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Instructions

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Instruction for use: Cytotec

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Dosage form: Tablets

Active substance: Misoprostol*

ATX

A02BB01 Misoprostol

Pharmacological group:

Prostaglandins, thromboxanes, leukotrienes and their antagonists

The nosological classification (ICD-10)

K25 Stomach ulcer: Helicobacter pylori; Pain syndrome with gastric ulcer; Pain syndrome with peptic ulcer of stomach and duodenum; Inflammation of the gastric mucosa; Inflammation of the mucosa of the gastrointestinal tract; Benign ulcer of the stomach; Disease of the stomach and duodenum, associated with Helicobacter pylori; Exacerbation of gastroduodenitis against ulcer disease; Exacerbation of peptic ulcer; Exacerbation of gastric ulcer; Organic GI disease; Peptic ulcer of the stomach and duodenum; Postoperative Stomach Ulcer; Recovering ulcers; Symptomatic Stomach Ulcers; Chronic inflammatory disease of the upper gastrointestinal tract associated with Helicobacter pylori; Helicobacter pylori eradication; Erosive-ulcerative lesions of the stomach; Erosive lesions of the stomach; Erosion of the gastric mucosa; Peptic Ulcer; Stomach ulcer; Stomach ulcer; Ulcerative lesions of the stomach; Symptomatic ulcers of the stomach and duodenum

K26 Ulcer of duodenum: Pain syndrome with duodenal ulcer; Pain syndrome with peptic ulcer of stomach and duodenum; Disease of the stomach and duodenum, associated with Helicobacter pylori; Exacerbation of peptic ulcer; Exacerbation of duodenal ulcer; Peptic ulcer of the stomach and duodenum; Recurrence of duodenal ulcer; Symptomatic ulcers of the stomach and duodenum; Helicobacter pylori eradication; Erosive-ulcerative lesions of the duodenum; Erosion-ulcerative duodenal lesions associated with Helicobacter pylori; Erosive lesions of the duodenum; Peptic ulcer disease of the duodenum; Ulcerative duodenal lesions

K27 Peptic ulcer of unspecified site: Perforation in peptic ulcer; Drug-induced gastrointestinal ulcer; Medication Ulcers; Peptic ulcer of the gastrointestinal tract; Peptic ulcer with Helicobacter pylori; Peptic Ulcers; Damage to the mucosa of the gastrointestinal tract caused by the intake of NSAIDs; Symptomatic gastrointestinal ulcer; Stress ulcer; Stress ulcer of the stomach; Stress damage to the mucosa; Stress ulcers; Stress ulcer of the duodenum; Stressed stomach ulcers; Stress ulcers of the digestive tract; Erosive-ulcerative lesions of the digestive tract; Erosion of the digestive tract; Erosion of the mucosa of the upper gastrointestinal tract; Erosion of the mucosa of the gastrointestinal tract; Gastric ulcer; Ulcer medication; Peptic ulcer; Postoperative ulcer; Stress ulcer; Ulcerous lesions of the digestive tract; Acute stress ulcer of the digestive tract; Symptomatic ulcers of the gastrointestinal tract; Complications of peptic ulcer

Y45 Adverse reactions in the therapeutic use of analgesic, antipyretic and anti-inflammatory agents

Composition and release form

1 tablet contains misoprostol 200 μg; In the blister 10 pcs., In the box 2 blisters.

Pharmachologic effect

Mode of action - antiulcer.

It is an analogue of endogenous PG E1, inhibits basal, stimulated and nocturnal secretion of gastric juice, reduces its volume and proteolytic activity. It prevents the development of erosive and ulcerative gastrointestinal lesions when administered with NSAIDs. Protects the gastric mucosa, promotes the healing of peptic ulcers.

Indication for the Cytotec

Peptic ulcer of the stomach and duodenum, ulcers caused by the use of NSAIDs (treatment and prevention).

Contraindications

Hypersensitivity, severe hepatic impairment, pregnancy.

Side effects

Abdominal pain, nausea, dyspepsia, flatulence, diarrhea (light forms), vomiting, constipation; Skin rash, headache, rarely - hypermenorrhea, menstrual disorders, convulsions (single cases in women in the pre- or post-menopausal period).

Dosing and Administration

Inside, during meals to treat ulcers (stomach, duodenal ulcers caused by NSAIDs) - 800 mcg per day in 2-4 doses for 4-8 weeks (primary course); For the prevention of NSAID-induced ulcers - 200 mcg 2-4 times a day.

Precautionary measures

Caution should be given to patients with hypotension.

Storage conditions of the drug Cytotec

In a dry place, at a temperature of no higher than 30 ° C.

Keep out of the reach of children.

The shelf life of the drug Cytotec

3 years.

Do not use beyond the expiration date printed on the package.

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