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Instruction for use: Clopixol Depot

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Dosage form: solution for intramuscular administration (oily)

Active substance: Zuclopenthixol*


N05AF05 Zuclopentixol

Pharmacological group:


The nosological classification (ICD-10)

F20 Schizophrenia: Schizophrenic Conditions; An exacerbation of schizophrenia; Schizophrenia; Chronic schizophrenia; Dementia praecox; Bleuler's disease; Psychotic discordant; Dementia early; The febrile form of schizophrenia; Chronic schizophrenic disorder; Psychosis of the schizophrenic type; Acute form of schizophrenia; Acute schizophrenic disorder; Cerebral Organic Insufficiency in Schizophrenia; Acute attack of schizophrenia; Schizophrenic psychosis; Acute schizophrenia; Sluggish schizophrenia; Sluggish schizophrenia with apathoabulic disorders; Acute stage of schizophrenia with agitation

F22 Chronic Delusional Disorders: Delusional Chronic Disorder; Delusional Disorders; Delusional syndrome; Paranoia; Chronic affective-delirious states

F30 Manic episode: Manic-depressive disorder; Manic agitation; Manic state; Manic conditions; Manic condition; Manic syndrome; Acute manic syndrome

F70-F79 Mental retardation

R44.3 Hallucinations, unspecified: Hallucinatory conditions; Hallucinations; Acute hallucinatory state; Chronic hallucinatory conditions

R45.1 Anxiety and agitation: Agitation; Anxiety; Explosive excitability; Internal stimulation; Excitability; Excitation; Excitation acute; Psychomotor agitation; Hyperexcitability; Motor excitement; Cessation of psychomotor agitation; Nervous excitement; Restlessness; Night trouble; Acute stage of schizophrenia with agitation; Acute mental agitation; Paroxysm of excitation; Overexcitation; Increased excitability; Increased nervous excitability; Increased emotional and cardiac excitability; Increased agitation; Mental arousal; Psychomotor agitation; Psychomotor agitation in psychoses; Psychomotor agitation of an epileptic nature; Psychomotor paroxysm; Psychomotor fit; Symptoms of Excitation; Symptoms of psychomotor agitation; The state of agitation; A state of anxiety; Excitation status; A state of heightened concern; The state of psychomotor agitation; Conditions of anxiety; Excitation conditions; The state of excitement in somatic diseases; Excitation level; Feelings of anxiety; Emotional arousal

R45.6 Physical aggressiveness: Aggressiveness; Aggressive states; Aggression; Aggressive behavior; Autoaggression

Composition and release form

1 ml of solution for injection contains zuclopentixola decanoate (in vegetable oil Viscoleo) 200 mg; in the package 1 or 10 ampoules per 1 ml.

1 ml solution for injection - 500 mg; in the package 5 ampoules of 1 ml.

Pharmachologic effect

Pharmacological action - antipsychotic, neuroleptic, sedative.

It blocks dopamine receptors of the brain.

Indications for the drug Clopixol Depot

Acute and chronic schizophrenia and other psychotic disorders, especially with hallucinations, paranoid delusions, impaired thinking; a state of agitation, increased anxiety, hostility, aggression (supportive therapy).


Acute poisoning with alcohol, barbiturates, opiates; comatose conditions.

Application in pregnancy and lactation

Contraindicated. Nursing mothers should stop breastfeeding.

Side effects

Possible extrapyramidal disorders, tardive dyskinesia, malignant neuroleptic syndrome, drowsiness, dizziness, dry mouth, discomfort, urinary retention, constipation, tachycardia, orthostatic hypotension, changes in hepatic samples.


Strengthens the effect of alcohol, barbiturates and other drugs, depressing the central nervous system, reduces - levodopa and other adrenergic substances. Weaken the hypotensive effect of guanethidine and its analogues. The risk of developing extrapyramidal disorders increases metoclopramide and piperazine. Can be mixed with Clopixol-Acuphase (co-injection).

Dosing and Administration

IM, in the upper outer quadrant of the gluteal region. Dosage and interval between injections are determined individually, in accordance with the patient's condition.

Storage conditions for Clopixol Depot

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life of Clopixol Depot

4 years.

Do not use after the expiry date printed on the package.

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