DR. DOPING

Instructions

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Instructions / Instruction for use: Anafranil SR

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Dosage form: tablets

Active substance: Clomipramine*

ATX

N06AA04 Clomipramine

Pharmacological groups:

Antidepressant [Antidepressants]

Composition and release form

Tablets, coated with a prolonged-action coating.

clomipramine hydrochloride 75 mg

auxiliary substances: calcium hydrophosphate dihydrate; polyacrylate dispersion 30%; calcium stearate; silicon dioxide colloidal anhydrous; hydroxypropyl cellulose; talc; titanium dioxide; polyoxyl 40-hydrogenated castor oil; iron oxide red

in blisters for 10 pcs .; in a pack of cardboard 1 or 2 blisters.

Pharmachologic effect

Mode of action - antidepressant.

Dosing and Administration

Inside, swallowing whole, not dividing, not chewing.

Before the start of therapy, hypokalemia should be eliminated.

The dosage regimen and the way of using the drug are set individually, taking into account the patient's condition. The goal of the treatment is to achieve the optimal effect when using the lowest possible doses of the drug and carefully increasing them. Special care should be taken with increasing doses in elderly patients and adolescents, who are generally more sensitive to the drug Anafranil® CP than patients in intermediate age groups.

Depression, obsessive-compulsive syndromes and phobias

The initial daily dose is 75 mg; prescribe the drug Anafranil® 25 mg 2-3 times a day, or the drug Anafranil® CP 75 mg once a day (preferably in the evening). Then, during the first week of treatment, the dose is gradually increased, for example by 25 mg every few days (depending on tolerability) to a daily dose of 100-150 mg. In severe cases, the daily dose can be increased to a maximum of 250 mg. After the improvement is achieved, the patient is transferred to a maintenance dose of 50-100 mg (Table 1 of the preparation Anafranil® CP or 2-4 tablets of the preparation Anafranil®).

Panic attacks, agoraphobia

At the beginning of treatment, prescribe the drug Anafranil® at a dose of 10 mg / day. Then, depending on the tolerability, the dose of Anafranil® is increased until the desired effect is achieved. The daily dose varies greatly and can range from 25 to 100 mg. If necessary, it is possible to increase the dose to 150 mg / day. It is recommended not to discontinue treatment for at least 6 months, slowly reducing during this time the maintenance dose.

Cataplexy accompanying narcolepsy

The daily dose is 25-75 mg.

Chronic Pain Syndromes

The dosage regimen is set individually. The daily dose varies considerably and can range from 10 to 150 mg. In this case, the concomitant use of analgesic drugs and the possibility of reducing the use of the latter should be considered.

Patients of advanced age. At the beginning of treatment, prescribe the drug Anafranil® at a dose of 10 mg / day. Then gradually, approximately for 10 days, the daily dose is raised to the optimal level, which is 30-50 mg.

Children and teens

Obsessive-compulsive syndromes

Begin the treatment with the appointment of the drug Anafranil®. The initial dose is 25 mg / day. During the first 2 weeks, the dose is gradually increased, taking into account tolerability, to a daily dose of either 100 mg or calculated at 3 mg / kg, whichever dose is less. Over the next few weeks, the dose is gradually increased to a daily dose of either 200 mg or calculated at 3 mg / kg, whichever is lower.

Nocturnal enuresis

The initial daily dose of the drug Anafranil® for children aged 5-8 years is 20-30 mg; for children aged 9-12 years - 25-50 mg; for children older than 12 years - 25-75 mg. The use of higher doses is indicated for those patients who have completely no clinical effect after 1 week of treatment. Usually the whole daily dose of the drug is prescribed in one session after dinner, but in cases when involuntary urination is noted in the early hours of the night, part of the dose of Anafranil® is prescribed earlier - at 16 hours. After achieving the desired effect, treatment should be continued for 1-3 month, gradually reducing the dose of the drug Anafranil®.

Storage conditions for Anafranil SR

At a temperature not exceeding 30 ° C.

Keep out of the reach of children.

Shelf life of Anafranil SR

5 years.

Do not use after the expiry date printed on the package.

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