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Phenylpiracetam (Carphedon, Phenotropil) capsules - instructions for use, analogs, reviews

10 Jul 2018

Phenotropil (Phenylpiracetam, Carphedon) is a new drug of a group of nootropics that improve brain blood supply and cognitive functions (thinking, memory, attention, etc.). In addition, Phenotropil has a psychostimulatory effect, improving endurance under high emotional stress, tension, mood swings and other similar conditions. Due to these properties, Phenotropil is used in the treatment of diseases of the Central nervous system, such as cerebral circulation failure, neuroses, asthenia, depression, apathy in schizophrenia, abstinence after drinking alcohol or drugs. In healthy people, Phenotropil is used to increase resistance to stress and to prevent fatigue in severe mental and physical stress.

phenylpiracetam

The composition, names and method of production

Currently, Phenotropil is only available in pill form with the active substance 50 mg or 100mg.

Pills are sold in packs of 10, 20 or pieces. To quickly refer to the different dosages of the drug in everyday speech are often used the terms "Phenotropil 100"or" Phenotropil 50". In these names, the numbers mean the dosage of tablets. In addition, the names "Phenotropil 30" or "Phenotropil 20" are sometimes used to refer to how many tablets are in the described package.

However, these names are used much less frequently compared to those where the name Phenotropil is added to the figure indicating the content of the active substance. Part of Phenotropil as the active component includes phenyl-oxo-pyrrolidinyl-acetamide a substance that briefly is called "Phenotropil". Actually, according to the short name of the active substance, the drug got its trade name. Tablets may contain phenyl-oxo-pyrrolidinyl-acetamide in two doses 50 mg or 100mg. As auxiliary substances Phenotropil contains the following components:

  • Potato starch;
  • Lactose;
  • calcium Stearate.

Phenotropil tablets are in the form of an elongated cylinder, flattened on both sides, and painted white or white with a yellowish or cream tint.

Therapeutic action and clinical effects of Phenylpiracetam

Phenotropil has the following clinical effects:

  • posed anti-amnesic effect of (the drug improves memory including at the expense of its consolidation and accelerate the speed of transmission of nerve impulses between the various structures of the brain);
  • Activates the integrative brain activity, i.e., improves memory and intelligence, enhances concentration, increases the activity of mental performance and the ability to tolerate high intellectual exertion;
  •  Improves ability to learn and assimilate new information and mastering new skills;
  • Increases resistance of the brain to oxygen deficiency (hypoxia) and toxic agents;
  • Anticonvulsant effect;
  •  Anxiolytic (calming) effects;
  • Improves your mood, to treat depression;
  • Normalizes and balances the processes of excitation and inhibition in the Central nervous system;
  • Enhances physical and mental performance;
  • Increases the number of different ideas, contributes to the emergence of non-standard vision of the situation and several solutions;
  • Increases pain threshold;
  • Improves vision (increase in sharpness, brightness, expansion of fields of vision).

The listed clinical effects of Phenotropil are provided by Its ability to accelerate metabolism and blood supply in brain tissues. In addition, the drug accelerates the oxidation-reduction processes in brain cells, which provide them with the necessary energy for active work. Improvement of mood and reduction of depressive component are achieved due to the ability of Phenotropil to increase the content of noradrenaline, dopamine and serotonin in the nerve fibers of the brain. These substances affect the speed of transmission of nerve impulses, regulate feelings of happiness and pleasure, and also maintain a good mood. The stimulating effect of Fenotropil (increased mental and physical performance) is combined with a calming effect. That is, a person on the background of taking the drug is able to work intensively and powerfully, but at the same time remain calm and not subject to anxiety, nervousness or fears. Resistance to the negative effects of oxygen deficiency, toxic substances, low temperatures, fatigue and immobility is given to brain cells due to the action of Carphedon adaptogenic. At the same time, Phenylpiracetam does not affect the respiratory and vasomotor centers of the medulla oblongata, so it does not change breathing, but reduces blood pressure. However, Phenotropil has a weak diuretic effect. When using the exchange rate Phenylpiracetam can provoke anorexia by suppressing appetite. A very important property of 1.3 dimethylamine is that it does not develop addiction and tolerance, and after discontinuation of the drug does not occur withdrawal syndrome. All the effects of Phenotropil develop after a single dose of the drug, which allows its use if necessary, and not necessarily long-term courses.

