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Instruction for use: Serum antidiphtericum equinum purificatum cocentratum liquidum

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Dosage form: Suspension for injections


J06AA01 Diphtheria toxoid

Pharmacological group:

Vaccines, serums, phages and toxoids

The nosological classification (ICD-10)

A36.9 Diphtheria, unspecified

Composition and release form

1 ml of serum contains not less than 1500 IU, preservative - chloroform (in the finished product is not determined); Sodium chloride - up to 0,9%. In ampoules of 10,000 IU (1 dose) or 20,000 IU (2 doses); In the package 5 ampoules of serum (blue marking) and 5 ampoules per 1 ml of diluted whey (1: 100) (red marking).


Containing specific immunoglobulins, the protein fraction of blood serum is hyperimmunized by diphtheria toxoid of horses; Purified and concentrated by the method of peptic digestion and salt fractionation. It is a clear or slightly opalescent colorless or yellowish liquid with no precipitate.

Pharmachologic effect

Mode of action - Detoxification.

Neutralizes toxins of diphtheria bacteria.

Indication of the drug Serum antidiphtericum equinum purificatum cocentratum liquidum


Side effects

In rare cases, allergic reactions, serum sickness.

Dosing and Administration

IM, in the region of the upper third of the antero-anterior surface of the thigh or buttock. The course of treatment is individual and depends on the severity of the disease.

Precaution measures

Before the introduction of serum, it is necessary to prepare anti-shock therapy. Opening of ampoules and the procedure for administering the drug are carried out with strict adherence to aseptic and antiseptic rules.

Storage conditions of the drug Serum antidiphtericum equinum purificatum cocentratum liquidum

In a dry, the dark place at a temperature of 2-8 C. The opened ampoule is stored, covered with a sterile napkin, no more than 1 hour.

Keep out of the reach of children.

Shelf life of the drug Serum antidiphtericum equinum purificatum cocentratum liquidum

2 years.

Do not use after the expiry date printed on the package.

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