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Original Jintropin rhGH

04 Apr 2017

What is the system for protecting the original Somatropin (rDNA origin) for injection from the underground?

GenSci Pharmaceuticals has developed a system to provide anti-counterfeit protection to protect the product from counterfeits. Its implementation allows not only to confirm the authenticity of the drug, but also to prevent the spread of falsified products.

Each package of Jintropin is assigned an individual number, designed to check the originality of the drug on the company's official website. Do not forget take Mildronate for better results.

When verifying the authenticity of the product it turns out whether the product you purchased was registered. Its implementation consists of several stages. First of all, you need to find on the site section: "Jintropin ™ Anti-counterfeiting System".

The packing box is equipped with a sticker on which the silver cover hides the original security code. After its removal, the code is entered into the cells that are on the site in the corresponding subsection.

Next, find a photo, the image on which is identical to the sticker on the packing box. If a match is found as a result of their comparison, you need to use the "same" button. This allows you to open a window with information confirming the belonging of this product to a particular market (country). This page contains a detailed description of the protection codes and photo gallery.

Somatropin (rDNA origin) for injection can be presented in 4 variants of packing depending on the number of bottles (5, 10, 20, 50) and additional equipment.


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How to increase your growth hormone?

04 Apr 2017

The information is provided for informational purposes, the administration does not recommend the use of unfamiliar drugs without the supervision of a doctor.

  • Clofelin (an antihypertensive drug) is a powerful secretion inductor from available pharmacological agents. It was experimentally proven that 0.3 mg of clonidine increases the level of GH from 0.2 to 5.4 ng / ml.,
  • GABA. You can also like Picamilon.
  • Protein intake
  • Moxonidine (hypotensive drug) - 0.3 mg raises the level from 0.1 to 4.8 ng / ml. In addition, moxonidine stimulates insulin secretion and has an anti-catabolic effect, which makes it a promising drug in bodybuilding.
  • Amino acid arginine
  • Amino acid glutamine
  • Baclofen is another stimulant with a proven effect. This drug is an analog of GABA, but unlike it, it has a good ability to penetrate the brain. In addition, it has a sedative, miorelaxing and euphoric effect.
  • Enough sleep
  • Physical exercises (the effect of aerobic exercise is almost 2 times higher than strength training)
  • Hunger (an inappropriate option in bodybuilding)
  • Creatine (it has recently been proven that creatine can increase the production of IGF-1)

Despite the fact that the effect of these additives and preparations is incomparable with the use of exogenous growth hormone, some of them can actually increase the production of growth hormone by 2-4 times with respect to the initial level.


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Regulation of Hormone Secretion

03 Apr 2017

One of the most important areas of the central nervous system, coordinating and controlling the functions of the endocrine glands, is the hypothalamus, where the neurosecretory nuclei and centers that participate in the regulation of the synthesis and secretion of the hormones of the adenohypophysis are localized. Hypothalamus is a region of the brain located between the cross of the optic nerves, the visual tract, the inner edge of the brain stem and papillae.


The hypothalamic groove running from the Sylvian aqueduct to the Monroeus opening separates the hypothalamus from the visual hillock. In the hypothalamus, three large zones are distinguished: periventricular, medial and lateral. In turn, each zone consists of several cores. Thus, in the periventricular zone one region and six nuclei are distinguished: the preoptic periventricular region, the anterior periventricular nucleus, the suprachiasmatic nucleus, the dorsomedial nucleus, the tubular magnocellular nucleus, the arcuate or arcuate nucleus (sometimes called the infundibular nucleus), the paraventricular periventricular nucleus.

In the middle zone of the hypothalamus, the medial preoptic region, the medial preoptic nucleus, the anterior hypothalamic region, the paraventricular nucleus, the ventromedial nucleus, the periphonal nucleus, the posterior hypothalamic region and the medial mamillary (papillary) core are distinguished. The lateral zone includes the lateral preoptic region, the lateral hypothalamic region and the supraoptic nucleus.

Experimental studies with the deactivation (destruction) of individual structures of the hypothalamus and the breakdown of its neural connections with other parts of the brain made it possible to establish that the nervous control of the anterior lobe of the pituitary gland is accomplished by two mechanisms (regulation levels).

The first level of regulation is realized by the so-called hypophysitropic region of the hypothalamus, which controls the initial (basal) secretion of the anterior lobe of the pituitary gland and neurohypophysis secretion. The second, higher level is provided by other hypothalamic and extrahypothalamic areas of the brain (hippocampus, anterior thalamus, middle brain, etc.) that participate in stimulation or inhibition of pituitary function.

The extrahypothalamic structures of the brain carry out an important neuroendocrine control of the pituitary gland and are responsible for the daily rhythm of hormone secretion. The middle brain, the hippocampus and the anteromedial thalamic nucleus are involved in the regulation of the secretion of ACTH, gonadotropins, prolactin, growth hormone. In addition, ascending afferent and direct connections from the reticular formation and the midbrain are projected into the hypothalamus, where dopaminergic and other cells secreting various monoamines are localized.

The hypothalamus has a rich network of blood vessels that form a portal system in the mid-elevation region. The most highly vascularized supraoptic and paraventricular nuclei. Histologically, the region of the middle elevation represents the contact zone containing the endings of numerous neurons localized in the listed hypothalamic nuclei, through which the secretion products of these neurons (hypophysotropic hormones) reach the capillaries of the portal (portal) pituitary system. Venous capillaries of the portal system have special openings (shunts), which make it possible to transfer compounds with sufficient molecular mass from the blood to the perivascular space of the medial elevation.

