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DR. DOPING

Instructions

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Instruction for use: Panadol soluble

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Active substance Paracetamol

ņ“’ N02BE01 Paracetamol

Pharmacological group

Anilides

Nosological classification (ICD-10)

G43 Migraine

The pain of migraine, Migraine, hemiplegic migraine, Migraine headache, A migraine attack, Continuous headache, hemicranias

K13.7 Other and unspecified lesions of oral mucosa

Aspirin burn of the oral mucosa, Gum pain when wearing dentures, Inflammation of the mouth, Inflammation of the oral mucosa, Inflammation of the oral mucosa after radiation therapy, Inflammation of the oral mucosa after chemotherapy, Inflammation of the oral mucosa, Inflammation of the mucous membranes of the mouth, Inflammatory diseases of the oral cavity, Inflammatory process of pharynx, Disease of the oral mucosa, Injuries to the oral cavity and larynx, Injuries of the oral mucosa, Trophic diseases of the oral mucosa, Erosive-ulcerative periodontal disease, Erosive-ulcerative lesion of the oral mucosa, Erotic mucous membrane of the oral cavity, Erotic-ulcerative periodontal lesions, Erotic-ulcerative lesions of the oral mucosa, Radio-epileleitis, Irritation from dental prostheses, Irritation of the oral mucosa with dentures and braces, Oral cavity, When wearing dentures

M25.5 Pain in the joint

Arthralgia, Pain syndrome in musculo-articular diseases, Pain syndrome in osteoarthritis, Pain syndrome in osteoarthritis, Pain syndrome in acute inflammatory diseases of the musculoskeletal system, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Pain in the joints, Soreness of the joints, Soreness of joints in severe physical exertion, Painful inflammatory joint damage, Painful conditions of the musculoskeletal system, Painful joint conditions, Painful traumatic affection of joints, Pain in the musculoskeletal system, Pain in Shoulder Joints, Pain in the joints, Joint pain, Joint pain with injuries, Musculoskeletal pain, Pain with osteoarthritis, Pain in the pathology of the joints, Pain in rheumatoid arthritis, Pain in chronic degenerative bone diseases, Pain in chronic degenerative joint diseases, Bone-joint pain, Joint pain, Arthritic pain of rheumatic origin, Articular pain syndrome, Joint pain, Rheumatic pain, Rheumatic pains

M54.3 Sciatica

Ishialgia, Neuralgia of the sciatic nerve, Sciatic neuritis

M79.1 Myalgia

Myofascial pain syndromes ,Pain syndrome in musculo-articular diseases, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Pain in the muscles, Tenderness of muscles, Muscular soreness in severe physical exertion, Painful conditions of the musculoskeletal system, Pain in the musculoskeletal system, Pain in the muscles, Pain at rest, Muscle aches, Muscle pain, Musculoskeletal pain, Myalgia, Muscle pain, Muscle pain at rest, Muscle pain, Muscular pain of non-rheumatic origin, Muscle pain of rheumatic origin, Acute muscle pain, Rheumatic pain, Rheumatic pains, Myofascial syndrome, Fibromyalgia

M79.2 Neurology and neuritis, unspecified

Pain syndrome with neuralgia, Brachialgia, Occipital and intercostal neuralgia, Neuralgia, Neuralgic pain, Neuralgia, Neuralgia of intercostal nerves,Neuralgia of the posterior tibial nerve, Neuritis, Neuritis traumatic, Neuritis, Neurological Pain Syndromes, Neurological contractures with spasms, Acute neuritis, Peripheral neuritis,Post-traumatic neuralgia,Severe pain of a neurogenic nature, Chronic neuritis, Essential neuralgia

N94.6 Dysmenorrhea Unspecified

Pain during menstruation, Functional disorders of the menstrual cycle, Menstrual cramps, Emmeniopathy, Pain during menstruation, Painful menstrual irregularities, algomenorrhea, algomenoreya, Pain smooth muscle spasm, Pain spasm of smooth muscles (renal and biliary colic, intestinal spasms, dysmenorrhea), Pain spasm of smooth muscles of internal organs (kidney and biliary colic, intestinal spasms, dysmenorrhea), Disalgomenoreya, dysmenorrhea, Dysmenorrhea (essential) (Exfoliative), menstrual disorder, menstruation painful, metrorrhagia, Violation of the menstrual cycle, Menstrual irregularities, Prolaktinzavisimoe menstrual disorders, Prolaktinzavisimoe menstrual dysfunction, Pain spasm of smooth muscles of internal organs, Spasmodic dysmenorrhea, Primary disalgomenoreya

