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Phenazepam is a highly tranquilizer. By the force of tranquilizing and anxiolytic (antianxiety) action is superior to other benzodiazepine tranquilizers and abenzodiazepinovye; It has also expressed an anticonvulsant, muscle relaxant (muscle-relaxing) and sedative effect. When applied together with drugs and opioid drugs are synergies depressing effect on the central nervous system.

Anxiolytic (tranquilizer) benzodiazepine. It has anxiolytic, sedative-hypnotic, anticonvulsant and central muscle relaxant effect.

It increases the inhibitory effect of GABA in the transmission of nerve impulses. It stimulates benzodiazepine receptors located in the allosteric center of postsynaptic GABA receptors ascending activating reticular formation of the brain stem; reduces the excitability of the subcortical structures of the brain (the limbic system, thalamus, hypothalamus), polisinapticheskie inhibits spinal reflexes.

The anxiolytic effect is due to the influence on the amygdala of the limbic system and manifests itself in the reduction of emotional stress, easing anxiety, fear, anxiety.

Sedation due to the influence on the reticular formation of the brain stem and the nonspecific thalamic nuclei and manifested a decrease in symptoms of neurotic origin.

On the productive psychotic symptoms genesis (acute delusional, hallucinatory, affective disorders) has practically no effect, it is rarely observed decrease in affective intensity, delusional disorders.

Hypnotic effects associated with inhibition of the cells of the reticular formation of the brain. Reduces emotional effects, autonomic and motor stimuli that disturb sleep.

Anticonvulsant action is realized by increasing presynaptic inhibition suppresses the spread of seizure pulse, but does not eliminate the excited state of the hearth.

Central muscle relaxant effect is due to inhibition of polysynaptic spinal afferent inhibitory ways (to a lesser extent - and monosynaptic). Perhaps, and direct inhibition of motor nerve and muscle function.

Phenazepam appoint:

  • at various neurotic, neurosis, psychopathic and psychopathic states, accompanied by anxiety, fear, increased irritability, emotional lability.
  • with obsessions, phobias hypochondriacal syndromes (including those resistant to the action of other tranquilizers)
  • with psychogenic psychoses, panic reactions, etc., since it removes the state of anxiety and fear,
  • for relief (removal) of alcohol withdrawal and delirium (state, resulting from the sudden discontinuation of alcohol)
  • as an anticonvulsant and hypnotic,
  • for sedation during preparation for surgical operations.


Hypersensitivity (including to other benzodiazepines), coma, shock, myasthenia gravis, angle-closure glaucoma (acute onset or predisposition), acute alcohol poisoning (with the weakening of vital functions), narcotic analgesics and sleeping drugs, severe COPD (possibly increasing respiratory failure) , acute respiratory failure, severe depression (suicidal tendencies may emerge); pregnancy (especially the I trimester), lactation, age 18 years (safety and effectiveness are not determined).

C care. Hepatic and / renal failure, cerebral and spinal ataxia, drug dependency history, the propensity to abuse drugs, hyperkinesis, organic brain disease, psychosis (possible paradoxical reactions), hypoproteinemia, sleep apnea (or suspected), advanced age.


Symptoms: severe drowsiness, prolonged confusion, decreased reflexes, prolonged dysarthria, nystagmus, tremor, bradycardia, dyspnea or shortness of breath, decreased blood pressure, coma.

Treatment: gastric lavage, activated charcoal. Symptomatic therapy (maintenance of respiration and blood pressure), administration of flumazenil (in the hospital). Hemodialysis - is ineffective.

Suggested Use:

When sleep disorders - 0.5 mg for 20-30 minutes before bedtime.

For the treatment of nevpoticheskih, psychopathic, and psihopatopodobnyh initial dose - 0.5-1 mg 2-3 times a day. After 2-4 days in view of efficacy and tolerability, the dose can be increased to 6.4 mg / day.

In severe agitation, fear, anxiety, treatment is initiated with a dose of 3 mg / day, quickly increasing the dose to produce a therapeutic effect.

In the treatment of epilepsy - 2.10 mg / day.

For the treatment of alcohol withdrawal - 2-5 mg / day.

The average daily dose - 1.5-5 mg, it is separated into 2-3 doses, usually 0.5-1 mg in the morning and afternoon, and 2.5 mg at night. In neurological practice for diseases with muscle hypertonicity appoint 2-3 mg 1-2 times a day.

The maximum daily dose - 10 mg.

In order to avoid the development of drug dependence at course treatment duration Phenazepam application is 2 weeks (in some cases the duration of treatment can be increased up to 2 months). If you cancel Phenazepam reduce the dose gradually.


  • Comes in original packaging. Item is brand new and unopened.


  • Keep away from direct sunlight.
  • Keep locked and away from children.
  • Store in dry place at room temperature.
  • Do not exceed storage temperature higher than 25 C

Important notice- the outer box design may vary before prior notice!


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