Instructions / Instruction for use: Sinemet SRI want this, give me price
Dosage form: Controlled release tablets
Active substance: Levodopa + Carbidopa*
N04BA02 Levodopa and a decarboxylase inhibitor
Dopaminomimetics in combination
Antiparkinsonics in combination
The nosological classification (ICD-10)
G20 Parkinson's disease: A trembling paralysis; Idiopathic Parkinsonism; Parkinson's disease; Symptomatic Parkinsonism
G21 Secondary Parkinsonism: Medicinal Parkinsonism; Parkinsonism; Parkinsonism symptomatic; Disorders of extrapyramidal system; Parkinson's Syndrome
Composition and release form
1 tablet Sinemet contains carbidopa 25 mg and levodopa 250 mg; In a blister 10 pcs., In a box of 10 blisters.
1 tablet Sinemet SR - carbidopa 50 mg and levodopa 200 mg; In a blister 10 pcs., In a box of 10 blisters.
Mode of action - antiparkinsonian, dopaminergic.
Indications of the drug Sinemet SR
Disease and Parkinson's syndrome: rigidity, bradykinesia, tremor, dysphagia, sialoreya, postural body sway.
Hypersensitivity undiagnosed skin disease, a history of melanoma, angle-closure glaucoma, pregnancy, lactation, age (18 years).
Dyskinesia (blepharospasm, muscle twitching, choreiform, dystonic, and others. Involuntary movements), transient psychosis, depression, dementia, dizziness, drowsiness, lack of appetite, nausea, vomiting, bleeding from the gastrointestinal tract, development of duodenal ulcer, palpitations, orthostatic hypotension, pain Behind the sternum, shortness of breath, anemia, thrombocytopenia, agranulocytosis, paresthesia.
Incompatible with MAO inhibitors. Combination with antihypertensive drugs can potentiate orthostatic hypotension. Phenothiazines, butyrophenones can reduce the therapeutic effect, phenytoin and papaverine - level it. With a high-protein diet, absorption of levodopa may be impaired.
Dosing and Administration
Inside. Individual dose selection is recommended. The initial dose is 1/2 table. 1-2 times a day; If necessary add to 1/2 table. Every day or every other day (until the optimal effect is obtained); The maximum daily dose is 8 tablets.
Carefully prescribed to patients with serious diseases of the cardiovascular system, lungs (including asthma), kidney, liver and endocrine system, peptic ulcer history, convulsions, chronic open-angle glaucoma. It is recommended to periodically monitor the functions of the liver, hematopoietic and cardiovascular systems, kidneys. Cancel should be gradual.
Storage conditions of the drug Sinemet SR
In a dry, the dark place at a temperature of 2-30 ° C.
Keep out of the reach of children.
Shelf life of the drug Sinemet SR
Do not use after the expiry date printed on the package.