The hypothalamus, therefore, is the region that transforms information coming through the nerve pathways from the overlying parts of the nervous system, by changing the level of neurotransmitters (neurotransmitters), which include various monoamines: epinephrine, norepinephrine, dopamine, serotonin, acetylcholine, g-aminobutyric acid. Stressful situations and other factors lead to a change in the content, rate of synthesis and release of monoamines in the hypothalamus, which in turn change the rate of secretion of hypothalamic and hypophysotropic hormones, which leads to a corresponding change in the functional activity of the anterior lobe of the pituitary gland.

It is believed that neurotransmitters (monoamines) regulate the pituitary gland by several mechanisms: a) participation in the synaptic transmission of information coming from the limbic system of the brain to a neuron that produces hypophysitropic hormones (peptides); B) action on the membrane of the hypothalamic neuron and the process of releasing the pituitary hormone; C) a change in the functional activity of the axon of the hypothalamic neuron in the region of the capillaries of the portal (portal) pituitary system with the modification of hypophysitropic hormone transport into the blood; D) the influence on the cells of the anterior lobe of the pituitary gland with increasing or suppressing their secretory activity or modifying their response to the action of hypophysitropic hormones.

Thus, the hypothalamus is the place where the nerve and endocrine cells interact with each other, carrying out a fast and highly efficient transmission of information necessary for a quick response from the body, systems and the body as a whole with the purpose of providing vital activity to the body. The transfer of information from cell to cell is carried out by chemical messengers (hormones and monoamines) and electrical activity. Intercellular interactions, as recent studies have shown, can be accomplished by the following mechanisms: synaptic messenger transfer; Hormonal mechanism through circulating hormones; Paracrine mechanism, i.e. Without the hormone entering the blood, but only into the intercellular fluid; Autocrine mechanism, i.e. The release of the hormone from the cell into the intercellular fluid and the interaction of this hormone with the membrane receptors located on the same cell. It has been shown that norepinephrine, somatostatin, dopamine, gonadoliberin, oxytocin, vasopressin can act as hormones and be secreted by endocrine cells or neurons, and also found in synapses of nerve cells and act as neurotransmitters. Another group of hormones - glucagon, enkephalins, cholecystokinin, proiopiomelanocortin derivatives are secreted by endocrine cells, performing a hormonal function, and, being localized in the nerve endings, have a neurotransmitter effect. And these two properties are revealed in other hormones of the adenohypophysis. Tyroliberin and VIP are secreted by neurons, but they perform a hormonal function, and in the nerve endings they have an obvious neurotransmitter effect. You can also like Phenotropil.

The effect of the central nervous system on the hypothalamus is not only performed by the above-mentioned nervous mechanisms, but also by the transport of cerebrospinal fluid to various hormones, neurotransmitters and other substances (endorphins, enkephalins, substance P), which are produced in various areas of the central nervous system and the epiphysis. In the epiphysis, melatonin and a number of other indoles and polypeptides, modulating the function of the adrenals, thyroid and gonadal glands, are formed. Hormones of the epiphysis are released into the cerebrospinal fluid or the total blood flow and act in various ways. So, melatonin concentrates in the hypothalamus and the middle brain and affects the secretion of hypophysitropic hormones, changing the content of monoamines and neurotransmitters. Other epiphysis polypeptides act directly on the formation of hypophysotropic peptides.

It should be noted that, in addition to neurotransmitters, the mechanisms of the release of hypophysitropic hormones take the obligatory participation of the ions K + and Ca2 +, prostaglandins, cAMP and other substances.

The principle of feedback in the regulation of hormones:

Domestic scientist M.M. Zavadovsky, studying the patterns in the regulation of endocrine glands, first formulated the "plus-minus interaction" principle in 1933, which later became known as the "feedback principle".

By feedback is meant a system in which the end product of the activity of this system (for example, a hormone, a neurotransmitter and other substances) modifies or modifies the function of the components constituting the system aimed at changing the amount of the end product (hormone) or the activity of the system. Vital activity of the whole organism is a consequence of the functioning of numerous self-regulating systems (excretory, cardiovascular, digestive, respiratory, etc.), which in turn are controlled by the neuroendocrine-immune system.

All of the above represents, therefore, a complex of various self-regulating systems that are to a certain extent dependent and "subordinate". The end result or activity of the system can be modified in two ways, namely by stimulation to increase the amount of the final product (hormone) or enhance the activity of the effect, or by inhibiting the system to reduce the amount of the final product or activity. The first way of modifying is called positive, and the second - negative feedback.

An example of positive feedback is an increase in the level of the hormone in the blood that stimulates the release of another hormone (an increase in the level of estradiol in the blood causes LH release in the pituitary gland), and negative feedback when an elevated level of one hormone inhibits the secretion and release of the other (increasing the concentration of thyroid hormones in the blood Reduces the secretion of TSH in the pituitary gland). Hypothalamic-pituitary regulation is performed by mechanisms functioning on the principle of feedback, in which distinct levels of interaction are clearly distinguished.

