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Instructions / Instruction for use: Lactoglobulinum contra bacteria morbifica conditionalia et salmonellas vaccum siccum

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Dosage form: Lyophilizate for solution for oral administration

Active substance: Lactoglobulin against bacteria morbifica conditionalia and salmonella

ATX

J06BC Other immunoglobulins

Pharmacological group

Immunoglobulins

The nosological classification (ICD-10)

A09 Diarrhea and gastroenteritis of allegedly infectious origin (dysentery, bacterial diarrhea): Bacterial diarrhea; Bacterial dysentery; Bacterial infections of the digestive tract; Bacterial gastroenteritis; Diarrhea bacterial; Diarrhea or dysentery of amoebic or mixed etiology; Diarrhea of infectious genesis; Diarrhea on the background of antibiotic therapy; Traveler's Diarrhea; Travelers diarrhea due to changes in diet and habitual diet; Diarrhea due to antibiotic therapy; Dysenteric bacteriocarrier; Dysenteric enteritis; Dysentery; Dysentery bacterial; Dysentery mixed; Gastrointestinal infection; GI tract infections; Infectious diarrhea; Infectious Disease of the GI tract; Infection of the gastrointestinal tract; Infection of the biliary tract and gastrointestinal tract; GI tract infection; Summer diarrhea; Nonspecific acute diarrhea of infectious nature; Nonspecific chronic diarrhea of infectious nature; Acute bacterial diarrhea; Acute diarrhea in food poisoning; Acute dysentery; Acute bacterial gastroenteritis; Acute gastroenterocolitis; Acute Enterocolitis; Subacute dysentery; Diarrhea chronic; Refractory diarrhea in AIDS patients; Staphylococcal enteritis in children; Staphylococcal enterocolitis; Toxic diarrhea; Chronic dysentery; Enteritis; Enteritis infectious; Enterocolitis

P78.8 Other specified disorders of the digestive system in the perinatal period: Congenital insufficiency of hepatic enzymes; Dysbacteriosis in newborns; Constipation in infants; Campylobacter gastroenteritis in newborns; Perforation of the stomach in newborns; Infarction of the intestines in newborns

Composition

Lyophilizate for oral solution preparation

Active substances:

Immunoglobulins of colostrum colostrum containing antibodies to group B (S. typhimurium) salmonella, group D (S.enteritidis and S. Dublin) salmonella, proteus (P.mirabilis and P.vulgaris), Klebsiella (K.pneumoniae) and pseudomonas (P .aeruginosa)

Description of dosage form

Sterile lyophilizate yellowish white, easily soluble in water, odorless.

Characteristic

The preparation is a purified fraction of the globulins of the immune cow colostrum obtained by the alcohol deposition method and lyophilized.

Pharmachologic effect

Mode of action - antibacterial.

Pharmacological (immunobiological) properties

The antibodies in the preparation have a pronounced antibacterial and antitoxic effect against Salmonella, Proteus, Klebsiella, and Pseudomonas.

Indications of the drug Lactoglobulinum contra bacteria morbifica conditionalia et salmonellas vaccum siccum

Treatment of children in the presence of diseases associated with diarrhea caused by group B salmonella (S. typhimurium), salmonella and group D (S.enteritidis and S. Dublin), proteus (P.mirabilis and P. vulgaris), klebsiella (K.pneumoniae ), Pseudomonas (P.aeruginosa), as well as associations of these microorganisms and dysbacterioses;

Prevention of salmonella infection in newborns and children at risk for the incidence of acute intestinal infections (early transfer to artificial or mixed feeding, the use of antibiotics and chemotherapy drugs, education in the homes of the child), incl. When in contact with diseased salmonella infection.

Contraindications

Individual intolerance to cow's milk.

Side effects

Reactions to the drug are not registered.

Interaction

Lactoglobulin is compatible with antibiotics and normoflora preparations.

Dosing and Administration

Inside, for 20-30 minutes before feeding.

From the bottle remove the metal cap and rubber stopper, pour boiled water at room temperature at a rate of 10 ml (2 ts.lokki) per dose of the drug, mix.

Do not shake the preparation.

Within 5 minutes after the addition of water, a clear, slightly opalescent liquid with a yellowish tinge should form.

If the content of the vial is 2 doses, the diluted drug, closed with a stopper, may be stored at a temperature of 2 to 10 ° C for not more than 1 day.

The preparation with the broken integrity of the package, without labeling, changing physical properties, in the presence of foreign inclusions, with improper storage, with expired shelf life is not suitable for use.

The drug is prescribed at the earliest possible time from the date of diagnosis: newborns - 1 dose 1-2 times a day, children from 1 to 6 months - 1 dose 2 times a day; From 6 months to 1 year - 2 doses 2 times a day; Children older than 1 year - 2 doses 2-3 times a day. The course of treatment is from 7 to 14 days. In severe cases, treatment can be extended to 21 days.

Treatment with lactoglobulin is carried out against the background of conventional antibacterial and symptomatic therapy.

To fix the effect of treatment is recommended combination of the drug with bifidumbacterin.

For the prevention of salmonella infection in children at risk from 1 month and older - 1 dose 2 times a day, 10 to 14 days. It is possible to repeat courses of using lactoglobulin at intervals of 3-4 months.

For emergency prevention of salmonella infection in contact with the sick, the newborn - 0.5 doses 2 times a day, children from 1 month and older - 1 dose 2 times a day, 10 days.

Release form

Lyophilizate for solution for oral administration. In vials of 1 dose (0.5 g) or 2 doses (1 g). The package contains 10 fl.

Manufacturer

FGUN "Rostov Research Institute of Microbiology and Parasitology" of Rospotrebnadzor

Conditions of supply of pharmacies

Without recipe.

Storage conditions of the drug Lactoglobulinum contra bacteria morbifica conditionalia et salmonellas vaccum siccum

In a dry, dark place at a temperature of 2-10 ° C.

Keep out of the reach of children.

The shelf life of the drug Lactoglobulinum contra bacteria morbifica conditionalia et salmonellas vaccum siccum

4 year.

Do not use beyond the expiration date printed on the package.

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