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Instruction for use: Trihistaglobulinum siccum

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Dosage form: Powder lyophilized dosed

Pharmacological group:


The nosological classification (ICD-10)

H10.1 Acute atopic conjunctivitis: Allergic conjunctivitis; Allergic eye diseases; Allergic conjunctivitis; Allergic conjunctivitis caused by chemical and physical factors; Allergic rhinoconjunctivitis; Allergic inflammation of the eyes; Spring Qatar; Spring keratitis; Spring conjunctivitis; Conjunctivitis allergic; Year-round allergic conjunctivitis; Exacerbation of pollinosis in the form of rhinoconjunctival syndrome; Acute allergic keratoconjunctivitis; Acute allergic conjunctivitis; Superficial bacterial infection of the eyes; Rhinoconjunctivitis; Seasonal allergic conjunctivitis; Seasonal conjunctivitis; SENSORY; Chronic allergic keratoconjunctivitis; Chronic allergic conjunctivitis

J30 Vasomotor and allergic rhinitis: Allergic rhinopathy; Allergic rhinosinusopathy; Allergic diseases of the upper respiratory tract; Allergic rhinitis; Allergic rhinitis seasonal; Vasomotor runny nose; Prolonged allergic rhinitis; All-year-round allergic rhinitis; All-year allergic rhinitis; Year-round or seasonal allergic rhinitis; All-the-year-round rhinitis of an allergic nature; Rhinitis vasomotor allergic; Exacerbation of pollinosis in the form of rhinoconjunctival syndrome; Acute allergic rhinitis; Edema of the nasal mucosa; Edema of the nasal mucosa; Edema of the mucous membrane of the nasal cavity; Swelling of the nasal mucosa; Swelling of the nasal mucosa; Pollinosis; Permanent allergic rhinitis; Rhinoconjunctivitis; Rhinosinusitis; Rhinosinusopathy; Seasonal allergic rhinitis; Seasonal allergic rhinitis; Hay rhinitis; Chronic allergic rhinitis; Allergic diseases of the respiratory tract

J31 Chronic rhinitis, nasopharyngitis and pharyngitis: Allergic rhinosinusopathy; Inflammation of the nasal mucosa; Infectious and inflammatory diseases of ENT organs; Catarrh of the nasopharyngeal region; Year-round rhinitis; Ozena; Persecution in the throat or nose; Rhinitis hyperplastic; Rhinitis chronic; Pharyngoesophagitis; Chronic Bacterial Rhinitis

J32 Chronic sinusitis: Allergic rhinosinusopathy; Purulent sinusitis; Catarrh of the nasopharyngeal region; Catarrhal inflammation of the paranasal sinuses; Exacerbation of sinusitis; Sinusitis chronic

J45 Asthma: Asthma of physical effort; Asthmatic conditions; Bronchial asthma; Bronchial asthma of light course; Bronchial asthma with difficulty in sputum discharge; Bronchial asthma of severe course; Bronchial asthma physical effort; Hypersecretory asthma; The hormone-dependent form of bronchial asthma; Curbing asthma attacks with bronchial asthma; Non-allergic bronchial asthma; Night Asthma; Exacerbation of bronchial asthma; Attack of bronchial asthma; Endogenous forms of asthma; Night attacks of asthma; Cough with bronchial asthma

J45.0 Asthma with predominance of the allergic component: Asthma of bakers; Allergic lung diseases; Bronchial asthma, professional; Aspirin Asthma; Asthma atopic; Asthma bronchial atopic; Atopic asthma; Atopic bronchial asthma; Persistent atopic bronchial asthma; Allergic diseases of the respiratory tract

L20 Atopic dermatitis: Allergic diseases of the skin; Allergic skin disease noninfectious etiology; Allergic skin disease etiology nemikrobnoy; Allergic skin diseases; Allergic skin lesions; Allergic reactions on the skin; atopic dermatitis; Allergic dermatosis; Allergic diathesis; Allergic itching dermatosis; Allergic skin disease; Allergic skin irritation; allergic Dermatitis; atopic Dermatitis; allergic dermatoses; exudative diathesis; Itchy atopic eczema Itchy allergic dermatosis; Allergic skin disease; Cutaneous allergic reaction to drugs and chemicals; Cutaneous reactions to medications; Skin and allergic disease; Acute eczema; common neurodermatitis; Chronic atopic dermatitis; Exudative diathesis