By "long" feedback chain, it is understood that the peripheral endocrine gland interacts with the pituitary and hypothalamic centers (it is not excluded that with the suprahypothalamic and other areas of the central nervous system) by affecting the indicated centers of the changing concentration of hormones in the circulating blood. A "short" feedback loop is understood as such an interaction, when an increase in the pituitary tropic hormone (for example, ACTH) modulates and modifies the secretion and release of the pituitary hormone (in this case, corticoliberin).

The "ultrashort" feedback loop is a kind of interaction within the hypothalamus, when the release of one pituitary hormone affects the secretion and release of another pituitary hormone. This kind of feedback takes place in any endocrine gland. Thus, the release of oxytocin or vasopressin through the axons of these neurons and through intercellular interactions (from cell to cell) modifies the activity of neurons that produce these hormones. Another example, the release of prolactin and its diffusion into the intervascular spaces leads to an effect on neighboring lactotrophs, followed by inhibition of prolactin secretion.

The "long" and "short" feedback circuits function as systems of a "closed" type, i.e. Are self-regulating systems. However, they respond to internal and external signals, changing for a short time the principle of self-regulation (for example, under stress, etc.). Along with this, these systems are influenced by mechanisms that support the biological circadian rhythm associated with the change of day and night. Circadian rhythm is a component of the system that regulates the body's homeostasis and allows it to adapt to changing environmental conditions. Information about the rhythm of day-night is transmitted to the central nervous system from the retina of the eye to the suprachiasmatic nuclei, which together with the epiphysis form the central circadian mechanism - "biological clock". In addition to the mechanism of day-night, in the activities of these "hours" are involved other regulators.

Suprachiasmatic nuclei have an integrating role in maintaining biological rhythms. About 80% of the cells of the suprachiasmatic nuclei are excited by the action of acetylcholine. Attempts to change the rhythm of the activity of nuclei by the infusion of large amounts of serotonin, dopamine, tiroliberin, substance P, glycine or g-aminobutyric acid proved to be ineffective. However, some hormones (vasopressin, gonadoliberin, substance P) have been found in this area, which undoubtedly somehow participate in the mechanisms of maintaining biological rhythms.

The secretion of many hormones (ACTH, STG, glucocorticoids, etc.) is subject to significant fluctuations throughout the day. In Fig. 3 shows the daily rhythm of STH secretion. The study of circadian hormone secretion is of great clinical importance, since in some diseases (acromegaly, Itenko-Cushing's disease), the violation of the daily rhythm of hormone secretion is an important differential diagnostic feature that is used in the differentiation of syndromically similar pathology.


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Jintropin against Aging

02 Apr 2017

Ginotropin is a high-quality growth hormone, which today is the only remedy able to inhibit aging, as a process. And it's not just advertising headlines from covers of glossy magazines, somatotropin really allows you to look much younger than your years.

Both creams and lotions that contain antioxidants, for example, vitamins A, C, E, or fruit acids are able to smooth wrinkles, but they can not prevent their occurrence. A certain diet affects the healthy skin color, anaerobic and cardio workouts will help to keep the body normal, and antioxidants will free the body from the toxins that affect the occurrence of diseases.

The treatment with hormone estrogen or testosterone helps to restore many of the body's lost functions, but only therapy with Jintropin helps the body to rejuvenate itself without external influence.

Causes of skin aging.

In the process of aging, the body becomes unable to generate proteins under the skin, the proteins change, the skin becomes old in appearance. The main proteins of the skin - collagen and elastin, they form a cutaneous three-dimensional matrix structure, which for the skin - as an armature for sculpture from gypsum.

Over the years, as already mentioned, the generation of elastin and estrogen decreases. The structure of the proteins also changes. That is why the structure of the entire skin changes, deteriorating, in the irreversible process of aging and, in the end, dehydration occurs. Here when there are unpleasant wrinkles, and the structure of a skin obviously becomes any more that earlier.

People who use Gintropin for rejuvenation begin to look younger in the shortest possible time. Is this not an obvious reason to think about how quickly the body can start the regeneration process. Not only the composition of the skin changes (the synthesis of proteins increases, the subcutaneous matrix structure is restored), with the treatment of Jintropin, the regeneration process affects the entire body. This is not so strange, because every cell of the body tends to be renewed, including renewing bone, nervous and muscle tissue, so that they are strengthened by regeneration.

Among other things, the body begins to accelerate the metabolism, resulting in the burning of excess fatty tissue. Fatty tissue is reduced quantitatively throughout the body, and it is very important for curing obesity of internal organs - which is much more dangerous than ordinary obesity of people. As a result, treatment with Jintropin affects positively the whole body. All tissues are rejuvenated and regenerated, and this gives the effect of a person's recovery.

At the California Research Center, John Kentwell, MD, began using Gintropin in medical practice, adding Jintropine's positive influence to the already existing hormone replacement therapy for fifty-year-old gentlemen. Already in a short time - three months - men reduced the number of wrinkles, and the skin itself became more elastic and tightened to look. They looked so good and felt so much better that they simply refused further checks.
Tom Brocco, the host of the program on NBC dedicated to Jintropin, noted that the participants in his program look much higher than average and look very young. William B. William, a man of 80 years of age who participated in the program, played very polo in polo, and looked, according to the presenter, for all 55 years. Pauline McNair, 52 years old at that time, looked only forty. And really, if you look at these people, it was impossible at first glance to believe that they really are as old as they are in their passports. Younger than they looked not only because of the smoothed face skin, but also due to radiated energy and enthusiasm.
McNair, talking to twice the younger ladies on the air, looked no worse than them, although by her own admission, envied their youth. And the bodies of these elderly people also did not seem old. McNair's body in a bathing suit and the lower part of William's hip, obviously looked not old, covered with young and healthy skin.