Phenylpiracetam experience, indications for use

Phenotropil is indicated for use for the treatment and prevention of pathological conditions of the Central nervous system: Rehabilitation after traumatic CNS injury (e.g. traumatic brain injury, meningitis, etc.); Chronic cerebrovascular insufficiency, accompanied by a deterioration of mental abilities and memory, as well as a decrease in motor activity; Asthenic syndrome, combined with cerebrovascular insufficiency; Neuroses; a Condition in which the person concerned about the lethargy, exhaustion, low activity, attention disorders and poor memory; The decline in learning ability; Depression asthenic, apathetic and dinamicheskogo Genesis; Shallow psycho-organic syndromes that manifest violation of intelligence and memory, as well as the phenomena of bulimia and apathy; a state of lethargic apathy, when schizophrenia; Convulsions of various origins; Alcohol withdrawal (alcohol withdrawal syndrome); Chronic alcohol and drug abuse (in the complex treatment for the relief of fatigue, elimination of depression and restore memory and mental abilities); In the complex treatment of arterial hypertension I II stages; Complex therapy of obesity, not associated with endocrine disorders; Prevention of brain hypoxia; increased resistance to stress; Correction of functional state in contact with various unusual or extreme conditions (for example, the need to work in an unusual climatic or time zone, etc.); prevention of fatigue and increase of mental and physical performance in cases where necessary; Normalization of biorhythm; Violation of the cycles of "sleep-wakefulness" with rapid movement of 4 or more time zones.

Phenotropil-instructions for use

Tablet Phenotropil should be swallowed whole, without chewing or grinding in any other way. The tablet should be washed down with enough water-at least half a glass. It is optimal to take Phenotropil immediately after eating. However, if this option is not possible for any reason, it is recommended to take the pill after a meal, not on an empty stomach. This recommendation is due to the fact that Phenylpiracetam reduces appetite up to anorexia.

Carphedon dosages are selected individually, based on the human condition and the desired therapeutic effect. The average single dose of Phenotropil is from 100 mg (1 tablet 100 mg) to 200 mg (2 tablets 100 mg), and the daily dose from 200 mg to 300 mg. the Maximum allowable daily dose of Phenotropil is 750 mg (7.5 tablets 100 mg or 15 tablets 50 mg). It is optimal to take the drug twice a day-morning and afternoon. It is not recommended to take the drug later than 15-00 hours, because there may be difficulties with falling asleep. However, if the daily dose is 100 mg or less, you can take it at a time in the morning. The duration of course therapy with Phenotropil is from 2 weeks to 3 months. If necessary, the course of treatment can be repeated at intervals of not less than one month. However, Fenotropil courses should be taken for the treatment of various conditions and diseases. And for the temporary improvement of performance and adaptation to unusual conditions it is enough to use Phenotropil for a short period of time from several days to two weeks. To improve performance and memory, as well as improve attention Phenylpiracetam should be taken on 100 200 mg (1 2 tablets) once a day for 2 weeks. You can also take Phenotropil 100 200 mg once a day for three days as a preparation for intensive physical training or powerful mental stress. When obesity Phenotropil in the complex therapy is recommended to take 100-200 mg 1 time a day for 1 2 months. If Phenotropil is taken against the background of psycho-emotional exhaustion, fatigue or chronic stress and insomnia, you should be prepared for the fact that after the first dose of the drug a person will need a long sleep. If a person works, it is recommended to start taking the drug on weekends to be able to sleep as much as necessary to the body.

Phenotropil should be used with caution in people suffering from liver and kidney diseases, severe hypertension or atherosclerosis. This means that during the entire course of treatment it is necessary to carefully monitor your own health and to fix the slightest changes, which should be reported to the doctor. You should also regularly take tests that reflect the state of the kidneys, liver and the number of lipid fractions in the blood.

