Instruction for use: Venolife

Dosage form: Gel for external use

Active substance: Heparinum natrium + Dexpanthenolum + Troxerutinum

ATX

C05BA53 Heparin in combination with other drugs

Pharmacological group

Anticoagulants in combination

The nosological classification (ICD-10)

I80 Phlebitis and thrombophlebitis: Diseases of peripheral vessels; Inflammation of superficial veins; Inflammatory diseases of veins; Deep venous thrombophlebitis; The disease of veins; Disease of the veins of the lower extremities; Diseases of peripheral vessels; Migrating phlebitis; Insufficiency of veins of lower extremities; Exacerbation of chronic thrombophlebitis; Acute thrombophlebitis; Acute thrombophlebitis of superficial veins; Periphlebitis; Periflebit surface; Superficial inflammation of veins; Surface thrombophlebitis; Surface phlebitis; Thrombophlebitis; Deep vein thrombophlebitis; Thrombophlebitis superficial; Phlebitis; Phlebitis of deep veins; Phlebitis of superficial veins; Phlebopathy; Chronic thrombophlebitis; Endophlebitis

I83 Varicose veins of lower extremities: The feeling of heaviness and fatigue in the lower limbs; Varicose disseminated type; varicose veins; Varicose veins of the lower extremities; Varicose disease of lower limbs; Varicose superficial veins; Varicose veins; Varicose vein disease; varicose syndrome; varicose syndrome; Venous claudication; venous varices; venous disease; The disease of the lower extremities; Prevarikozny syndrome; Predvarikozny syndrome; Chronic varicose veins; Sclerotherapy varices

I87.0 Postphlebitic syndrome: post-thrombotic venous insufficiency; Postthrombotic disease; Post thrombophlebitic syndrome; Post-thrombophlebitis; Post-thrombophlebitic syndrome; Postphlebitic syndrome; Post thrombotic syndrome; Postphlebitic syndrome (stasis syndrome)

I89.8 Other specified non-communicable diseases of lymphatic vessels and lymph nodes

L98.4.2 * Trophic skin ulcer: Varicose ulcer; Varicose ulcers; Cutaneous ulcer; Non-healing ulcers; Trophic ulcer; Trophic ulcer of lower leg; Trophic skin lesions; Trophic after-burn ulcers; Trophic ulcers; Trophic skin ulcers; Ulcer of lower leg; Ulcer of skin; Ulcer of trophic skin; Ulcer on legs; Ulcerative necrosis of the skin; Ulcer of shin; Ulcer of the lower leg; Ulcers of lower extremities; Difficult healing ulcers

T14.0 Superficial injury of unspecified area of the body: Abrasions; Scratch; Skin Wounds; Wounds of soft tissues; Hematoma; Hematoma of traumatic origin; Hematomas; Hematomas of muscles; Hematomas of soft tissues; Healing of the skin; Bruise; Bruising due to sprains and bruises; Microtrauma; External bruises; Small combing; Superficial hematoma; Superficial damage to the skin and mucous membranes; Subcutaneous hematoma; Post-traumatic hematoma; Post-traumatic disturbance of microcirculation; Skinness of the skin; Traumatic plexus lesions; Injury; Contusion of soft tissues; Joint bruise; Traumatic bruises; Traumatic injury; Primary treatment of surface contaminated wounds; Abrasion; Bruise

T14.3 Dislocation, sprain and damage to the capsular-ligamentous apparatus of the joint of the unspecified area of the body: Painful stretching of the muscles; Pain and inflammation in tension; Dislocation of dislocation; Degenerative changes in the ligamentous apparatus; Edema due to sprains and bruises; Edema after interventions during sprains; Damage and rupture of ligaments; The musculoskeletal system is damaged; Damage to ligaments; Damage to the joints; Ligament ruptures; Tendon tendons; Ruptures of the tendons of muscles; Stretching; Crick; Stretching of the muscle; Sprain; Tension of the tendons; Extensions; Stretch muscles; Sprains; Tension of the tendons; Injury of the musculoskeletal system; Injuries to the joints; Injuries of capsule-articular tissues; Injuries of the osteoarticular system; Injuries to ligaments; Injuries to the joints; Joint wounds; Stretching of the ligamentous apparatus; Stretching of the ligamentous apparatus; Habitual stretching and tearing