Testing with a pinch

The most visually elastic skin demonstrates the so-called "pincher test." This happens when pulling the skin from the back of the palm and you can see how long it takes the skin to return to the opposite position. This is the easiest method to see how much your skin has grown old over the years, because the ability of the skin to take a starting position - this is the index of elasticity, or the marker of aging. Cheyn often stops people on the street and asks them to test with a pinch-pull the skin on the back of the hand and see how quickly she will return to her seat.
Prior to the application of Gintropin, says Chane, his skin returned to its place at the speed of an ordinary forty-year-old man. A year after Jintropine's treatment, he could already rival in this regard with 35-year-old people. Now, Cheyne can get around those who have not even reached the age of thirty.
In preparing this material, we talked with one 73-year-old man. He works as a carpenter and often his hands are in danger of injury. However, the treatment with Jintropin so condensed and allowed his skin to become rough, that now he does not experience that it is easy to touch to the blood. This is called a rebound of a young man. The most beautiful thing in this conversation was just to observe these young hands - elastic skin, lack of pigmentation and wrinkles. No one would have believed that those hands were over seventy.
Dr. Elmer Crenton, MD, head of the Mount Rayner Clinic in Yelme, Washington, has been treating people for more than five years with Jintropin. He himself has an unlimited amount of experience in the field of restoring the structure of the skin. He reports that thanks to the synthesis of protein, the skin becomes more elastic, getting collagen and elastin. And dehydration and dryness, which arise due to aging, disappear almost immediately during the treatment.
Thanks to the application of Jintropin, tissue repair is also taking place, although the effect does not manifest itself so quickly - sometimes this process takes up to several months. One of the patients who took Jintropin for two years, said that the scars that have arisen because of life under the hot sun of the tropical climate, disappeared. He felt that the texture of the skin just got better, not even counting the recovery.
Younger begin to look even brushes and soles. Pigmentary senile spots lose color, and sometimes even just disappear. The veins cease to be so obvious and convex, and the entire skin seems to accumulate moisture and acquire unprecedented elasticity. This means that the hands and feet, and all the skin on the body, undergo the process of rejuvenation, which will never give you even surgical intervention - lifting, and chemically enriched creams and ointments also will not help.

The body returns to moisture.The skin of the baby is most pleasant to the touch, ask anyone. It is soft, smooth, and you always want to touch it. This is due to the fact that most of the child's body is water, that's about ninety percent. After reaching adulthood, water loses its percentage in the body, it reaches sixty, and in old age we consist of only forty percent water. Aging is essentially dehydration and reduction of the processes of cell structure repair. The juicy young body slowly but surely turns into the old and wrinkled. Often this can be observed in young patients - usually this is due to a deficiency of growth hormones. These young people have problems with growth hormones, they have thin and dry skin, because of this they look much older than they really are.
Jintropin, being a growth hormone, obtained by the body from the external environment, makes the return of dried fruit to the stage of a ripe apple. This is due to a special effect, antinatriuretic effects, thanks to the kidneys, they keep sodium and water inside themselves. It is because of this effect and there are side effects of Gentropine - swelling, pain in the joint areas and carpal tunnel syndrome. It's all easy to eliminate if you reduce the dose of the drug or distribute it within 24 hours. Medicine is increasingly using growth hormone, and scientists are already finding the ideal dosage for each age, sex and effect, so that without side effects, restore youth and health of people.
And the hair grows.

Hair growth after taking growth hormones, Jinotropin also increases hair growth on the globe. Although scientists do not yet confirm this fact, there are remarks that hair improves its quality in the process of applying the drug. Of the 202 people who filled out the questionnaire offered by Terry and Cheyne, 38 percent said they had new hair. Elmer Crenton, for example, says that his hair began to grow faster and thicker, they start to shine and darken. He also claims that his grayed hair was now returning color. The fact that the hair is getting dark, reports a lot of other patients.
James Felts, for example, even said that new hair grows on the bald patches of his head. This is what he did not expect at all in his forties. One of those undergoing treatment with Dr. Baxas, who is called Jeffrey Clarkson, also says that the growth of hair on his head is increasing. Lord DiBenner also confirms the fact of hair growth, and also nails on the hands and feet. In addition, he notes that look nails and hair have become much better than before. This is confirmed by McNair, Pauline, who says that even her eyelashes are more dense. Jintropin has truly amazing effects on people!

Factors causing necrosis of skin cells.The growth, nutrition and recovery of cells directly depends on proteins and peptides, which are also growth factors. Gentropine allows these factors to be developed, and they, in turn, act restoratively on injured tissues, diseases and aging skin. Eric Dupont, Ph.D., head of the Eterna Laboratory in Quebec, says that growth hormone is like a marshal who leads growth factors that, in turn, do their business on individual parts of the tissues. Already often mentioned was an insulin-like growth factor-1, but it is not one that is an important factor. Many of these factors are concerned with restoring and maintaining the structure of the skin, one of them is the epidermal growth factor or EGF.

Simply put, the skin is both a mortal and immortal matter. Its upper layer, the epidermis, as it were, is immortal. Retinyl acid and other retinyls, as well as alpha hydrides, stimulate the epidermis to be immortal and on a daily basis help many people get rid of peeling on the skin. The dermis, which is located under the epidermal layer, is mortal. Dermis cells are divided only about a hundred times after conception. And the dermis is the main layer of the skin, which is affected by growth hormone.