R50 Fever of unknown origin

Malignant hyperthermia, Hyperthermia malignant

R51 Headache

Pain in the head, Cephalgia, Pain with sinusitis, Pain in the back of the head, Painful headache, Headache of vasomotor genesis, Headache of vasomotor origin, Headache with vasomotor disorders, Headache, Neurological headache, Serial headache

R52 Pain, not elsewhere classified

Pain syndrome of radicular origin, Pain syndrome of small and medium intensity of different genesis, Pain syndrome after orthopedic surgery, Pain syndrome in superficial pathological processes, Radicular pain in the background of osteochondrosis of the spine, Radicular pain syndrome, Pleural pain, Chronic pain

R52.2 Other constant pain

Pain syndrome, rheumatic origin, Pain at vertebral lesions, Pain in the chamber, Pain for burns, Pain syndrome weak or moderate, Perioperative pain,Moderate to severe pain, Moderately or weakly expressed pain syndrome, Moderate to severe pain, Ear pain of otitis, Neuropathic pain, neuropathic pain

Composition and form of release

1 tablet, coated, contains paracetamol 500 mg; 12 pcs. in the blister, 1 blister in the box.

1 tablet soluble - 500 mg; in a laminated strip of 2 pcs., in a box of 6 strips.

pharmachologic effect

Pharmacological action - antipyretic, analgesic.

Suppresses the synthesis of PG in the central nervous system, reduces the excitability of the hypothalamic center of heat regulation, increases heat transfer.

Pharmacodynamics

Possesses analgesic and antipyretic properties; the latter are manifested in conditions of febrile syndrome of any genesis.

Pharmacokinetics

Quickly and almost completely absorbed from the digestive tract. The concentration in the plasma reaches a peak after 30-60 min, T1 / 2 plasma - 1-4 hours Metabolized in the liver. It is excreted in the urine, mainly in the form of esters with glucuronic and sulfuric acids; less than 5% is displayed unchanged.

Indications

Pains of weak and moderate intensity (headache, migraine, back pain, arthralgia, myalgia, neuralgia, toothache, menalgia). Feverish syndrome with colds.

Contraindications

Hypersensitivity.

Side effects

Allergic reactions in the form of skin rashes.

Interaction

Enhances the effect of indirect anticoagulants (coumarin derivatives). Metoclopramide or domperidone is increased, and cholestyramine reduces the rate of absorption.

Dosing and Administration

Inside, adults - 2 tables. up to 4 times a day with an interval between doses not less than 4 hours (the maximum daily dose is 8 tablets), children from 6 to 12 years old - 1 / 2-1 table. up to 4 times a day with an interval between doses not less than 4 hours (the maximum daily dose is 4 tablets). Soluble tablets are dissolved in 1/2 cup of water before use.

Overdose

Symptoms of an overdose in the first 24 hours are pallor, nausea, vomiting and pain in the abdominal area. After 12-48 hours after administration, kidney and liver damage can occur with the development of hepatic insufficiency (encephalopathy, coma, death). Damage to the liver is possible with 10 g or more (in adults). Acute renal failure with tubular necrosis can develop and in the absence of serious liver damage. Other manifestations of an overdose are cardiac arrhythmias and pancreatitis. Treatment - taking methionine inside or / in the introduction of N-acetylcysteine.

Precautionary measures

It is not recommended to combine with other drugs, which include paracetamol, give children under 6 years. Caution should be exercised in cases of severe impairment of liver or kidney function. For the duration of treatment, alcohol intake should be avoided.

special instructions

The risk of overdose increases in patients with alcoholic liver diseases of a non-cirrhotic nature.

Storage conditions

At a temperature of no higher than 25 į C.

Keep out of the reach of children.

Shelf life

tablets, film-coated 500 mg - 5 years.

tablets, film-coated 500 mg - 5 years.

tablets, soluble 500 mg - 4 years.

Do not use after the expiry date printed on the package.

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