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Instruction for use: MarcaineSpinal

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Dosage form: solution for injection

Active substance: Bupivacaine


N01BB01 Bupivacaine

Pharmacological group:

Local Anesthetics

Composition and release form

Solution for injection 1 ml

bupivacaine 5 mg

Sodium monochloride 8 mg

auxiliary substances: sodium hydroxide and / or hydrochloric acid for pH correction; water for injections

in ampoules of 4 ml; in a cardboard box 5 pcs.

Dosing and Administration

Spinal administration of the drug is carried out only after a clear definition of the subarachnoid space with a lumbar function. Do not administer the drug until a clear spinal fluid is released from the spinal needle (spontaneously or aspirated). The index of ineffective spinal anesthesia is 1-5%. One of the reasons is a disruption of the local anesthetic distribution in the intrathecal space due to its accumulation in the caudal part or in the area with a difficult communication with the main cerebrospinal space. In such cases, sufficient blockade can be achieved by changing the position of the patient's body. If additional blockade is required, then it is performed at a different level using a smaller volume of local anesthetic. It is allowed to conduct no more than one additional attempt.

Clinical and side effects with spinal administration of bupivacaine in a dose above 20 mg have not been studied.

In adults, the background of spinal blockade usually develops hypotension.

The development of anesthesia is slower than with lidocaine, the duration of anesthesia is from 60 to 120 min.

Recommended doses for Marcain Spinal:

There are large individual differences in the nature of the distribution, the beginning and duration of the drug, so the recommended dosages given in the table should be considered as indicative.

Level of anesthesia Puncture area Position of the patient's body Dose Start of action, min Duration, h
ml mg
L1 L3/4/5 Horizontal 2-3 10-15 5-8 2-3
Indications: operations on the lower extremities, perineum, urological operations L2/3/4 Horizontal 3-4 15-20 5-8 3-4

Conditions for storing Marcaine Spinal

At a temperature of 2-25 ° C (do not freeze).

Keep out of the reach of children.

Shelf life of Marcaine Spinal

3 years.

Do not use after the expiry date printed on the package.

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