alcohol), anxiety-depressive syndrome, allergic dermatoses.
Contraindications for Proroxan
Severe forms of atherosclerosis, coronary heart disease, cerebrovascular accidents, circulatory insufficiency II-III stage breast age (up to 6 months).
Side effect of Proroxan
Bradycardia, hypotension, increased anginal pain.
Overdose of Proroxan
Symptoms: bradycardia, orthostatic collapse, a sharp decrease in blood pressure.
Treatment: maintaining vital functions (phenylephrine, ephedrine, koronarolitiki et al.).
Action intensifies neuroleptics (phenothiazines, butyrophenone, difenilbutilpiperidina, thioxanthenes). Against the background of procainamide may decrease stroke volume.
Routes of administration
Inside, intramusculary, subdermal.
Precautions for substance Proroxan
Caution should be used in elderly patients. It is recommended to monitor blood glucose levels (possible increase in the level of endogenous insulin).