Instruction for use: Berlinsulin H Normal pen

ATX Code A10AB01 Insulin human

Active substance Insulin soluble [human biosynthetic]

Pharmacological group

insulins

Nosological classification (ICD-10)Z31.1 Artificial insemination

E10 Insulin-dependent diabetes mellitus

Decompensation of carbohydrate metabolism, Diabetes mellitus, Diabetes insulin sugar, Diabetes mellitus type 1, Diabetic ketoacidosis, Insulin-dependent diabetes, Insulin-dependent diabetes mellitus, Coma hyperosmolar non-ketoacidotic, Labile form of diabetes mellitus, Violation of carbohydrate metabolism, Type 1 diabetes mellitus, Type I diabetes mellitus, Insulin-dependent diabetes mellitus, Type 1 diabetes mellitus

E11 Non-insulin-dependent diabetes mellitus

Acetonuric diabetes, Decompensation of carbohydrate metabolism, Diabetes insulin-independent sugar, Diabetes sugar type 2, Type 2 Diabetes, Non-insulin-dependent diabetes, Non-insulin dependent diabetes mellitus, Non-insulin-dependent diabetes mellitus, Insulin resistance, Insulin resistant diabetes mellitus, Coma lactobacillus diabetic, Violation of carbohydrate metabolism, Type 2 diabetes mellitus, Diabetes mellitus type II, Diabetes mellitus in adulthood, Diabetes mellitus in old age, Diabetes insulin-independent, Diabetes mellitus type 2, Sugar insulin-independent diabetes type II

Composition and form of release

1 ml of solution for injection contains human insulin 100 U; In cartridges of 1.5 ml, in a box of 5 pcs.

pharmachologic effect

Pharmacological action - hypoglycemic.

Interacts with a specific receptor of the plasma membrane and penetrates into the cell, which activates the phosphorylation of cellular proteins, stimulates glycogen synthase, pyruvate dehydrogenase, hexokinase, inhibits fat lipase and lipoprotein lipase. In combination with a specific receptor facilitates the penetration of glucose into cells, enhances the absorption of glucose by tissues and promotes its conversion into glycogen. Increases the glycogen reserve in muscles, stimulates the synthesis of peptides.

Clinical Pharmacology

It is a preparation of quick and short action. The maximum effect develops in 1-3 hours and lasts 6-8 hours.

indications

Diabetes mellitus type I and II (all forms), diabetic coma.

Dosing and Administration

Usually the dose is given p / k (can be in / in) for 10-15 minutes before meals. With each injection, the injection site is changed. The daily dose is usually administered in the form of several single doses (in 3-4 doses).

storage Conditions

In a cool place, at a temperature of 2-8 ° C (do not freeze). In a cool place, at a temperature of 2-8 ° C, protect from freezing. After the cartridge is inserted into the injection device - in a place protected from direct sunlight, at temperatures below 30 ° C (but not in the refrigerator).

Keep out of the reach of children.

Shelf life

2 years. After the cartridge is inserted into the injection device - 28 days.

Do not use after the expiry date printed on the package.