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DR. DOPING

Instructions

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Instruction for use: Microser

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Dosage form: Drops for oral administration; tablets

Active substance: Betahistine*

ATX

N07CA01 Betahistine

Pharmacological groups:

Angioprotectors and microcirculation correctors

Histaminomimetics

The nosological classification (ICD-10)

H81 Violations of the vestibular function: Vestibulopathy; Labyrinthine-vestibular disorders; Cochleovestibular syndrome; Vestibular disorder; Vestibular abnormalities; Vertigo of labyrinth origin; Violation of microcirculation in the labyrinth; Cochleovestibular disorder; Cohleo-vestibular impairment of ischemic nature; Disorders of the vestibular apparatus

H81.0 Meniere's disease: Meniere's syndrome/ disease; Meniere's disease; Meniere's syndrome; Labyrinth dropsy; endolymphatic hydrops

Composition and release form

1 tablet contains betahistine dihydrochloride 8 mg; In the box 5 blisters for 10 pcs.

100 ml drops for oral administration - 1.25 g; In bottles of 30 ml.

Pharmachologic effect

Mode action - improving microcirculation, histamine-like.

It restores blood flow in the microcirculatory bed, inhibits diamino oxidase, blocks the disintegration of endogenous histamine and neuronal transmission in the polysynaptic neurons of the lateral nuclei of the vestibular nerve at the level of the stem of the brain, affects precapillary sphincters, increases precapillary blood flow.

Pharmacokinetics

Quickly and fully absorbed. Achieves peak concentration in the blood by the third hour. Passes histohematological barriers and penetrates into tissues. It is exposed to biotransformation within a day, most of it is converted to 2-pyridylacetic acid. Virtually completely excreted in the urine.

Indication of the preparation Microser

Pathological conditions caused by a violation of microcirculation in the labyrinth: dizziness, Meniere's syndrome, etc.

Contraindications

Hypersensitivity, peptic ulcer in the active phase, pheochromocytoma, children's age.

Application in pregnancy and breastfeeding

Pregnant women should be prescribed only in cases of extreme necessity.

Side effects

Nausea, headache, manifestations of idiosyncrasy.

Interaction

The effect is weakened by antihistamines.

Dosing and Administration

Inside - 2-4 tablets. Per day, or 16 drops, diluted in water, 2-4 times a day, preferably with meals.

Overdose

In case of an overdose, gastric lavage and appropriate medical interventions are recommended. There is no specific antidote.

Storage conditions of the drug Microser

In the dark place at a temperature of no higher than 25 į C.

Keep out of the reach of children.

Shelf life of the drug Microser

Tablets 8 mg - 5 years.

Drops for oral administration 12.5 mg / ml - 3 years.

Do not use after the expiry date printed on the package.

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