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Instructions

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Instruction for use: Serum antigangrenosum polyvalentum purificatum concentratum equinum fluidum

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Dosage form: Suspension for injections

ATX

J06AA05 Antigangrenous Serum

Pharmacological group:

Vaccines, serums, phages and toxoids

The nosological classification (ICD-10)

A48.0 Gas gangrene: wound anaerobic infection; Phlegmon brown; Clostridial myositis; Clostridial Cellulite; Clostridiosis wound; Myonecrosis (gas gangrene)

J85.0 Gangrene and lung necrosis: Gangrene lung; Gangrenous pneumonia

O85 Postpartum sepsis: Postpartum infections; Pelvioperitonitis; Postpartum anaerobic sepsis; Puerperal fever

O86 Other postpartum infections: Postpartum infections; Postpartum infection

R02 Gangrene, not elsewhere classified: Atherosclerotic gangrene; Gangrene; Gangrene of the extremities; The fire of Saint Anthony

Composition and release form

1 ampoule of a multivalent preparation with a preventive dose contains antitoxins against three types of causative agents of gas gangrene. In a set of 1 ampoule of anti-gangrenous serum and 1 ampoule of diluted 1: 100 serum to determine the sensitivity to the horse protein.

Characteristic

Containing specific immunoglobulins, the protein fraction of blood serum of horses, hyperimmunized with anatoxins (toxins) of the three main causative agents of gas anaerobic infection (type A, novemia (dematic), septicum). The serum is purified by peptic digestion and salt fractionation.

Pharmachologic effect

Mode of action - Detoxification.

Neutralizes toxins of anaerobic microbes.

Indication of the drug Serum antigangrenosum polyvalentum purificatum concentratum equinum fluidum

Gas gangrene (treatment and prevention), gangrenous diseases: postpartum anaerobic sepsis, gangrene of the lung, etc.

Contraindications

Not identified.

Side effects

Not identified.

Dosing and Administration

IM, the preventive dose is 30 000 IU; IV (drop), the therapeutic dose - 150 000 IU.

Precaution measures

Before the introduction of serum, it is necessary to prepare anti-shock therapy. The drug is not suitable for use in ampoules with broken integrity or lack of marking, with a change in physical properties (color, transparency, presence of unbreakable flakes), expired shelf life, improper storage.

Storage conditions of the drug Serum antigangrenosum polyvalentum purificatum concentratum equinum fluidum

At a temperature of 2-8 C (do not freeze).

Keep out of the reach of children.

Shelf life of the drug Serum antigangrenosum polyvalentum purificatum concentratum equinum fluidum

2 years.

Do not use after the expiry date printed on the package.

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