Instructions / Instruction for use: ArtrotecI want this, give me price
Active substance Diclofenac + Misoprostol
ATX Code M01AB55 Diclofenac in combination with other drugs
NSAIDs - Acetic acid derivatives and related compounds
Nosological classification (ICD-10)
M06.9 Other specified rheumatoid arthritis
Rheumatoid arthritis,Pain syndrome in rheumatic diseases, Pain in rheumatoid arthritis, Inflammation in rheumatoid arthritis, Degenerative forms of rheumatoid arthritis, Children's rheumatoid arthritis, Exacerbation of rheumatoid arthritis, Acute articular rheumatism, Rheumatic arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatoid arthritis of active course, Rheumatoid arthritis, Rheumatoid polyarthritis, Acute rheumatoid arthritis, Acute rheumatism
M45 Ankylosing spondylitis
Ankylosing spondylarthrosis, Marie-Strumpel disease, Ankylosing spondylitis, Pain syndrome in acute inflammatory diseases of the musculoskeletal system, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Bechterew's disease, Ankylosing spondylitis, Diseases of the spinal column, Rheumatic spondylitis, Bechterew-Marie-Strumpel disease
R52.2 Other constant pain
Pain syndrome, rheumatic origin, Pain at vertebral lesions, Pain in the chamber, Pain for burns, Pain syndrome weak or moderate, Perioperative pain,Moderate to severe pain, Moderately or weakly expressed pain syndrome, Moderate to severe pain, Ear pain of otitis, Neuropathic pain, neuropathic pain
Composition and form of release
1 coated tablet contains diclofenac sodium 50 mg or 75 mg and misoprostol 200 μg; in the blister 10 pcs., in the box 2 blisters.
Pharmacological action - anti-inflammatory, antipyretic, analgesic.
Diclofenac inhibits cyclooxygenase and reduces the formation of PG (prostaglandins). Misoprostol (synthetic analogue PGE1) prevents the negative effect of diclofenac on the mucosa and the development of NSAIDs (nonsteroidal anti-inflammatory drugs) -gastropathy.
Misoprostol is rapidly absorbed and metabolized to the active metabolite - misoprostol acid, the latter has a decay period of about 30 min. 70% of the administered dose of misoprostol is excreted in the urine as inactive metabolites. Diclofenac sodium is also rapidly and almost completely absorbed, reversibly binds to plasma proteins; from 40 to 60% is excreted in the urine, the rest - with bile and feces.
Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, pain syndrome of various etiologies, rheumatic diseases.
Hypersensitivity, bleeding (including gastrointestinal).
pregnancy and lactation
Digestive disorders (gastrointestinal tract) (abdominal pain, nausea, dyspepsia, flatulence, diarrhea); decreased platelet aggregation, prolonged bleeding time, fluid retention and edema (especially in predisposed patients), menorrhagia and metrorrhagia in pre- and post-menopausal women, headache, dizziness, skin rash.
Dosing and Administration
Inside, not liquid, during meals, 1 table. 2-3 times a day.
Caution is prescribed for patients with congestive heart failure, impaired renal function, predisposition to fluid retention in the body.
In a dry place, at a temperature of no higher than 25 ° C.
Keep out of the reach of children.
Do not use after the expiry date printed on the package.