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Instruction for use: Aminophyllin

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Dosage form: Solution for intravenous administration; Substance-powder; Suppositories rectal; Retard tablets

Active substance: Aminophyllinum


R03DA05 Aminophylline

Pharmacological group

Adenosinergic agents

The nosological classification (ICD-10)

I50 Heart failure: Exacerbation of chronic heart failure; Shortness of breath with acute heart failure; Acute heart failure; Acute heart failure; Heart failure on the background of intoxication; Heart failure on the background of infections; Acute Heart Failure; Chronic myocardial insufficiency; Cardiac dyspnea

I63 Cerebral infarction: ischemic Stroke; Ischemic brain disease; Ischemic stroke; Ischemic stroke and its consequences; Ischemic cerebral stroke; Ischemic cerebrovascular accident; Ischemic brain damage; Ischemic brain damage; ischemic conditions; Cerebral ischemia; Acute hypoxia brain; Acute cerebral ischemia; Acute ischemic cerebrovascular accident; Acute cerebral infarction; Acute ischemic stroke; Acute period of ischemic stroke; Focal cerebral ischemia; Ischemic stroke; recurrent stroke; The syndrome of Morgagni-Adams-Stokes; Chronic cerebral ischemia; cerebrovascular stroke; embolic stroke; Ischemic brain damage

J45 Asthma: Asthma of physical effort; Asthmatic conditions; Bronchial asthma; Bronchial asthma of light course; Bronchial asthma with difficulty in sputum discharge; Bronchial asthma of severe course; Bronchial asthma physical effort; Hypersecretory asthma; The hormone-dependent form of bronchial asthma; Curbing asthma attacks with bronchial asthma; Non-allergic bronchial asthma; Night Asthma; Exacerbation of bronchial asthma; Attack of bronchial asthma; Endogenous forms of asthma; Night attacks of asthma; Cough with bronchial asthma

J98.8.0 * Bronchospasm: Bronchospasm with bronchial asthma; Bronchospasm when exposed to an allergen; Bronchospastic reactions; Bronchospastic conditions; Bronchospastic syndrome; Diseases accompanied by bronchospastic syndrome; Reversible bronchospasm; Spasmodic cough

Composition and release form

1 ampoule with 10 ml solution for injection contains aminophylline 240 mg; In the box there are 10 ampoules.

Pharmachologic effect

Mode of action - bronchodilating, diuretic, spasmolytic, vasodilating.

Inhibits phosphodiesterase, increases the intracellular content of cAMP.


Strongly and rapidly expands the musculature of the bronchi. Excites vasomotor center, dilates blood vessels (mainly vessels of the brain, skin and kidneys), shows spasmolytic effect in relation to peripheral venous vessels and reduces venous pressure, increases renal blood flow, stimulates diuresis.

Indication of the drug Aminophyllin

Bronchial asthma, bronchitis, asthmatic state, stroke, chronic (congestive) circulatory insufficiency (in combination with diuretics and cardiac drugs).


Hypersensitivity, acute myocardial infarction, the first half of pregnancy.

Side effects

Nausea, vomiting, exacerbation of peptic ulcer of stomach and duodenum, dizziness, palpitation, insomnia, increased excitability, disorientation, hallucinations, heart rhythm disturbances, collapse, hypoglycemia.


Ephedrine and the agents containing it increase the risk of side effects. Reduces the effect of indirect anticoagulants. Propranolol weakens the effect on heart rate and bronchial tone. Pharmaceutically incompatible with glucose solutions.

Dosing and Administration

IV, IM. Adults, IV, slowly - 240 mg (1 ampoule - 10 ml) 1-2 times a day; Children, IV or in IM: up to 3 months - 30-60 mg, from 4 to 12 months - 60-90 mg, from 2 to 3 years - 90-120 mg, from 4 to 7 years - 120-240 Mg, from 8 to 18 years - 240-480 mg per day in 2-3 injections.

Storage conditions of the drug Aminophyllin

In the dark place.

Keep out of the reach of children.

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