Aging, the dermis thinens, loses elasticity and less growth factors, as well as cytokines (cell messengers), which usually give a signal to the skin cells, that they need to share. It is at such moments that Gintropin and the corresponding growth factors can stimulate the old cells to action, make them function on a par with young ones. A recent study has shown that fibroblast growth factor can stimulate even obsolete fibroblasts to produce elastin and collagen, which make up matrix proteins.

And therefore, fibroblasts stimulate the delivery of these proteins to the amount peculiar to many younger groups of ages. Thanks to these studies, it is obvious that very soon IGF1 and Gintropin will become the most popular means for tightening the skin of the face and will revolutionize the cosmetic world. The era of biochemical engineering is moving towards us.

Cosmetics and factors affecting the restoration of skin cells.
The best cosmetic products, such as creams and lotions, contain a combined amount of retinoic acid, alpha hydroxy acids, as well as antioxidants, like vitamin C and growth factors. Recently in the laboratory of the company Biosin was developed cosmetics, created by a new formula that uses peptides, as well as an extremely stable formula of vitamin C, to treat the skin that has suffered in the course of aging and from pigmented spots.
Vincent Giampapa, MD, is engaged in the study of many growth factors and other drugs. He does this at the National Skin Institute in Montclair, New Jersey. He explains his concept by the fact that during the research he and his team endow fibroblasts - skin cells with what is really necessary for their growth, reproduction and increase in the elasticity of the skin. The fibroblast DNA structure is restored, the amount of elastin and collagen increases.

To accelerate the process of cell division, they use, for example, RNA, which can help to restore the elasticity of the skin, hyaluronic acid that retains moisture and regenerates collagen, yeast cell extract or retinyl palmitate, which is very similar to vitamin C together with vitamin A. For use, RNA is taken from supplements that contain amino acids and nucleic acids, for example, Spiralin or AFA, which you can always purchase at a health food store. These are blue-green algae, some of which are marine, while the latter are freshwater algae. These sources are so rich in nucleic acids and also amino acids that are very important, that if swallowed, their concentration in the blood will increase immediately. Also, Jampap uses growth hormone releasers, for example, ornithine, lysine, arginine and glutamine.
In this type of treatment, Gintropin, being an analog of growth hormone, is the main ingredient because it speeds up the entry of amino acid and nucleic acid to where they can be used to renew and restore the cellular structure. In this mode of improvement, according to Dzhampapa, occur in a month and a half. The skin is smoothed, wrinkles go away.

This has a positive effect on the skin, microcapillary systems, which provides a better flow to the face of the blood. In addition, there is a restoration of the harm that over the years has been skinned by the sun, harmful nutrition and smoking. Because of all this, our skin is able to stop aging, even more - to look younger. Suppose the skin becomes old at a speed of 97 kilometers per hour, and now - every month - its aging will slow to 80, 65, 48, 31 kilometers per hour and at this level it will remain.

Also, dietary supplements and growth factor release agents are used by Jampapa for those who use cosmetic surgery for at least a couple of weeks. This greatly increases the ability of the skin to self-healing, according to the doctor.

In addition to cosmetic effects, there are also psychological effects. For example, Dzhintropin raises the level of energy in the body, resulting in better health. You just do not feel the load of the past years. For those who have received growth hormone stimulation, it is unthinkable to imagine that they may look miserable and clogged as before, like all aging people, they are simply filled with enthusiasm and energy. And given that Gintropin and sex hormones can stimulate, you literally feel the past sexuality, which, it seemed to you, you lost for a long time and irretrievably.


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Role of ultrasound examination of the heart in sport

31 Mar 2017

Athletes of power sports, where isometric load predominates in many respects (that is, muscle contraction lasts a long time, causing the heart to force blood into the loaded muscle), there are strong physical overloads, increasing the likelihood of pathological changes in some organs and tissues (cardiovascular System, for example).

An important aspect is the reception of steroids and growth hormone (their joint intake significantly increases the growth of the walls of the left ventricle), they accelerate the recovery and growth of sports results, while leading to concentric hypertrophy of the myocardium, changes in the lipid profile of the blood, bile stasis, pathological changes in the liver (in In case of abuse of tableted AS), etc., the heart most often undergoes dangerous changes. Risk factors in this case are:

  • Overloads in the prevalence of isometric work lead to the adaptation of the heart, which is manifested in the thickening of the walls of the left ventricle, a similar change can be physiological (that is, play a role in a stronger discharge of blood into the aorta without disruption in work), but also pathological Lead to violations in the work)

  • The joint use of AS and growth hormone during the preparation, also can enhance the development of concentric hypertrophy of the myocardium. This fact is evidenced by the work published in the international journal of sports medicine in 2003
One of the most common ways of studying the heart is ultrasound, the essence of the method is the reflection of the emitted waves by the tissues of the myocardium, the reversed waves return to the source of the signal and on their basis a two-dimensional image is created, which the doctor observes on the screen.

The variation on the ultrasound of the heart is stress-ultrasound, that is, ultrasound examination before and after exercise, it gives more complete information about possible functional and structural changes: ventricular size, ejection fraction, violation of heart rate after exercise. Carrying out echocardiography of the heart muscle, the athlete will be able to monitor possible changes and respond to them in a timely manner. You can buy Mildronate.

