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DR. DOPING

Instructions

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Instruction for use: Ortophenum

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Active substance Diclofenac

ATX Code M02AA15 Diclofenac

Pharmacological group

NSAIDs - Derivatives of acetic acid and related compounds

Nosological classification (ICD-10)

M05 Seropositive rheumatoid arthritis

Rheumatoid arthritis seropositive

M79.0 Other unspecified rheumatism

Degenerative rheumatic disease, Degenerative and rheumatic diseases of the tendons, Degenerative rheumatic diseases, Localized forms of rheumatism of soft tissues, Rheumatism, Rheumatism with a pronounced allergic component, Rheumatism of the articular and extraarticular, Rheumatic attack, Rheumatic complaints, Rheumatic diseases, Rheumatic disease of the spine, Relapses of rheumatism, Articular and extra-articular rheumatism, Articular and muscular rheumatism, Articular rheumatism, Articular syndrome with rheumatism, Chronic rheumatic pain, Chronic articular rheumatism, Rheumatoid diseases, Rheumatic diseases of the intervertebral disc

R52.2 Other constant pain

Pain syndrome, rheumatic origin, Pain at vertebral lesions, Pain in the chamber, Pain for burns, Pain syndrome weak or moderate, Perioperative pain,Moderate to severe pain, Moderately or weakly expressed pain syndrome, Moderate to severe pain, Ear pain of otitis, Neuropathic pain, neuropathic pain

Composition and form of release

1 g of ointment contains diclofenac sodium 20 mg; in tubes of 30 grams, in a cardboard bundle 1 tube.

pharmachologic effect

Pharmacological action - anti-inflammatory, analgesic.

Inhibits the synthesis of PG; reduces pain, swelling and flushing of tissues.

Pharmacokinetics

Well absorbed through the skin into the subcutaneous tissue for 5 minutes. Binding to plasma proteins up to 99%. It penetrates into the synovial fluid, where the concentration remains unchanged for 7 hours. Conjugated metabolites are secreted mainly through the kidneys, a smaller part is excreted with feces. The analgesic effect is achieved 30-60 minutes after application of the ointment and remains for 2.5-5 hours, the maximum effect develops after 1-2 hours.

Indications

Inflammatory and degenerative joint diseases; rheumatism of soft tissues; traumatic bruises, sprain of ligaments, muscles and tendons; inflammatory edema of soft tissues, soreness of muscles and joints, caused by heavy physical stress.

Contraindications

Hypersensitivity, incl. to other NSAIDs; peptic ulcer of the stomach and duodenum in the phase of exacerbation; allergic asthma, rhinitis, urticaria, children under 6 years old.

pregnancy and lactation

Contraindicated (especially in the III trimester of pregnancy). For the period of treatment, nursing mothers should give up breastfeeding.

Side effects

Allergic skin reactions (burning, redness); with long-term use and / or use in large amounts - systemic side effects, characteristic for NSAIDs.

Dosing and Administration

Externally, 2-4 g of ointment is applied a thin layer on the painful area 3-4 times a day. The maximum daily dose is 8 g. The course (individual) is 1-14 days.

Precautionary measures

Do not apply to damaged skin and mucous membranes.

storage Conditions

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

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