Instructions / Instruction for use: Tamoxifen HEXALI want this, give me price
Active substance Tamoxifen
ATX code L02BA01 Tamoxifen
Estrogens, gestagens; Their homologues and antagonists
Antineoplastic hormonal agents and hormone antagonists
Nosological classification (ICD-10)
C50 Malignant neoplasm of breast
Cancer of the nipple and areola of the breast, Breast carcinoma, The hormone-dependent form of recurrent breast cancer in women in menopause, Hormone-dependent breast cancer, Disseminated breast carcinoma, Disseminated Breast Cancer, Malignant breast cancer, Malignant neoplasm of breast, Contralateral breast cancer, Locally advanced or metastatic breast cancer,Locally-distributed breast cancer, Locally-recurring breast cancer, Metastatic breast carcinoma, Metastasis of breast tumors, Metastatic breast carcinoma, Inoperable breast carcinoma, Incompatible breast cancer, Breast cancer in women with metastases, Breast cancer in men with metastases, Breast Cancer, Breast cancer in men, Mammary cancer, Breast cancer with distant metastases, Breast cancer in postmenopausal women, Breast cancer hormone-dependent, Breast cancer with local metastases, Breast cancer with metastases, Breast cancer with regional metastases,Breast cancer with metastases, Common hormone-dependent forms of breast cancer, Common Breast Cancer, Recurrent Breast Cancer, Recurrence of breast tumors, Breast cancer, Estrogen-dependent breast cancer, Estrogen-Dependent Breast Cancer, Disseminated breast cancer with overexpression of HER2, Tumors of the mammary glands
Composition and form of release
Tablets, coated with a coating.
Tamoxifen (as citrate) 10 mg / 20 mg / 30 mg / 40 mg
In a planar cell pack of 10; In a box of 3 or 10 packages.
Pharmacological action - antitumor, cytostatic, antiestrogenic.
Competitive (instead of the endogenous ligand) binds estrogen receptors in target organs by blocking formation estrogenretseptornogo complex.
Metastatic breast carcinoma, adjuvant therapy after surgical treatment of breast carcinoma.
pregnancy and lactation
Contraindicated in pregnancy (before treatment, pregnancy should be excluded). During treatment, reliable contraception should be provided.
Pain in the bones and foci of tumor growth, nausea, vomiting, flushing, menstrual suppression in premenopausal, itching in the genital area, vaginal bleeding, swelling, anemia, ovarian cysts, phlebitis, thrombosis, blurred vision, skin rash.
Mutual weakening of the effect with estrogens. When concomitant administration with drugs that lower blood clotting may potentiate anticoagulation (increased risk of bleeding).
Dosing and Administration
Inside. Usually prescribed 20-40 mg daily. With prolonged therapy, taking 30 mg daily is recommended.
It should be particularly careful with thrombocytopenia, leukopenia and hypercalcemia (mandatory control of blood calcium, and platelets).
At a temperature not exceeding 25 ° C.
Keep out of the reach of children.
Do not use after the expiry date printed on the package.