Instruction for use: MegaceI want this, give me price
Active substance Megestrol
ATX code G03DB02 Megestrol
Estrogens, gestagens; Their homologues and antagonists
Antineoplastic hormonal agents and hormone antagonists
Composition and form of release
1 tablet contains megestrol acetate 40 or 160 mg; In bottles of 100 pcs., In the box 1 bottle.
The pharmacological action is gestagenic, antitumoral.
Suppresses the production of estradiol and androstenedione by the adrenal glands, has a cytotoxic effect on hormone-sensitive cells of tumors and suppresses the liberalization of a number of factors of their growth. It blocks the formation of cachectin and interleukin-1 or their effect.
After oral administration, it is rapidly absorbed from the digestive tract. Cmax is achieved in 2-3 hours. T1 / 2 - 2-3 days. It is excreted in urine (57-78%) and with feces (8-30%).
Disseminated breast cancer, endometrial cancer, anorexia and cachexia in cancer patients and AIDS patients.
The first 4 months of pregnancy.
Bloody discharge from the vagina; Very rarely - fluid retention, thrombophlebitis, Itenko-Cushing syndrome (iatrogenic).
Dosing and Administration
Inside, once or in several (2-4) receptions. With disseminated breast cancer - 160 mg per day; With anorexia and cachexia in cancer patients and AIDS patients - 480 mg (and more) per day.
Do not use in pregnancy diagnosis. Cautiously appoint at a thrombophlebitis, even in the anamnesis. Megace does not exclude surgical, chemotherapeutic or radiotherapy for cancer.
At a temperature not exceeding 25 ° C. Avoid storage at temperatures above 40 ° C.
Keep out of the reach of children.
Do not use after the expiry date printed on the package.