Composition and release form

Gel for external use - 100 g

Troxerutin 2 g; Dexpanthenol 5 g

Heparin sodium 0.25 g (30000 units)

Auxiliary substances: phenylethyl alcohol, propylene glycol, carbomer 940 or 980, trometamol, purified water

In an aluminum tube 30 or 40 g; In a pack of cardboard 1 tuba

Pharmachologic effect

Mode of action - Anti-inflammatory, angioprotective, venotonic, anticoagulant.

Venolife® gel is a combined preparation for external use, the pharmacological properties of which are determined by the action of the substances in its composition.

Heparin - an anticoagulant of direct action, a natural anticoagulant factor of the body - has an anti-inflammatory effect, promotes the regeneration of connective tissue due to inhibition of hyaluronidase activity; Prevents thrombogenesis, activates the fibrinolytic properties of the blood; Improves local blood flow.

Dexpanthenol - provitamin B5 - in the skin turns into pantothenic acid, which is a part of coenzyme A, which plays an important role in the processes of acetylation and oxidation; Improving metabolic processes, dexpanthenol promotes the regeneration of damaged tissues; Improves the absorption of heparin.

Troxerutin is an angioprotective agent; Has P-vitamin activity, in particular, it reduces vascular-tissue permeability and fragility of capillaries, promotes normalization of microcirculation and trophism of tissues, reduces stagnant phenomena in veins and parainous tissues, has anti-edematous and anti-inflammatory effect.

In addition, due to the presence of a preservative-antiseptic of phenylethyl alcohol, the drug has a bactericidal and fungicidal effect, helping to prevent infection of the wound surface. The composition of the gel base provides the preparation with moderate hyperosmolar properties.

Indications for Venolife

Osteo-pain syndrome and microcirculatory-trophic disorders caused by venous insufficiency of the lower extremities (varicose veins, acute and chronic thrombophlebitis, postthrombophlebitic syndrome, chronic lymphostasis);

- trauma of soft tissues (hematomas, dislocations, sprains);

- to accelerate the granulation and epithelization of trophic ulcers in the regeneration phase (in the absence of pronounced exudation).

Contraindications

Hypersensitivity to the components of the drug, open infected wounds or wounds with heavy exudation.

Pregnancy and breast-feeding

Venolife® is not contraindicated in pregnancy and lactation.

Side effects

There are local manifestations of allergic reactions (skin rash, itching).

Interaction

Interactions of the drug with other drugs have not been identified.

Dosing and Administration

Topical. Apply a thin layer on the affected area and around it 2-3 times a day, evenly spreading on the surface of the skin with light rubbing movements until completely absorbed. The course of treatment is 2-3 weeks. The need for further treatment is determined by the attending physician, based on the severity of the pathological process and the results of clinical analyzes. If the disease recurs, the course of treatment can be carried out 2-3 times a year.

With trophic ulcers with mild exudation before the application of the preparation, the wound surface is cleaned of exudate and necrotic tissues, if necessary, washed with a solution of hydrogen peroxide 3%, furacilin 1: 5000 or chlorhexidine bigluconate 0.05% and dried. The gel is applied in a uniform thin layer so that the entire affected area is covered with the preparation and a sterile gauze bandage is applied. Change dressings are carried out once a day. With the open method of treatment, the drug is applied 1-2 times a day. The duration of treatment is determined by the dynamics of epithelialization.

Special instructions

Venolife® is not intended for use in ophthalmology, for intravaginal and rectal administration.

Storage conditions of the drug Venolife

At a temperature of 15-25 ° C.

Keep out of the reach of children.

The shelf life of the drug Venolife

2 years.

Do not use beyond the expiration date printed on the package.