It is worth mentioning one more method of ultrasound diagnostics, it is based on the property of an ultrasonic wave to change the frequency due to reflection from moving objects (the frequency varies according to the speed of movement of the object) - dopplerography. The described method makes it possible to study the movement of fluid (including blood) in vessels, atria and ventricles. The study of the movement of blood can show its non-specific current through the heart (for example, the return of blood in the opposite direction when moving through the heart, the so-called regurgitation, can indicate a number of changes in the valves or heart defects).

At the same time, Doppler ultrasonography has proven itself in the study of blood vessels (diagnosis of aneurysms, for example), consider the main risk factors that indicate the relevance of this procedure in athletes:

1. The development of vascular atherosclerosis in the absence of the possibility or desire to conduct biochemical blood tests (lipid profile), the reception of the AS is able to greatly increase the risk of atherosclerotic plaques (especially in the case of strong suppression of estradiol with excessive consumption of aromatase inhibitors)

2. High blood pressure is also a risk factor, and most of the athletes who take AC have repeatedly faced this.

3. The athlete's floor. Men are more likely to suffer from cardiovascular diseases and vascular aneurysms in particular.

Of course, ultrasound studies are not the only means of diagnosis, nevertheless they seem to the author quite a convenient, universal method for diagnosing the state of the heart, as well as other organs and tissues. Particularly important is the method presented for athletes with the above risk factors.


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Painkiller for Menstrual pain

30 Mar 2017

Menstruation - a unique natural mechanism for regeneration of the mucous membrane of the uterus, which can hardly be called a "gift of nature." The onset of menstruation is completing another cycle ovulatory activity and is an indication of lack of conception in the previous time interval. Many women experience during menstruation discomfort in the abdomen. Worry about it not worth it, because in most cases it is quite normal. After all, during menstruation separates the inner layer of the uterus (endometrium), which rejected every month, if the woman is not pregnant. Uterus, disposing of the endometrium is reduced, evolved prostaglandins irritate pain receptors, all this causes discomfort in the abdomen.

Painkiller for Menstrual pain

Legal aspect

The legislation of the Russian Federation does not provide registration sheet of temporary disability during menstruation. Skim the list of states in which the hospital is issued, we do not find there even a hint of the month.

Menstruation itself is certainly not a diagnosis, but a physiological process for the female body. But as menstrual pain, about which we are speaking, it is all different. If the pain interferes with full wage employment, it may already be a wake-up call. Experts call pain during "dysmenorrhea" monthly term. Dysmenorrhea can be observed in healthy women at the same time can be a symptom of some gynecological diseases.

Algomenorrhea (dysmenorrhea) - pain that accompanies rejection of the endometrium due to violation of neuro, behavioral and metabolic functions and in some cases accompanied by temporary disability and negative changes in the psychosomatic status. Dysmenorrhea can be caused by various causes: hormonal imbalance, impaired structure or function of the ovaries or the uterus, endometriosis, psychoemotional overexertion. An accurate diagnosis by a medical doctor.

For algodismenorrhea often characterized by the presence not only of pain in the abdomen, but also Dumb other unpleasant symptoms:

general weakness, dizziness, fainting;

dry mouth, flatulence, nausea, vomiting, loss of appetite;

temperature increase;

increase or decrease in blood pressure;

pastoznost and swelling of the feet;

situational emotional and mental lability, sleep disorder.

Severe pain during menstruation occur in the following diseases:

endometriosis

adenomyosis

Ovarian cyst

hysteromyoma

uterine Polyps

Few facts about menstruation

According to a study conducted by the international medical resource Counsel & Heal, every fifth of the fair sex is experiencing severe pain during menstruation.

As a rule, a relief state is reached the uncontrolled intake of pills abstract abdominal pain, are not always shown with menstrual pain.

The global trend of respect for women's periodic pain vividly confirmed by the introduction of labor contracts the possibility of "short-expected fall ill" in Japan, Indonesia, Taiwan and Canada. The number of countries that recognize the right of women to rest during menstruation, is growing steadily.

It is necessary to go back to the pain, or rather, no longer come back to it!

Understanding the nature of menstrual pain, you can begin to take action for its relief.

Therapy algodismenorei treat many different disease states that can not be aimed at eliminating the source of pain. The main task is the available treatment of gynecological diseases (if any), the exclusion of precipitating factors and, of course, pain relief, it is desirable to choose a drug that meets the following criteria:

high speed operation;

ease of regimen and dosing;

The preferred method of «per os» injection;

minimum number of side effects.

With this task can handle modern combined preparation - NEXT.

NEXT - it is scientifically sound and accurate balance of the central action analgesic and NSAID.

Targeted action NEXT concentrated in each tablet and helps:

neutralize menstrual pain in the abdomen;

eliminate radiates pain during menstruation, extending to the lumbar spine, in the legs and pelvic organs;

to normalize body temperature, helping to improve the overall condition of the woman.

Dieting can also relieve pain during menstruation. It is usually recommended to exclude alcoholic beverages and smoking, limit the amount of fried, salty and spicy food, flour products.

P.S

Women's nature is specific and unique, with the happiness of having children, many women are forced to bear the burden of pain. Due to the rapid progress of science and technology, pharmaceuticals able to protect the weaker sex from the debilitating manifestations algodismenorei.

