DR. DOPING

Instructions

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Instructions / Instruction for use: Zyncet

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Dosage form: syrup; Film Coated Tablets

Active substance: Cetirizine

ATX

R06AE07 Cetirizine

Pharmacological groups:

H1-antihistamines

The nosological classification (ICD-10)

H10.1 Acute atopic conjunctivitis: Allergic conjunctivitis; Allergic eye diseases; Allergic conjunctivitis; Allergic conjunctivitis caused by chemical and physical factors; Allergic rhinoconjunctivitis; Allergic inflammation of the eyes; Spring Qatar; Spring keratitis; Spring conjunctivitis; Conjunctivitis allergic; Year-round allergic conjunctivitis; Exacerbation of pollinosis in the form of rhinoconjunctival syndrome; Acute allergic keratoconjunctivitis; Acute allergic conjunctivitis; Superficial bacterial infection of the eyes; Rhinoconjunctivitis; Seasonal allergic conjunctivitis; Seasonal conjunctivitis; SENSORY; Chronic allergic keratoconjunctivitis; Chronic allergic conjunctivitis

J30 Vasomotor and allergic rhinitis: Allergic rhinopathy; Allergic rhinosinusopathy; Allergic diseases of the upper respiratory tract; Allergic rhinitis; Allergic rhinitis seasonal; Vasomotor runny nose; Prolonged allergic rhinitis; All-year-round allergic rhinitis; All-year allergic rhinitis; Year-round or seasonal allergic rhinitis; All-the-year-round rhinitis of an allergic nature; Rhinitis vasomotor allergic; Exacerbation of pollinosis in the form of rhinoconjunctival syndrome; Acute allergic rhinitis; Edema of the nasal mucosa; Edema of the nasal mucosa; Edema of the mucous membrane of the nasal cavity; Swelling of the nasal mucosa; Swelling of the nasal mucosa; Pollinosis; Permanent allergic rhinitis; Rhinoconjunctivitis; Rhinosinusitis; Rhinosinusopathy; Seasonal allergic rhinitis; Seasonal allergic rhinitis; Hay rhinitis; Chronic allergic rhinitis; Allergic diseases of the respiratory tract

J30.1 Allergic rhinitis caused by pollen of plants: Hay fever; Hay fungus; hay fever; Hypersensitivity to pollen of plants; Polyposis allergic rhinosinusitis; Seasonal pollinosis; Seasonal rhinitis

L29 Itching: Itching with partial obstruction of the biliary tract; Dermatitis itchy; Dermatosis with persistent itching; Other itching dermatoses; Itching dermatoses; Itching allergic dermatosis; Itching dermatitis; Itching dermatosis; Itching itch; Excruciating itching; Severe itching; Endogenous itching; Skin itching with dermatosis; Restricted itchy dermatitis; Itching of the skin; Itchy scalp; Itching eczema

L50.0 Allergic urticaria: Skin reaction to medication

L50.1 Idiopathic urticaria: Idiopathic urticarial; Chronic idiopathic urticarial

L50.8 Other urticaria

R21 Rash and other nonspecific skin rashes: Skin rash; Skin and mucous eruptions; Skin rashes; Drug rash; Medicinal rash fixed; Dry skin rashes; Rash; Toxidermy; Toxicoderma; Toxic rash; Korepodobnye rashes from drugs; Macular Papular Eruptions; Drug-induced rash

Composition and release form

Tablets, coated with a film membrane 1 tab.

Cetirizine hydrochloride 10 mg

Auxiliary substances: lactose; corn starch; Povidone; Magnesium stearate; Eudragit; Macrogol 6000; Titanium dioxide; Talcum purified; acetone; Isopropyl alcohol; Dichloromethane; purified water

In the blister 10 pcs .; In a pack of cardboard 1 blister.

