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Instructions

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Instruction for use: Miansan

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Dosage form: tablets

Active substance: Mianserin*

ATX

N06AX03 Mianserin

Pharmacological groups:

Antidepressant

The nosological classification (ICD-10)

F32 Depressive episode: Adynamic subdepression; Astheno-adynamic subdepressive states; Asthenoadressive disorder; Astheno-depressive disorder; Asthenodepressive state; Astheno-depressive state; Major Depressive Disorder; Vyaloapatichesky depression with retardation; Double Depression; Depressive pseudodement; Depressive illness; Depressive mood disorder; Depressive disorder; Depressive mood disorder; Depressive state; Depressive disorders; Depressive syndrome; Depressive syndrome larviated; Depressive syndrome in psychoses; Depressed masks; Depression; Depression Depletion; Depression with the phenomena of inhibition within the framework of cyclothymia; Depression is smiling; Involutional depression; Involutionary melancholy; Involutional depression; Manic-depressive disorder; Masked Depression; Melancholic Attack; Neurotic depression; Neurotic depression; Shallow Depression; Organic depression; Organic depressive syndrome; Simple depression; Simple melancholic syndrome; Psychogenic depression; Reactive depression; Reactive depression with moderate psychopathological symptoms; Reactive depressive states; Reactive depression; Recurrent depression; Seasonal depressive syndrome; Severostatic depression; Senile Depression; Symptomatic Depression; Somatogenic depression; Cyclotymic depression; Exogenous depression; Endogenous depression; Endogenous Depressive Conditions; Endogenous Depression; Endogenous depressive syndrome

F45.2 Hypochondriacal disorder: Hypochondriac and asthenoipochondrial condition; Hypochondria; Sesto-hypochondriacal disorders; Hosto-hypochondriacal disorders; Asthenoepochondrial phenomena; Hypochondriacal disorders; Hypochondriac neurosis; Hypochondriacal-senesthetic syndrome

Composition and release form

1 tablet contains 30 mg of myanserin; in blistere 14 pcs., in the box 1 blister.

Pharmachologic effect

Pharmacological action - antidepressant, hypnotic, sedative.

Stimulates adrenergic transmission in the brain due to blockade of presynaptic (blocking) adrenergic receptors.

Pharmacokinetics

Quickly absorbed. Cmax in the blood plasma is achieved after 3-4 hours. 96% of the plasma proteins bind. T1 / 2 - 24-32 h. 70% (partially in the form of metabolites) are excreted by the kidneys and intestines (8-28%).

Indications of Miansan

Depression (reactive, endogenous), caused by somatic diseases, involuntary melancholy.

Contraindications

Manic syndrome, a violation of the liver, an acute period of myocardial infarction, age (under 18 years).

Application in pregnancy and lactation

Assign with caution (unless the expected benefits exceed the potential risk).

Side effects

Drowsiness, hypomania, hypotension, impaired liver function, edema, gynecomastia, granulocytopenia, agranulocytosis, convulsions.

Interaction

Incompatible with MAO inhibitors, alcohol. Strengthens the effect of antihypertensive drugs and weakens - anticonvulsants.

Dosing and Administration

Inside, not liquid, at bedtime, 60-90 mg / day. The optimal dose is 60 mg / day.

Precautionary measures

During the period of treatment, careful monitoring of patients with hepatic, renal and heart failure, monitoring of blood sugar in patients with diabetes mellitus is recommended. During treatment, you can not drive a car and engage in activities that require increased attention and high reaction rates. When signs of infection, stomatitis, sore throat, you need to do a blood test.

Storage conditions for Miansan

At room temperature.

Keep out of the reach of children.

Shelf life of Miansan

3 years.

Do not use after the expiry date printed on the package.

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