Let NEXT to help! Do not leave any chance to abdominal pain in these difficult days!


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How Afobazol (Fabomotizole) acts

30 Mar 2017

Afobazole (fabomotizole) restores nerve cells and protects against the devastating effects of stress.

afobazole, afobazol stress

Resources nerve cells are depleted, and the structure of the membrane receptors is disrupted, resulting receptors fail to respond to inhibitory signals.

This leads to an increase in symptoms: anxiety, stress, irritability, anxiety and other - even with a decrease in the action of stress factor.

"Restores nerve cells" means the restoration of damaged structures and functions of cells damaged by the action of Afobazol (fabomotizole).

The original innovative formula of Afobazol (Fabomotizole)

fabomotizole, afobazol, afobazole

The unique formula Afobazol: fabomotizole repairs ("repairs") receptors of nerve cells and protects cells from damage, including under stress, restoring their performance.

Due to this the nervous system can operate normally even in conditions of prolonged stress.

Action afobazole confirmed by research

  • -78% of patients reported - reducing irritability and bad temper
  • -70% of patients have noted - reduced fatigue and increase efficiency
  • -2-fold reduced anxiety levels


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Drug Peptide Selank against Generalized Anxiety Disorder

30 Mar 2017

Generalized anxiety disorder

Selank promotes the prompt elimination of the imbalance of regulatory systems in the brain that causes the formation of feelings of anxiety, anxiety and fear. In particular, thanks Selank:

Selank reduced levels of anxiety, fear, inner tension;
Selank decreases the level of depression;
Selank optimized operations emotional centers of the brain;
Selank improved behavior;
Selank improves memory thanks to the influence on all stages of the formation of the memory trace (storage, processing / structuring, reproduction of the information;
Selank improves concentration;
Selank increased tolerance to stressful situations, especially when changing the environment community;
Selank stimulated performance, including thin;
Selank improved sleep;
Selank normalizes the autonomic centers.

Selank is the drug of choice for socially active patients who want to preserve their way of life and full operability while minimizing the negative effects experienced by stress and related anxiety and psycho-vegetative disorders.

Treatment of anxiety disorders drug "Selank"

Generalized anxiety disorder Selank

Anxiety disorders are frequent border psychoneurological pathology. Anxiety disorders are often particularly susceptible persons of working age, which leads to disruption of adaptation in daily life, significant economic losses.

Two of the most common anxiety disorders are adaptive disorder with anxious mood, and generalized anxiety disorder.

With adaptive disorder of excessive anxiety or other emotional reactions developed in conjunction with the difficulties of adaptation to a particular stressful situation: patients have the sleep disturbances, appetite changes, non-specific complaints on the part of the cardiovascular system and gastrointestinal tract, difficulty concentrating, irritability, increased exhaustion and fatigue.

Generalized anxiety disorder is characterized by frequent or constant fear and anxiety that arise about the real events or circumstances that cause human concerns, but clearly excessive in relation to them (unjustified, exaggerated fears).

Anxiety in generalized anxiety disorders is global and is formed regardless of the particular event. Excessive anxiety is saved permanently and is directed onto the set of life circumstances. Anxiety, tension and fear and may be accompanied by physical ailments, such as "nervous stomach", shortness of breath and heart palpitations. For many people, along with anxiety disorders, depressive disorders are.

In addition to the persistent anxiety of the main symptom, which unites all the anxiety disorders, their symptoms are following:

fearfulness, impatience, restlessness, feeling of constant tension, inability to relax, impaired concentration, decreased mental capacity and memory, sleep disorder.

When anxiety disorders revealed a high prevalence of cardiovascular, gastrointestinal, allergic diseases, diseases of the musculoskeletal system, metabolic and kidney diseases, respiratory disorders, and migraines.
The presence of high anxiety increases the likelihood of fatal myocardial infarction by 1.9 times, the sudden death of 4.5 times.

Selank Dosage at treatment against Generalized anxiety disorder

Rules of admission "Selank"

The daily dosage of Selank - Reception 14-21 days;

Duration of reception - 3 drops in each nostril 2 times a day;

The amount of the drug on the course - The course of 4 bottles; 3-4 courses per year.

Note:

- In the vial contains 60 drops

- Instill produce strictly to the nasal mucosa, preventing the flow of the nasopharynx.


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Drug Peptide Selank against Neurasthenia

30 Mar 2017

Neurasthenia

Selank promotes the prompt elimination of the imbalance of regulatory systems in the brain that causes the formation of feelings of anxiety, anxiety, fear and irritable weakness:

Selank reduces the level of anxiety, fear, inner tension;

Selank decreases the level of depression;

Selank optimized operations emotional centers of the brain;

Selank stimulated performance, including thin;

Selank improves concentration;

Selank increased tolerance to stressful situations, especially when changing the environment community;

Selank improved sleep;

Selank stimulates memory because of the influence on all stages of the formation of the memory trace (storage, processing / structuring, reproduction of the information;

Selank normalizes the autonomic centers.

The scheme of treatment of neurasthenia drug "Selank 0.15%"

Neurasthenia selank peptide

All this taken together defines the plasticity of the pharmacological and therapeutic effects Selank.

In patients with high levels of anxiety disorders Selank is pronounced anxiolytic effect.

In patients with increased mental exhaustion and physical weakness is more pronounced stimulating anti-asthenic effect of the drug. Thus, Selank is the first representative of a class of "smart" drugs.