L30.9 Unspecified Dermatitis: Allergic dermatoses complicated by a secondary bacterial infection; Anal eczema; Bacterial maturation; Varicose Eczema; Venous dermatitis; Inflammation of the skin; Inflammation of the skin upon contact with plants; Inflammatory Skin Disease; Inflammatory Skin Diseases; Inflammatory Skin Diseases; Inflammatory skin reactions; Inflammatory processes of the skin; Hypostatic dermatitis; Fungal Eczema; Fungal dermatosis; Dermatitis; Dermatitis is stagnant; Dermatitis and eczema in the anal area; Dermatitis acute contact; Perianal dermatitis; Dermatosis; Dermatosis of the scalp; Dermatosis of psoriasis; Dermatosis with persistent itching; Dermatoses; Dermatoses itchy; Other itching dermatoses; Significant eczematous manifestations; Itching with dermatoses; Itching eczema; Itching dermatoses; Itching dermatitis; Itching dermatosis; True eczema; Skin reaction to insect bites; Skin itching with dermatosis; Constitutional eczema; Weeping eczema; Drowsing inflammatory skin disease; Dying Infectious-Inflammatory Skin Disease; Non-allergic dermatitis; Nummular eczema; Acute contact eczema; Acute inflammatory skin disease; Acute dermatosis; Acute severe dermatosis; Perianal dermatitis; Superficial dermatosis; Subacute Contact Eczema; Simple dermatitis; Occupational dermatitis; Psychogenic dermatosis; Bubble dermatitis of newborns; Pustular eruptions; Irritation and redness of the skin; Low-flammable eczema; Dry atrophic eczema; Dry eczema; Toxic dermatitis; Ear eczema like dermatitis; Chronic eczema; Chronic dermatosis; Chronic dermatosis; Chronic common dermatosis; Scaly papular dermatosis; Eczema; Eczema anal region; Eczema of the hands; Eczema Contact; Eczema lichenized; Eczema Nummular; Eczema acute; Eczema acute contact; Eczema subacute; Eczematous dermatitis; Eczema-like rashes; Ecome exogenous; Endogenous eczema; Gluteal dermatitis; Limited itching dermatitis

L50 Urticaria: Idiopathic chronic urticarial; Injury Urticaria; Chronic urticarial; Hives of the newborn

T78.3 Angioedema: Edema Quincke; Laryngeal exacerbation with angioneurotic edema; Recurrent angioedema; Allergic edema; Recurrent swelling of Quincy

Composition and release form

1 ampoule with a capacity of 2 ml with 1 dose of lyophilized powder for the preparation of the injection contains the human normal 36 mg immunoglobulin, histamine dihydrochloride 0.00045 mg, sodium thiosulfate 32 mg; In the package of 5 pcs., Complete with 5 ampoules of a solvent of 2 ml (water for injection).

Pharmachologic effect

Mode of action - antiallergic.

Indication of the Trihistaglobulinum siccum

Treatment of severe and resistant forms of allergic diseases during the periods of remission (in adults and children): chronic recurrent urticaria, atopic dermatitis and eczema, atopic bronchial asthma (with the impossibility of using specific therapy with allergens), asthmatic bronchitis, allergic rhinosinusopathy, allergic conjunctivitis, Season of flowering), relapsing edema of Quincke (except for hereditary angioneurotic edema).


Hypersensitivity (including to other blood products), allergic diseases in the acute stage, acute infectious diseases, exacerbation of chronic infections, peptic ulcer of the stomach and duodenum, glomerulonephritis, rheumatism, severe diseases of the nervous, hematopoietic and endocrine systems, diffuse diseases Connective tissue, hypertension II-III degree, malignant neoplasms, specific hypensensitivity, preventive vaccinations, corticosteroid therapy.

Side effects

Dizziness, exacerbation of the underlying disease (with symptoms of malaise, headache, nausea, falling blood pressure, severe weakness, etc.), fever (up to 37.5 C), anaphylactic reactions, incl. shock; Hyperemia of the skin (at the injection site).

Dosing and Administration

SC or IM (previously dissolved). 2 ml (1 dose) for adults - 5-12 injections at intervals of 2 to 5 days (depending on the severity of the disease), children - 4-10 injections, at intervals of 3-7 days; If necessary, the course is repeated 1-2 months in adults and 2 months (at least) in children.

Precautionary measures

With caution apply during menstruation (possibly increased bleeding). In chronic infections and rheumatism appoint after 1 month (no earlier) than after the disappearance of symptoms of exacerbation or during remission.

Storage conditions of the drug Trihistaglobulinum siccum

In dry, the dark place at a temperature of 2-10 C.

Keep out of the reach of children.

Shelf life of the drug Trihistaglobulinum siccum

2 years. The prepared solution is no more than 30 minutes

Do not use after the expiry date printed on the package.

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