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Hemostatic system

23 Oct 2016

Biophysicist Dr. Doping tells about mortality from hemorrhage, the role of platelets in the body and the blood coagulation system. How does the system of hemostasis? What are the main features of this system? What is the role played by platelets in the body? How are the main methods of treatment of disorders of the hemostatic system?

If we talk about the different systems of the human body, the hemostasis system, which is responsible to stop bleeding in wounds, hemorrhages and other types of violations of the integrity of the vascular system, is the most problematic in our body. People may have a variety of diseases, but they die more often from disorders of hemostasis.

Our body has several levels of protection against bleeding and haemorrhage. One level - is vascular hemostasis. Muscle contraction in certain situations can lead to a narrowing of blood vessels (vasoconstriction) and slow down or even halt some minor bleeding. The next layer - platelet hemostasis. Special cells are present in our blood - platelets, which stick together in case of damage to the plug and seat damage. Platelet bit them about 10 times smaller than red blood cells, and the size (assuming per volume) are an order of magnitude or two lower. So apparently it seems that platelets are not very many. Nevertheless, they are vital to stop the bleeding. The third level - the blood clotting system - artful cascade of reactions in the blood plasma, which is completed by the fact that a specialized protein fibrin begins to polymerize and make three-dimensional grid. Such a three-dimensional network at the micro level can hold within themselves the amount of water that is a thousand times superior to its weight.

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Given how difficult it is arranged hemostasis system, in a sense, it is not surprising that we have problems with the diagnosis of its disorders and their adequate treatment. What people do during the XX century, to a great extent it was the result of empiric selection of therapy methods or diagnostic methods of the invention.

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