Instruction for use: Humulin M2 20/80

ATX Code A10AC01 Human insulin

Active substance Insulin biphasic [human biosynthetic]

Pharmacological group

Insulins

Nosological classification (ICD-10)Z31.1 Artificial insemination

E10 Insulin-dependent diabetes mellitus

Decompensation of carbohydrate metabolism, Diabetes mellitus, Diabetes insulin sugar, Diabetes mellitus type 1, Diabetic ketoacidosis, Insulin-dependent diabetes, Insulin-dependent diabetes mellitus, Coma hyperosmolar non-ketoacidotic, Labile form of diabetes mellitus, Violation of carbohydrate metabolism, Type 1 diabetes mellitus, Type I diabetes mellitus, Insulin-dependent diabetes mellitus, Type 1 diabetes mellitus

E11 Non-insulin-dependent diabetes mellitus

Acetonuric diabetes, Decompensation of carbohydrate metabolism, Diabetes insulin-independent sugar, Diabetes sugar type 2, Type 2 Diabetes, Non-insulin-dependent diabetes, Non-insulin dependent diabetes mellitus, Non-insulin-dependent diabetes mellitus, Insulin resistance, Insulin resistant diabetes mellitus, Coma lactobacillus diabetic, Violation of carbohydrate metabolism, Type 2 diabetes mellitus, Diabetes mellitus type II, Diabetes mellitus in adulthood, Diabetes mellitus in old age, Diabetes insulin-independent, Diabetes mellitus type 2, Sugar insulin-independent diabetes type II

Composition and form of release

The suspension for injection contains recombinant human insulin 40 and 100 IU / ml; In bottles of 10 ml, in cartridges of 1.5 or 3.0 ml for syringe handles such as Humapen and BD-Pen.

Characteristic

A sterile mixture of human insulin containing 20% soluble insulin and 80% isophane-protamine insulin.

pharmachologic effect

Pharmacological action - hypoglycemic.

Increases glucose uptake by tissues, inhibits glycogenolysis, stimulates the formation of glycogen.

Clinical Pharmacology

The effect develops in 30 minutes, reaches a maximum after 1.5-9 hours and lasts 14-16 hours.

indications

Diabetes mellitus type I and II.

Contraindications

Hypoglycemia.

Side effects

Lipodystrophy, insulin resistance, allergic reactions.

Dosing and Administration

V / m (intramuscularly), subcutaneously ; The dose is determined individually.

Storage conditions

In the refrigerator, at a temperature of 2-8 ° C (do not freeze).

Keep out of the reach of children.

Shelf life

2 years.

Do not use after the expiry date printed on the package.