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Ocumed eye drops 0.5% 5ml

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Ocumed (Okumed) eye drops - lowering intraocular pressure in certain types of glaucoma and with ocular hypertension. Timolola maleate, the main active substance of the drug, provides a quick and lasting effect.

Non-selective beta-blocker for topical application in ophthalmology. Has no internal sympathomimetic and membrane-stabilizing activity.

The drug reduces both normal and increased intraocular pressure by reducing the formation of intraocular fluid. Does not affect the size of the pupil and accommodation.

The effect of the drug manifests itself 20 min after instillation in the conjunctival sac. The maximum decrease in intraocular pressure develops after 1-2 hours and persists for 24 hours.

Pharmacokinetics

Suction

With topical application timolol quickly penetrates through the cornea.

After instillation of eye drops Cmax timolol in the aqueous humor of the anterior chamber of the eye is achieved in 1-2 hours.

In a small amount enters the systemic bloodstream by absorption through the vessels of the conjunctiva, the nasal mucosa and the lacrimal tract.

Excretion

Metabolites of timolol are excreted mainly by the kidneys.

Pharmacokinetics in special clinical cases

In newborns and young children, Cmax in blood plasma significantly exceeds that of adults.

Indications:

  • Increased intraocular pressure (ophthalmic hypertension).
  • Open angle glaucoma.
  • Secondary glaucoma.
  • To reduce intraocular pressure in closed-angle glaucoma (as an additional tool in combination with miotics).
  • Congenital glaucoma (with insufficient other therapeutic measures).

Contraindications:

  • Bronchial asthma or other severe chronic obstructive airway disease.
  • Sinus bradycardia.
  • AV-blockade II and III degree.
  • Acute congestive heart failure.
  • Severe chronic heart failure (NYHA III and IV functional class).
  • Cardiogenic shock.
  • Allergic reactions with generalized skin rashes.
  • Atrophic rhinitis.
  • Dystrophic diseases of the cornea.
  • Newborn period.
  • Hypersensitivity to the components of the drug.

With caution appoint the drug to patients with:

  • Pulmonary insufficiency.
  • Emphysema of the lungs.
  • Severe cerebrovascular insufficiency.
  • Heart failure (I and II functional class according to NYHA classification).
  • Sinoatrial blockade.
  • Arterial hypertension.
  • Diabetes mellitus.
  • Hypoglycemia.
  • Thyrotoxicosis.
  • Myasthenia.
  • Reye's Syndrome.
  • With the simultaneous administration of other beta-blockers.
  • Children.

Special instructions:

The patient should be warned about the need for regular measurement of intraocular pressure and examination of the cornea, as well as the need to stop using the drug and consult a doctor if side effects occur.

When wearing soft contact lenses, Ocumed eye drops should not be used. the preservative included in their composition can be deposited in soft contact lenses and have an adverse effect on the eye tissue.

Rigid contact lenses should be removed before instillation of the drug and set them again after 15 minutes.

When transferring patients to Ocumed treatment, correction of refraction may be necessary (after the disappearance of the effects of previously used myotics).

Ocumed must be discontinued 48 hours before surgery with general anesthesia.

Ocumed should not be used simultaneously with antipsychotic (antipsychotics) and anxiolytic (tranquilizers) drugs.

During the use of the drug is not recommended to drink alcohol (perhaps a sharp decrease in blood pressure).

Use in Pediatrics

Sufficient experience in the use of the drug in children is not, therefore, the prescription of the drug is possible only in cases when the intended use of therapy exceeds the potential risk of side effects.

Impact on the ability to drive vehicles and manage mechanisms

Immediately after application of the drug, it is possible to reduce the clarity of vision and slow the psychomotor reactions, which can reduce the ability to engage in potentially dangerous activities that require increased attention.

Suggested Use:

Adults and children over 10 years of age

Instilled 1 drop into the conjunctival sac of the affected eye 2 times / day, with insufficient effectiveness - 1 drop (eye drops 0.5%) 2 times / day. With the normalization of intraocular pressure, the maintenance dose is 1 drop 1 time / st.

Children under 10 years

Assign 1 drop (eye drops 0.25%) 2 times / day.

The drug is intended for long-term use.

The patient should be warned that only a doctor can change the dose or temporarily cancel the drug.

Packaging:

  • Comes in original packaging. Item is brand new and unopened.

Storage:

  • Keep away from direct sunlight.
  • Keep locked and away from children.
  • Store in dry place at room temperature.
  • Do not exceed storage temperature higher than 25 C

Important notice- the outer box design may vary before prior notice!

 

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