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Instructions

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Instructions / Instruction for use: Tetrazepam

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The Latin name of the substance Tetrazepam

Tetrazepamum (genus. Tetrazepami)

Chemical name

7-Chloro-5- (1-cyclohexen-1-yl) -1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one

Gross formula

C16H17ClN2O

Pharmacological groups:

Means that affect neuromuscular transmission

Anxiolytics

The nosological classification (ICD-10)

G24.3 Spasmodic torticollis: Spasmodic torticollis

G54.1 Lesions of the lumbosacral plexus: Lumbosacral radiculitis; Neuralgia of radicular origin; Pathology of the spine; Radiculitis of the lumbosacral; Radiculoneuritis

M15-M19 Osteoarthritis

M45 Ankylosing spondylitis: Ankylosing spondylarthrosis; Marie-Strumpel disease; Ankylosing spondylitis; Ankylosing spondylitis; Pain syndrome in acute inflammatory diseases of the musculoskeletal system; Pain syndrome in chronic inflammatory diseases of the musculoskeletal system; Bechterew's disease; Ankylosing spondylitis; Diseases of the spinal column; Rheumatic spondylitis; Bechterew-Marie-Strumpel disease

M54.3 Sciatica: Ischialgia; Neuralgia of the sciatic nerve; Sciatic neuritis

M54.5 Pain in the lower back: Pain in the lower back; Pain in the lower back; Lumbar pain; Lumbalia; Painful conditions of the spinal column; Back pain; Lower Back Pain Syndrome

M60 Myositis: Myositis; Fibrositis; Fibromyositis; Inflammatory disease of soft tissues

M62.4 Contracture of muscle: Neurological contractures with spasms; Muscular contracture

M65 Synovitis and tendosynovitis: Acute tenosynovitis; Tendovaginitis (tenovaginitis); Tendosinovit (tenosynovitis); Tendovaginitis; Osteoarthritis in musculo-articular diseases; Inflammatory disease of soft tissues; Nonspecific tenosynovitis; Tenosynovit; Tendosinovit

M77.0 Medial epicondylitis: Epicondylitis medial; Epicondylitis; Epicondylitis traumatic medial

M77.1 Lateral epicondylitis: Epicondylitis lateral; Epicondylitis; Epicondylitis traumatic lateral

R25.2 Cramp and spasm: Muscle spasms in tetanus; Pain syndrome with smooth muscle spasms; Pain syndrome with smooth muscle spasms (renal and biliary colic, intestinal spasm, dysmenorrhea); Pain syndrome with spasms of smooth muscles of internal organs; Pain syndrome with spasms of smooth muscles of internal organs (renal and biliary colic, intestinal spasm, dysmenorrhea); Painful muscular spasm; Mimic spasms; Muscular spasticity; Muscle spasms; Muscular spasms of central origin; Muscular spasticity; Muscle spasm; Neurological contractures with spasms; Night cramps in the extremities; Nocturnal cramps in the legs; Night cramps calf muscles; Symptomatic convulsive state; Vesta Syndrome; Spasm of smooth muscles; Spasm of smooth vascular musculature; Spasm of muscles; Spasm of striated muscle due to organic diseases of the central nervous system; Skeletal muscle spasms; Spasms of smooth muscles of internal organs; Skeletal Muscle Cramps; Spastic states of striated musculature; Spasmodic pain syndrome; The spastic condition of smooth muscles; Spasticity of skeletal musculature; Muscle cramp; Convulsions; Cramps of the calf muscles; Convulsions of central origin; Convulsive condition; Convulsive Syndrome; Convulsive status in children; Tonic convulsions; Cerebral spasmodic syndrome; clasp knife phenomenon

CAS Code

10379-14-3

Pharmacology

Pharmacological action - miorelaxing, central.

It stimulates benzodiazepine receptors, increases the sensitivity of GABA receptors to the mediator and enhances the inhibitory effect of GABA in the central nervous system. Reduces the excitability of the subcortical structures of the brain (anticonvulsant action), inhibits polysynaptic spinal reflexes. Reduces emotional tension, alleviates anxiety, fear, anxiety (anxiolytic and sedative action).

Passes through tissue barriers, including GEB. T1 / 2 - 14-16 hours.

Application of substance Tetrazepam

Muscular contracture, neurological contractures with spasms, torticollis, myositis, accompanied by severe pain syndrome, pain in the back and lower back, pain syndrome in the pathology of tendons (epicondylitis, tendovaginitis) and joints, for kinesiotherapy.

Contraindications

Hypersensitivity, respiratory failure, myasthenia gravis, pregnancy (especially I trimester), breast-feeding.

Application in pregnancy and lactation

Contraindicated in pregnancy (especially in the first trimester). For the duration of treatment, breastfeeding should be stopped.

Side effects of the substance Tetrazepam

Drowsiness, dizziness, euphoria, paradoxical reactions (irritability, aggressiveness), muscle weakness, ataxia, skin rash, itching; with a sharp cancellation: irritability, anxiety, myalgia, tremor, insomnia, nightmares, nausea, vomiting, convulsions, decreased reaction speed, fatigue.

Interaction

Strengthens (mutually) the effects of muscle relaxants, neuroleptics, tranquilizers, tricyclic antidepressants, alcohol, sedatives and hypnotics.

Routes of administration

Inside.

Precautions for the substance Tetrazepam

Do not use during work drivers of vehicles and people whose profession is associated with increased concentration of attention. For the duration of treatment it is necessary to refrain from drinking alcohol.