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Instruction for use: Rheopyrin

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ATX code N02BB53 Aminofenazone in combination with other drugs other than psycholeptics

Pharmacological group

Other non-narcotic analgesics, including non-steroidal and other anti-inflammatory drugs

Nosological classification (ICD-10)

G62 Other polyneuropathies

Polyneuritis, Polineuropathy, Inflammation of peripheral nervesG61 Inflammatory polyneuropathy

H20 Iridocyclitis

recurrent iritis, sympathetic iridocyclitis, Sluggish posterior uveitis, Sluggish posterior uveitis, Posterior uveitis, the posterior segment of the eye Iridocyclitis, Iridocyclitis and other uveitis, Irit, Keratoiridotsiklit, Acute iritis, uveitis, cycle of Acute iridocyclitis, Acute non-infectious uveitis

H30 Chorioretinal inflammation

Retinitis, Chorioretinitis, Central and peripheral chorioretinal dystrophy

I00-I02 Acute rheumatic fever

I30 Acute pericarditis

Pericarditis exudative, Pericarditis acute, Pericarditis exudate, Pericarditis is constrictive, Pericarditis, Exudative pericarditis, Constrictive pericarditis, Exudative-constrictive pericarditis, Pericarditis purulent

I31.0 Chronic adhesive pericarditis

Pericarditis chronic

M10 Gout

Exacerbation of gout, Acute articular attack with gout, Acute gouty attack, Gouty attack, Recurrent gout attacks, Chronic gout

M13.9 Arthritis, unspecified

Arthritis,Purulent arthritis (non-infectious), acute Arthritis,Pain in acute inflammatory diseases of the musculoskeletal system,Pain in chronic inflammatory diseases of the musculoskeletal system,The pain in osteoarthritis, Inflammation in osteoarthritis, Inflammatory arthropathy, Inflammatory and degenerative joint diseases, Inflammatory disease of the musculoskeletal system, Inflammatory joint disease, Inflammatory diseases of the musculoskeletal system, destructive arthritis, The disease of the musculoskeletal system, Diseases of the musculoskeletal system, Diseases of the musculoskeletal system and connective tissue, Infections musculoskeletal system, monoartrit, Non-infectious arthritis, rheumatic arthritis, Osteoarthritis, Acute inflammation of the musculoskeletal tissue, Acute inflammatory diseases of the musculoskeletal system, Acute inflammatory condition of the musculoskeletal system, Acute arthritis, Acute osteoarthritis, Post-traumatic osteoarthritis, Reactive arthritis, Chronic inflammatory diseases of the joints, Chronic arthritis, Chronic inflammatory arthritis, Chronic inflammation of the inner layer of the joint capsule, Chronic inflammation of the joint capsule,Chronic inflammatory disease of the joints, Exudative arthritis

M60 Myositis

Myositis, Fibrositis Fibromyositis, Inflammatory disease of soft tissues

M79.0 Other unspecified rheumatism

Degenerative rheumatic disease, Degenerative and rheumatic diseases of the tendons, Degenerative rheumatic diseases, Localized forms of rheumatism of soft tissues, Rheumatism, Rheumatism with a pronounced allergic component, Rheumatism of the articular and extraarticular, Rheumatic attack, Rheumatic complaints, Rheumatic diseases, Rheumatic disease of the spine, Relapses of rheumatism, Articular and extra-articular rheumatism, Articular and muscular rheumatism, Articular rheumatism, Articular syndrome with rheumatism, Chronic rheumatic pain, Chronic articular rheumatism, Rheumatoid diseases, Rheumatic diseases of the intervertebral disc

M79.2 Neurology and neuritis, unspecified

Pain syndrome with neuralgia, Brachialgia, Occipital and intercostal neuralgia, Neuralgia, Neuralgic pain, Neuralgia, Neuralgia of intercostal nerves,Neuralgia of the posterior tibial nerve, Neuritis, Neuritis traumatic, Neuritis, Neurological Pain Syndromes, Neurological contractures with spasms, Acute neuritis, Peripheral neuritis,Post-traumatic neuralgia,Severe pain of a neurogenic nature, Chronic neuritis, Essential neuralgia

N70 Salpingitis and oophoritis

Adnexitis, Inflammatory diseases of female genitalia, Inflammatory diseases of female genital organs, Infection of the genitals, Oophoritis, Acute adnexitis, Salpingitis, Salpingo-oophoritis, Chronic inflammatory diseases of the ovaries, Inflammation of the ovaries

N73.2 Parametritis and pelvic cellulitis, unspecified

Infections of pelvic fat, Pelvic cellulite, Parametritis, Pelvic cellulite

R52 Pain, not elsewhere classified

Pain syndrome of radicular origin, Pain syndrome of small and medium intensity of different genesis, Pain syndrome after orthopedic surgery, Pain syndrome in superficial pathological processes, Radicular pain in the background of osteochondrosis of the spine, Radicular pain syndrome, Pleural pain, Chronic pain

Composition and form of release

5 ml of solution for injection contains 750 mg of sodium phenylbutazone and aminophenazone; in ampoules of dark glass of 5 ml, in a box of 5 ampoules.

1 dragee - 125 mg of active substances; in a contour acheikova packing 10 pcs., in a box 2 packages.

pharmachologic effect

Pharmacological action - anti-inflammatory, antipyretic, analgesic.

Inactivates cyclooxygenase, inhibits the biosynthesis of PG, prevents the formation of endoperexides and free radicals, inhibits lipid peroxidation; reduces the activating effect of PGE2 and PGI2 on the perception of pain and pain transmission, on the excitability of neurons in the heat-regulating structures.


Non-infectious arthritis (acute rheumatoid arthritis, acute gouty arthritis, etc.), pain syndrome, inflammatory diseases of the spine, extraarticular soft tissues, adnexitis, parametritis, pericarditis, polyserositis, neuralgias, polyneuritis, iritis, retinitis.


Hypersensitivity, heart rhythm disturbances, heart defects, cardiomyopathy, kidney and liver diseases, peptic ulcer of the stomach and duodenum, edematous syndrome, oppression of hematopoiesis; epilepsy (even suspicion) - parenteral use.

Side effects

Delayed water and sodium, leukopenia, glucosuria, hematuria, drowsiness, pain, aseptic abscess (at the injection site).

Dosing and Administration

Inside - 4-6 pills a day.

Intramuscularly (intramuscularly) (deep into the large gluteus muscle with a long needle, slowly, for 1-2 minutes) - 5 ml daily or every other day (with an acute pain syndrome).

Children aged 7-14 years inside - 0.5-1 tablets 3 times a day or deep in / m - 0.5-1 ml daily or every other day.

Precautionary measures

Due to the increased risk of side effects, children are prescribed only in extreme cases and only in a hospital with constant monitoring of blood, urine, liver function. With prolonged treatment, it is necessary to determine the number of leukocytes every week.

storage Conditions

At a temperature of 15-25 ° C.

Keep out of the reach of children.

Shelf life

solution for injection - 3 years.

dragees - 5 years.

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