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Instruction for use: Immunoglobulin human antistaphylococcus

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Trade name of the drug – Immunoglobulinum antistaphylococcum humanum fluidum, Immunoglobulinum antistaphylococcum humanum fluidum

The Latin name of the substance Immunoglobulin human antistaphylococcus

Immunoglobulinum antistaphylococcum humanum (genus. Immunoglobulini antistaphylococci humani)

Pharmacological group of substances Immunoglobulin human antistaphylococcus:


Model clinical-pharmacological article 1

Characteristic. Concentrated solution of immunologically active protein fraction of blood plasma of healthy donors (tested for absence of surface antigen of hepatitis B virus and antibodies to HIV (1 and 2) and to hepatitis C virus) containing antibodies to staphylococcal exotoxin. Ig are isolated, purified and concentrated by ethanol fractionation at 0 ° C. Does not contain preservatives and antibiotics.

Pharmacotherapy. The active principle is antibodies that have a specific activity against staphylococcal exotoxin.

Indication. Infections of staphylococcal etiology.

Contraindications. Hypersensitivity (including to human blood products, in anamnesis); With severe sepsis - only anaphylactic shock in the history of the introduction of blood products.

Dosing. IM, in the upper outer square of the gluteus muscle. Before the injection, the ampoules from the preparations are kept for 2 hours at room temperature (18-22 ° C). In case of generalized staphylococcal infection, the minimum single dose is 5 IU / kg (for children under 5 years - not less than 100 IU); With focal infections, the minimum single dose is not less than 100 IU. The course of treatment is 3-5 injections, administered daily or every other day, depending on the severity of the disease and the therapeutic effect.

Side effect. Rarely - local reactions, hyperthermia up to 37.5 ° C, allergic reactions (up to anaphylactic shock).

Special instructions. The concentration of protein in the preparation is 9.5-10.5%.

After the administration of the drug, patients should be under medical supervision for 30 minutes. The cabinets should be equipped with anti-shock therapy.

Ig administration is recorded in established registration forms with the manufacturer's indication, serial number, date of manufacture, expiration date, date of administration, dose and nature of the response to administration.

Patients suffering from allergic diseases or having a history of allergic reactions with clinical symptoms are given antihistamine therapy; With immunopathological system diseases (blood diseases, connective tissue, nephritis, etc.) - against the background of appropriate therapy.

The drug is not suitable for use if the integrity of the ampoules or their labeling is violated, physical properties are changed (clouding, discoloration, a non-dissolving precipitate in the form of flakes), expiration date and storage conditions are not observed.

To prevent the formation of foam, the drug is drawn into the syringe with a needle with a wide lumen. The drug is not subject to storage after opening the ampoule.

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