Instruction for use: Parlodel

Dosage form: tablets

Active substance: Amantadine*

ATX

N04BC01 Bromocriptine

Pharmacological groups:

Dopaminomimetics

Anti-Parkinsonics

Composition and release form

1 tablet contains bromocriptine mesylate 2.5 mg; In the package of 30 pcs.

Pharmachologic effect

Mode of action - hypoprolactinemic, dopaminomimetic.

Indications for the Parlodel®

Prolaktinzavisimye menstrual disorders and female infertility, polycystic ovarian syndrome, anovulatory cycles (in addition to antiestrogens), premenstrual syndrome, hyperprolactinemia in men prolactinomas, acromegaly, suppression of lactation (for medical reasons), postpartum breast engorgement beginning postnatal mastitis, mastalgia And other forms of benign breast diseases, Parkinson's disease.

Contraindications

Hypersensitivity, malignant mammary tumors, hypertension (uncontrolled, during pregnancy, puerperium), coronary artery disease and other severe cardiovascular disease, mental illness (including history).

Side effects

Dry mouth, nausea, vomiting, constipation, dizziness, headache, drowsiness, weakness, confusion, agitation, hallucinations, dyskinesia, leg muscle cramps, cold upper and lower extremities, orthostatic hypotension, collapse, nasal congestion, loss of hair, Allergic skin reactions. Prolonged treatment of Parkinson's patients with high doses - pleural effusion, pleural, pulmonary or retroperitoneal fibrosis. In pregnant women, in rare cases, we observed the development of hypertension, myocardial infarction, seizures, stroke, mental disorders.

Interaction

Macrolides can increase the concentration in the plasma. Tolerance decreases against the background of alcohol.

Dosing and Administration

Inside, with food. At 1.25-40 mg per day.

Precautionary measures

In the postpartum period, it is not recommended to combine with vasoconstrictive drugs or ergot alkaloids. It is necessary to periodically monitor blood pressure; If hypertension develops, severe headache, visual impairment or neurointoxication symptoms, treatment is discontinued. Special care must be taken when driving vehicles or working with machinery. Since Parlodel can restore reproductive function of women of childbearing age who do not want pregnancy, you should consult with regard to a reliable method of contraception. Care must be taken with a stomach ulcer (including in an anamnesis). With long-term (for several years) application of high doses of parlodela in patients with parkinsonism, there is a risk of developing retroperitoneal fibrosis. If a diagnosis of fibrotic changes in the retroperitoneal region is established or there is a suspicion of such changes, treatment with Parlodel should be discontinued.

Storage conditions of the drug Parlodel

In the dark place at a temperature below 25 ° C.

Keep out of the reach of children.

Shelf life of the drug Parlodel

3 years.

Do not use after the expiry date printed on the package.