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Polyoxidonium (Polioksidoniy, Azoximeri bromidum, Azoximer bromide) - tablets 12 mg has immunomodulatory effects. The preparation increases the resistance of the body against bacterial, fungal and viral infections. The basis of the mechanism of immunomodulatory effects Polyoxidonium is to increase the ability of white blood cells phagocytose microbes and stimulate initially at low rates the production of cytokines that activate the immune system, increases antibody to infectious agents.
Polyoxidonium activates phagocytes of peripheral blood and tissue macrophages, which contributes to more rapid elimination of the pathogen from the body in the presence of the infection. Furthermore, Polyoxidonium activate lymphoid cells in the regional lymph nodes, namely the B-cells that produce secretory IgA.
With sublingual application Polyoxidonium activates lymphoid cells in the nasal cavity, the Eustachian tubes, oropharynx, bronchi. Furthermore, Polyoxidonium saliva activates bactericidal properties.
When administered orally Polyoxidonium also activate lymphoid cells located in the intestinal lymph nodes.
The consequence of this is to increase the stability of the respiratory, gastrointestinal and upper respiratory tract to infectious agents.
Along with immunomodulatory effects, has expressed Polyoxidonium detoxification and antioxidant activity, has the ability to rid the body of toxins, heavy metals, inhibits lipid peroxidation. These properties are determined by the structure and nature of the high-molecular Polyoxidonium
Application Polyoxidonium on the background of secondary immunodeficient states to improve the efficiency and reduce the duration of treatment, significantly reduce the use of antibiotics, bronchodilators, corticosteroids, lengthen remission.
The drug is well tolerated, does not have mitogenic, polyclonal activity, antigenic properties, it does not have allergenic, mutagenic, embryotoxic, teratogenic and carcinogenic effects.
Polyoxidonium is used in adults and adolescents over 12 years for the treatment and prevention of infectious and inflammatory diseases (viral, bacterial and fungal etiologies) are not amenable to standard therapy. Polyoxidonium used both in the acute stage, and in remission:
in the treatment of:
Polyoxidonium pills 12 mg administered orally and sublingually for 20-30 minutes before eating daily 1, 2 or 3 times a day: adults - in doses of 12 mg or 24 mg, teenagers from 12 years - at a dose of 12 mg. The method and dosing schedule determined by the physician depending on the diagnosis, severity and the severity of the process.
Recommended regimen for
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