Neurasthenia (asthenic neurosis), a disease in which there is increased, uncontrolled irritability, fatigue, anxiety, frequent changes of mood, there are complaints of general weakness, dizziness, tremors in the limbs, bad dream.

Currently, the group of neurotic disorders include conditions in which the development of a leading role for the production of stress caused by a triad of factors: the absorption of a large amount to be meaningful information, lack of time and the high motivation of activity ( "Information neurosis", "manager" syndrome).
They arise from the persons holding administrative positions and working in a situation of increased responsibility, competition, uncertainty in the outcome of their endeavors. It emphasizes the pathogenic role of mental and physical exhaustion, chronic lack of sleep, emotional overload.

The appearance of symptoms of neurasthenia also contributes asthenic constitution, malnutrition, vitamin deficiency, severe somatic diseases and intoxications.

The main symptom of neurasthenia - asthenia: increased mental and physical fatigue, confusion, weakness, decreased performance, the need for a long vacation, not giving, however, a complete recuperation.

Increased mental exhaustion combined with excessive excitability (the phenomenon of irritable weakness).

For frequent neurotic symptoms are also tension headaches, sleep disorders, multiple somatic vegetative disorders (sweating, abnormalities in the cardiovascular, gastrointestinal, respiratory, sexual function, and others.).

Selank Dosage at treatment against Neurasthenia

Rules of admission "Selank"

The daily dosage of Selank - Reception 14-21 days;

Duration of reception - 3 drops in each nostril 2 times a day;

The amount of the drug on the course - The course of 4 bottles; 3-4 courses per year.

Note:

- In the vial contains 60 drops

- Instill produce strictly to the nasal mucosa, preventing the flow of the nasopharynx.


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Afobazol (Fabomotizole) Benefits and Advantages

30 Mar 2017

Action research is confirmed

Afobazole (Fabomotizole): BROAD BASE OF RESEARCH - More than 80 articles describing the study the efficacy and safety Afobazol in clinical practice, involving more than 4500 patients.
Afobazol (Fabomotizole): investigated in various fields of medicine:
Cardiology
Dermatology
Neurology
pulmonology
gastroenterology
Gynecology
Psychiatry.

Afobazole Restores nerve cells

The unique formula Afobazol (INN fabomotizole) regenerates ("repairing") receptors of nerve cells and protects cells from damage, including under stress, so that they can once again do their job correctly.

The result: disappearing anxiety, tension, irritability, restlessness, there are strength and confidence, informed decisions and actions, improving the emotional background.

Afobazole operates without drowsiness
Unique Afobazol formula (INN fabomotizole) running through the natural physiological mechanisms of repair of nerve cells without affecting the sharpness and response speed of the nervous system, without effect "sleepy".

Afobazole not causes:
daytime sleepiness
reducing memory and concentration
miorelaxation
addiction
depending on
withdrawal.

Afobazol can be taken by:

drivers
people working on the complex mechanisms
wherever saving concentration required.

Thus, afobazole fits all working and living in the modern world people.

The innovative formula of Afobazole (INN fabomotizole)

Afobazol is one of the most popular and has a favorable safety profile, anti-anxiety medications in Russia. It was created in the name of the Research Institute of Pharmacology RAMS V. Zakusov headed by Academician of RAMS SB Seredenin and, unlike many traditional drugs for the treatment of anxiety, has no inhibitory effect on the central nervous system. In addition, the originality of the drug lies in the ability to restore the natural mechanism that allows the nervous system to cope with stressful workloads.

Afobazol acts quickly
Effect Afobazol seen from the first week of admission: a decline of anxiety, tension, irritability, restlessness;
The maximum effect Afobazole developed by the end of the 4th week of treatment;
The effect of receiving Afobazole persists after completion of therapy.

Afobazol Recognized by WHO experts

fabomotizole, afobazol, afobazole buy

In 2014, the World Health Organization decided to include fabomotizole drug (Afobazol) in the class of anxiolytics (anti-anxiety medications), an international classification system for medicines - Anatomical Therapeutic Chemical Classification System, ATC.

Afobazol was created in the Research Institute of Pharmacology. VV Zakusov Medical Sciences under the leadership of academician of RAMS SB Seredenin as a result of many years of research selective anxiolytic, has effective traditional benzodiazepine tranquilizers and deprived of their inherent side effects. Afobazol efficacy and safety have been studied in numerous experimental and clinical studies.

Data on the development of the drug have been submitted for consideration by the WHO, with the result that in 2012 it was decided to award afobazole international nonproprietary name - fabomotizole. In 2013, the information obtained in the study Afobazol mechanism of action in the Russian and foreign laboratories, as well as the results of studies of its efficacy and safety have been submitted for consideration by the WHO Centre for Methodology of statistical research of drugs (The WHO Collaborating Centre for Drug Statistics Methodology), which It is the coordinating body and contributes to the wide international spread of ATS methodology. The results of the study of the mechanism of action and anxiolytic fabomotizole evidence base were discussed at the meeting of the WHO International Working Group. Submission of documentation consistent with the requirements of the WHO, which served as the basis for the assignment to the international ATC code as an anxiolytic (antianxiety) preparation (N05B - ANXIOLYTICS).
It was received during the period review submitted documentation and the proposed ATC code comments and objections. Voted ATC code was included in the ATC classification since January 2015. Afobazol OTC became the first Russian anxiolytic, received by the World Health Organization code of the international classification.


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