Instruction for use: Ephedrine (Ephedrinum)
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Chemical rational name: [R- (R *, S *)] - alpha- [1- (methylamino) ethyl] benzenemethanol (and hydrochloride)
Pharmacotherapeutic group:
Sympathomimetic drug
Hypertensive agents
CodeCAS 299-42-3
Characteristics substance of Ephedrine
Ephedrine - an alkaloid contained in various kinds of ephedra (Ephedra L.), family efedrovye (Ephedraceae).
Ephedrine hydrochloride - white needles and white crystalline powder bitter taste. Easily soluble in water (1: 5), soluble in alcohol (1:14), is practically insoluble in ether and chloroform.
The nosological classification (ICD-10)
G47.4 Narcolepsy and cataplexy
H599 * Diagnosis / eye disease diagnostics
I95 Hypotension
J30 Vasomotor and allergic rhinitis
J45 Asthma
L50 Urticaria
R32 Urinary incontinence unspecified
T40 Poisoning by drugs and psychodysleptics [hallucinogens]
T42.7 Poisoning by anticonvulsants, sedatives and hypnotics unspecified
T78.4 Allergy, unspecified
Z100 * CLASS XXII Surgical practice
Pharmacological Properties of EphedrinePharmachologic effect
vasoconstrictor, hypertensive, a bronchodilator, hyperglycemic, psychostimulant.
It stimulates alpha and beta-adrenergic receptors, inhibits the activity of MAO and catecholamine-ortometil transferase. It has a positive ino, chrono-, Drome and batmotroponoe action.
Indications for Ephedrine
Bronchial asthma, hay fever, urticaria, serum sickness and other allergic diseases, rhinitis, hypotension (surgery, spinal anesthesia, trauma, hemorrhage, infectious diseases, hypotension, etc.), Narcolepsy, poison pills and drugs, enuresis; locally - as a vasoconstrictor, for mydriasis (for diagnostic purposes).
Contraindications for Ephedrine
Hypersensitivity, insomnia, hypertension, atherosclerosis, organic heart disease, hyperthyroidism.
Side effects of Ephedrine
Light tremors, palpitations (15-30 min after ingestion); sleep disturbances, increased blood pressure, nervous agitation, tremor, urinary retention, loss of appetite, vomiting, sweating, insomnia, rashes.
special instructions
You should not assign ephedrine and preparations containing it at bedtime.