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Pharmacological action - immunomodulatory, antiviral.
With preventive and therapeutic use, the drug has an immunomodulating and antiviral effect. Effectively and experimentally clinically established against influenza viruses, parainfluenza, herpes simplex viruses type 1 and type 2 (herpes simplex, genital herpes), other herpes viruses (chicken pox, infectious mononucleosis), enteroviruses, tick-borne encephalitis virus, rotavirus, coron , calicivirus, adenovirus, respiratory syncytial virus. It reduces the concentration of viruses in affected tissues, affects the system of endogenous interferons and their associated cytokines, and induces the formation of endogenous “early” interferons (IFN α / β) and gamma interferon (IFN-γ).
Stimulates the humoral and cellular immune response. Increases the production of antibodies (including secretory IgA), activates the functions of T-effectors, T-helpers (Tx), normalizes their ratio. Increases the functional reserve of Tx and other cells involved in the immune response. It is an inducer of a mixed Tx1- and Tx2-type immune response: it increases the production of Tx1 cytokines (IFN-γ, IL-2) and Tx2 (IL-4, -10), normalizes (modulates) the balance of Tx1 / Tx2 activity. Increases the functional activity of phagocytes and natural killer cells. It has antimutagenic properties.
The sensitivity of modern physicochemical methods of analysis (gas-liquid chromatography, high-performance liquid chromatography, chromatography-mass spectrometry) does not allow us to evaluate the content of the active components of the drug Anaferon in biological fluids, organs and tissues, which makes it technically impossible to study pharmacokinetics.
Indications of Anaferon:
·prevention and treatment of acute respiratory viral infections (including influenza);
·complex therapy of infections caused by herpes viruses (infectious mononucleosis, chicken pox, labial herpes, genital herpes);
·complex therapy and prevention of recurrence of chronic herpes virus infection, including labial and genital herpes;
·complex therapy and prevention of other acute and chronic viral infections caused by tick-borne encephalitis virus, enterovirus, rotavirus, coronavirus, calicivirus;
·the use of bacterial infections in the complex therapy;
·complex therapy of secondary immunodeficiency states of various etiologies, including prevention and treatment of complications of viral and bacterial infections.
Dosage and administration:
Inside, not during meals. Keep the tablet in your mouth until completely dissolved.
10 drops per reception (drops are dosed in a spoon). In the first day of treatment : the first 2 hours of 10 drops every 30 minutes , then, in the remaining time, 3 more times at regular intervals. From 2 to 5 days: 10 drops 3 times a day.
The drug is taken outside of meals. In the first day of treatment, the first five doses of the drug should be carried out in the interval between feedings or 15 minutes before feeding the child or taking fluids.
SARS, influenza, intestinal infections, herpes virus infections, neuroinfection, coronovirus. On the 1st day of treatment, 8 tablets are taken. according to the following scheme: 1 table. every 30 minutes in the first 2 hours (only 5 tablets for 2 hours), then 1 more tablet is taken during the same day. 3 times at regular intervals. On the 2nd day and then take 1 table. 3 times a day until complete recovery.
If there is no improvement on the 3rd day of treatment with ARVI and influenza, you should consult a doctor. In the epidemic season, for prophylactic purposes, the drug is taken daily 1 time per day for 1-3 months.
Genital herpes. In acute manifestations of genital herpes, take at regular intervals according to the following scheme: 1-3 days - 1 table. 8 times a day, then 1 table. 4 times a day for at least 3 weeks.
For the prevention of recurrence of chronic herpes virus infection - 1 table. in a day. The recommended duration of the preventive course is determined individually and can reach 6 months.
When using the drug for the treatment and prevention of immunodeficiency, in the complex treatment of bacterial infections - take 1 table. in a day.
If necessary, the drug can be combined with other antiviral and symptomatic agents.
No cases of overdose have been reported to date.
In case of accidental overdose, dyspeptic phenomena are possible due to excipients that are part of the drug.
The composition of the drug includes lactose monohydrate, and therefore it is not recommended for patients with congenital galactosemia, glucose malabsorption syndrome, or with congenital lactase deficiency.
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