Instructions / Instruction for use: NavobanI want this, give me price
Dosage form: Capsules; Solution for intravenous administration; Injection
Active substance: Tropisetron*
Antiemetic means and preparations
The nosological classification (ICD-10)
R11 Nausea and vomiting: Postoperative vomiting; Nausea; Vomiting; Vomiting in the postoperative period; Vomiting medication; Vomiting in the background of radiation therapy; Vomiting uncontrollable; Vomiting in radiation therapy; Persistent vomiting; Indomitable vomiting; Postoperative nausea; Vomiting with chemotherapy; Vomiting of the central genesis; Vomiting with cytotoxic chemotherapy; Persistent hiccups; Repeated vomiting
Y43.1 Adverse reactions in the therapeutic use of antitumor antimetabolites: Treatment with mercaptopurine
Y43.2 Adverse reactions in the therapeutic use of antineoplastic natural preparations
Y43.3 Adverse reactions in the therapeutic use of other antitumor drugs
Composition and release form
1 ml of solution for injection contains troposisetron hydrochloride 1 mg; In ampoules of 2 and 5 ml.
1 capsule - 5 mg; In the package 5 pcs.
Mode of action - antiemetic.
Selectively blocks the excitation of presynaptic 5-HT3 receptors of peripheral neurons (takes part in the origin of the emetic reflex) and CNS (mediates the influence of the vagus nerve on the area postrema).
The duration of action is 24 hours, which allows you to apply 1 time per day.
Indications for the Navoban
Nausea and vomiting with antitumor therapy (prevention and treatment) and in the postoperative period.
Hypersensitivity, children's age (up to 2 years).
Application in pregnancy and breastfeeding
In pregnancy, it is contraindicated, except in cases where the purpose of an operation is to interrupt an early pregnancy. Lactating women should stop breastfeeding.
Abdominal pain, constipation, diarrhea, headache, dizziness, weakness, fainting, circulatory shock, cardiac arrest; Allergic reactions.
Dosing and Administration
To prevent nausea and vomiting caused by antitumor therapy, appoint courses for 6 days. The daily dose for adults is 5 mg. The first day (shortly before the start of chemotherapy) is administered iv, in the next 5 days - inside (1 capsule per day). Children older than 2 years - in a daily dose of 0.2 mg / kg, the maximum daily dose - up to 5 mg; The first day is administered iv, in the next 5 days - inside (the contents of the ampoule are mixed with orange juice or a drink of the cola type). For treatment and prevention of postoperative nausea and vomiting, adults are prescribed a dose of 2 mg IV.
Care should be taken with uncontrolled hypertension. Patients driving vehicles or working with potentially dangerous machines and mechanisms should consider that treatment reduces the reaction rate.
Storage conditions of the drug Navoban
At temperatures below 30 ° C (do not freeze).
Keep out of the reach of children.
Shelf life of the drug Navoban
Do not use after the expiry date printed on the package.