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Instruction for use: Afonilum SR

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Dosage form: Capsules of prolonged action; Capsules retard; Capsules retard forte

Active substance: Theophylline


R03DA04 Theophylline

Pharmacological group

Adenosinergic agents

The nosological classification (ICD-10)

J43 Emphysema: Interstitial emphysema; Emphysema of the lungs; Chronic lung diseases; Chronic Obstructive Pulmonary Diseases; Obstructive emphysema of the lungs; Chronic emphysema of the lungs; Chronic obstructive pulmonary emphysema

J45 Asthma: Asthma of physical effort; Asthmatic conditions; Bronchial asthma; Bronchial asthma of light course; Bronchial asthma with difficulty in sputum discharge; Bronchial asthma of severe course; Bronchial asthma physical effort; Hypersecretory asthma; The hormone-dependent form of bronchial asthma; Curbing asthma attacks with bronchial asthma; Non-allergic bronchial asthma; Night Asthma; Exacerbation of bronchial asthma; Attack of bronchial asthma; Endogenous forms of asthma; Night attacks of asthma; Cough with bronchial asthma

Composition and release form

1 capsule retard contains theophylline 250 mg; In the package 20 pcs.

1 capsule retard forte - 375 mg; In the package 20 pcs.

1 capsule with sustained release contains theophylline 125 mg or 500 mg; In the package of 20, 50 or 100 pcs.


Mode of action - diuretic, vasodilating, cardiotonic, bronchodilator, anti-asthmatic.

Inhibits phosphodiesterase.

Indications of Afonilum SR

Bronchial asthma, asthmatic bronchitis, obstructive pulmonary emphysema (with reversible bronchospasm).


Hypersensitivity, acute myocardial infarction, tachyarrhythmia, peptic ulcer and duodenal ulcer, hypertrophic obstructive cardiomyopathy, unstable angina, hyperthyroidism, porphyria.

Application of pregnancy and breastfeeding

With caution before childbirth - reduces the contractile activity of the myometrium.

Side effects

Dyspeptic disorders (heartburn, nausea, vomiting, diarrhea), headache, agitation, anxiety, insomnia, tremor, irritability, tachycardia, arrhythmias, hypotension, heart failure, hypercalcemia, hypercreatinemia, hyperkalemia, increased diuresis.


Strengthens the effect of sympathomimetics, reduces - beta-blockers and lithium preparations. Rapidly metabolized against the background of stimulants of microsomal oxidation of hepatocytes (barbiturates); The administration of inhibitors of microsomal oxidation leads to a delay in excretion.

Dosage and Administration

Inside, not liquid, after eating, squeezed a sufficient amount of fluid, adults and children from 8 years - 2-3 caps. in a day. If the patient is not able to swallow the capsule, it can be opened and, without chewing, take the contents.

Storage conditions of Afonilum SR

At room temperature.

Keep out of the reach of children.

Shelf life of the drug Afonilum SR

Capsules retard forte 375 mg - 5 years.

Capsules retard 250 mg - 5 years.

Capsules of prolonged action 125 mg - 5 years.

Capsules prolonged action 500 mg - 3 years.

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