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Afobazol 10mg 60 pills

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Afobazol (Afobazole) - selective non-benzodiazepine anxiolytic. Acting on the σ1-receptors in nerve cells of the brain, GABA Afobazol stabilizes / benzodiazepine receptors and restores their sensitivity to inhibition by endogenous mediators. Afobazol also increases the bioenergy potential of neurons and has a neuroprotective effect: restores and protects nerve cells.

The drugs are sold mainly in the form of a combination of anxiolytic (anti-anxiety) and a light stimulus (activating) effects. Afobazol reduces or eliminates anxiety (concern, foreboding, fear), irritability, tension (fearfulness, tearfulness, anxiety, inability to relax, insomnia, fear), depressed mood, somatic symptoms of anxiety (muscular, sensory, cardiovascular, respiratory , gastrointestinal symptoms), vegetative disorders (dry mouth, sweating, dizziness), cognitive disorders (difficulty concentrating, impaired memory), including arising from stress disorders (disorders of adaptation). Especially shows the use of the drug in patients with predominantly asthenic personality traits as alarming suspiciousness, insecurity, increased vulnerability and emotional lability, tendency to emotional and stress reactions.

The effect of the drug develops 5-7 days of treatment. The maximum effect is achieved by the end of the 4th week of treatment and persists after the end of treatment an average of 2.1 weeks. Afobazol causes muscular weakness, drowsiness and has no negative effects on concentration and memory. If its application is not formed addiction, drug dependency and does not develop "cancellation" syndrome.

Indications Afobazol:

Afobazol used in adults with anxiety:

  • Generalized anxiety disorder;
  • Neurasthenia;
  • Adjustment disorder;

Patients with various medical conditions:

  • bronchial asthma;
  • Irritable bowel syndrome;
  • Systemic lupus erythematosus;
  • Coronary artery disease;
  • hypertonic disease;
  • Arrhythmias;
  • Dermatological, oncological and other diseases.

In the treatment of:

  • Sleep disorders associated with anxiety;
  • Soldier's heart;
  • Premenstrual syndrome;
  • Alcohol withdrawal syndrome;
  • To facilitate syndrome "cancel" for smoking cessation.

Afobazol does not react with ethanol and does not affect the hypnotic effect of thiopental. It enhances the anticonvulsant effect of carbamazepine. It is strengthening the anxiolytic effect of diazepam.

Following oral administration Afobazol well and rapidly absorbed from the gastrointestinal tract.

Afobazol intensively distributed by well-vascularized organs, for it is characterized by a rapid transfer from the central pool (blood plasma) in the peripheral (highly vascularized organs and tissues).

Afobazol exposed to the effect of the first passage through the liver, the main directions of the metabolism is the hydroxylation of the aromatic ring of the benzimidazole cycle and oxidation by a morpholino moiety.

The drug has no negative influence on the driving of vehicles and the implementation of potentially hazardous activities that require high concentration and speed of psychomotor reactions.

Suggested Use:

After a meal.

The optimal single dose - 10 mg daily - 30 mg for 3 doses distributed over the day. The duration of a course of the drug is 2-4 weeks.

If necessary, on doctor's advice, the daily dose can be increased to 60 mg, and the duration of the treatment and 3 months.

Side effects:

Allergic reactions are possible. Rarely - headache, which usually resolves on its own and does not require the abolition of drug.

Packaging:

  • Comes in original packaging. Item is brand new and unopened.

Storage:

  • Keep away from direct sunlight.
  • Keep locked and away from children.
  • Store in dry place at room temperature.
  • Do not exceed storage temperature higher than 25 C

Important notice - the outer box design may vary before prior notice!

 

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