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Genferon is a combined preparation, the action of which is due to the constituent components. Has a local and systemic effect.
Interferon alfa-2 has antiviral, antibacterial and immunomodulatory effects. Under the influence of interferon alpha-2, the activity of natural killers, T-helpers, phagocytes, as well as the intensity of differentiation of B-lymphocytes, increases in the body. Activation of leukocytes contained in all layers of the mucosa ensures their active participation in the elimination of primary pathological foci and provides recovery of secretory immunoglobulin A.
Interferon alfa-2 also directly inhibits the replication and transcription of viruses, chlamydia.
Taurine, which is part of the drug, has regenerative, reparative, membrane and hepatoprotective, antioxidant, anti-inflammatory properties.
Benzocaine is a local anesthetic. Reduces the permeability of cell membranes for sodium ions, displaces calcium ions from receptors located on the inner surface of the membrane, blocks the conduct of nerve impulses. Prevents the appearance of painful impulses in the endings of the sensory nerves and their conduction along nerve fibers.
Genferon is used in the complex therapy of infectious and inflammatory diseases of the urogenital tract in children and women, including pregnant women: genital herpes, chlamydia, ureaplasmosis, mycoplasmosis, recurrent vaginal candidiasis, gardnerellez, trichomoniasis, papillomavirus infection, bacterial vaginosis, cervical erosion, cervicitis , vulvovaginitis, bartholinitis, adnexitis, prostatitis, urethritis, balanitis, balanoposthitis.
Hypersensitivity to the components of the drug.
Candles of Genferon can be used both vaginally and rectally. The method of administration, dosage and duration of the course depend on the age, the specific clinical situation and are determined by the attending physician.
In adults and children over the age of 7, Genferon Light is used in a dosage of 250,000 IU of interferon alfa-2b for a suppository. In children under 7 years of age, it is safe to use the drug at a dosage of 125 000 IU of interferon alfa-2b per suppository.
With infectious and inflammatory diseases of the urogenital tract in women.
For 1 suppository (250,000 IU or 500,000 IU, depending on the severity of the disease) vaginally 2 times daily for 10 days. With prolonged forms 3 times a week every other day, one suppository for 1-3 months.
With a pronounced infectious inflammatory process in the vagina, it is possible to apply 1 suppository 500,000 IU intravaginally in the morning and 1 suppository 1,000,000 IU rectally at night while introducing a candle containing antibacterial / fungicidal agents into the vagina.
To normalize the indices of local immunity in the treatment of infectious and inflammatory diseases of the urogenital tract in women with a gestation period of 13-40 weeks, one suppository of 250,000 IU is administered vaginally 2 times daily for 10 days.
With infectious and inflammatory diseases in men.
Rectally, 1 suppository (500,000 IU or 1,000,000 IU, depending on the severity of the disease) 2 times a day for 10 days.
Allergic reactions: skin rash, itching. These phenomena are reversible and disappear after 72 hours after dose reduction or drug withdrawal.
With the introduction of the drug at a dose of 10 million IU / day, the risk of developing the following side effects increases:
From the side of the central nervous system: a headache.
From the hematopoietic system: leukopenia, thrombocytopenia.
Other: increased body temperature, increased sweating, fatigue, myalgia, loss of appetite, arthralgia.
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