Syrup 5 ml

Cetirizine hydrochloride 5 mg

Auxiliary substances: propylhydroxybenzoate; Methylhydroxybenzoate; Anhydrous sodium salt of acetic acid; Glacial acetic acid; glycerol; Sucrose; Banana flavoring; purified water

In bottles of dark glass of 60 ml, complete with a measuring cup; In a pack of cardboard 1 bottle.

Description of dosage form

Tablets: oblong, biconcave, white, film-coated, with a risk on one side.

Syrup: a clear, colorless or light yellow slightly viscous liquid.

Pharmachologic effect

Mode of action - anti-allergic, antihistamine.

The active substance of the drug, cetirizine, belongs to the group of competitive histamine antagonists, it blocks histamine H1 receptors. Cetirizine influences the histamine-dependent stage of allergic reactions, and also reduces the migration of eosinophils, restricts the release of inflammatory mediators at the cellular stage of the allergic reaction. It prevents development and facilitates the course of allergic reactions, has antipruritic effect, has almost no anticholinergic and antiserotonin action. In therapeutic doses, it practically does not have a sedative effect.

Indication of the Zyncet

Symptomatic treatment of allergic rhinitis and conjunctivitis (including year-round and seasonal), hay fever (hay fever), idiopathic urticaria and other allergic dermatoses, accompanied by itching and rashes.

Contraindications

Hypersensitivity to cetirizine, other constituents of the drug, hydroxyzine.

Application in pregnancy and breastfeeding

It is not recommended to prescribe during pregnancy and breastfeeding.

Side effects

Usually the drug is well tolerated. In some cases, headache, drowsiness, dizziness, agitation, dry mouth; Disorders of the gastrointestinal tract: dyspepsia, abdominal pain, flatulence. As an exception, there may be signs of hypersensitivity to the drug (hives, swelling, dyspnea). In this case, the drug should be discontinued immediately and urgently needed to see a doctor. It is necessary to inform the doctor about all side effects.

Interaction

It is not recommended to combine the use of Zyncet with other drugs without consulting a doctor. With simultaneous administration with bronchodilators, containing theophylline as an active substance, an increase in the incidence of side effects of Zyncet. Data on the interaction of cetirizine with alcohol have not been obtained to date. Despite this, the use of alcoholic beverages when treated with Zyncet is not recommended.

Dosing and Administration

Inside, swallowing whole, washed down with a small amount of water, regardless of the time of food intake.

The drug Zyncet is used according to the doctor's prescription (to avoid complications).

Children from 2 to 6 years: 2.5 mg (1/2 tsp syrup) 2 times a day or 5 mg (1 tsp) once a day; From 6 to 12 years: 10 mg (1 table or 2 tsp syrup) once a day or 5 mg (1/2 table or 1 tsp syrup) 2 times a day, in the morning and in the evening; Adults and children over 12 years: 10 mg (1 table or 2 teaspoons of syrup) once a day.

The elderly or patients with severe impairment of liver and / or kidney function are prescribed by the doctor individually, in a reduced dose.

If you miss the time of taking the drug, the next dose should be taken as soon as possible. In the event that the time of the next administration of the drug is approaching, the next dose should be taken on schedule, without increasing the total dose.

Overdose

Symptoms (when taking the drug in a dose of more than 5 tablets): signs of intoxication in the form of drowsiness; In children - anxiety, increased irritability, there may be signs of anticholinergic action in the form of urine retention, dry mouth, constipation.

Treatment: the drug should be stopped, cleaned of the stomach, take activated charcoal, immediately consult a doctor.

Special instructions

Care should be taken when prescribing the drug to persons who perform activities requiring high rates of mental and physical reactions (eg vehicle management, machine maintenance, altitude work, etc.), patients with impaired liver and / or kidney function, and elderly people .

Storage conditions of the drug Zyncet

In a dry place, at a temperature of no higher than 30 ° C.

Keep out of the reach of children.

Shelf life of the drug Zyncet

Film-coated tablets 10 mg - 3 years.

Syrup 5 mg / ml - 2 years.

Do not use after the expiry date printed on the package.


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