In addition, Phenotropil should be taken with caution to people who have previously suffered panic attacks, anxiety, psychosis or periods of psychomotor agitation, because the drug can lead to a new manifestation of these diseases. Also, there may be an exacerbation of anxiety, the appearance of panic, hallucinations and delirium in people who have allergic reactions to the compounds of the pyrrolidone group (for example, Piracetam, Fezam, etc.).

When the first signs of mental instability against the background of the use of Fenotropil, it is necessary to immediately cancel the drug and consult a doctor as soon as possible. If in the first three days of receiving Phenlpiracetam in humans there were side effects (feeling of heat, redness of the skin, increased pressure or excessive excitation), it is recommended to reduce the dosage by half and then gradually, within 2 to 7 days to bring it to the prescribed.

fenotropil

Interaction with other drugs

Phenotropil enhances the effects of other psychostimulatory drugs and substances, as well as antidepressants and nootropics. In addition, Phenotropil reduces the effect of neuroleptics and weaken the hypnotic effect of ethyl alcohol and hexenal.

The overdose of Phenotropil for the entire period of its clinical use has not been recorded even once. The drug is normally carried in dosages of up to 800 mg (8 tablets of 100 mg) per day.

Phenotropil for children

Phenotropil is a drug that is not recommended for children, because there is no adequate and reliable studies proving its safety for them. However, in clinical practice, it is allowed to use the drug for severe diseases, when the benefit of it will undoubtedly exceed all possible risks and side effects. Unfortunately, at the present time in the countries of the former Soviet Union has developed a very bad practice of overdiagnosis of neurological diseases and psychiatric disorders in children of early age. This means that in young children identify diseases that they do not actually suffer.

The most common such diseases are perinatal encephalopathy, intracranial pressure, hydrocephalic syndrome, as well as "deviations" in the brain structure revealed during sonography, EEG or Echocardium, such as, for example, an increase in the ventricles by 1 3 mm more than the norm, thickening of the septum, etc. Parents agree with the doctors, because it seems to them that the child does not sleep well, does not cry, takes off the blanket, bends, wakes up and does not correspond to the prevailing ideas in their head.

However, this is hyperdiagnosis, since there are no objective data on the presence of the disease, and there are only indicators of outdated studies and subjective impressions of parents and doctors, which without clinical symptoms are a reflection of the normal option. After all, the child is not made according to the patterns, he is alive, he has individual properties that may differ from the standards available in the clinic, very far from perfect. Therefore, parents should remember that only the presence of long-existing clinical symptoms, which does not pass within a few weeks, is a cause for concern. In all other cases, if the child occasionally sleeps poorly, not as you want to eat, has a " bad " EEG, sonography or Echocardiography, but gaining weight and develops according to age, there is no reason to worry.

Returning to Fenotropil, it should be said that in the countries of the former USSR, the drug is administered to children for treatment of various "diseases" identified in the course of overdiagnosis. Thus, the drug is often used to normalize sleep, eliminate "capriciousness" and excitability in the child, as well as to accelerate its development. Strictly speaking, this use of Phenotropil can not be called correct and reasonable, so all the recommendations remain on the conscience of a particular doctor and parent.

Phenotropil is also recommended to take children of school age to eliminate the following conditions:

  • Frequent stress situations;
  • Emotional burnout;
  • Depression;
  •  Low ability to learn;
  • mental Retardation;
  • Paralysis and paresis.

In these situations, Phenotropil can really have a positive effect, normalizing the child's condition. However, the drug should be used carefully, tracking the appearance of side effects or deterioration of the child. If any, you should stop taking Fenotropil and see a doctor. Children can take Phenylpiracetam 50 mg 2 times a day for 2 to 4 weeks. Longer courses of admission are not recommended, because the child may form a psychological dependence on pills.

Phenylpiracetam and alcohol

Phenotropil reduces the effect of alcohol on the brain, so against the background of taking the drug a person gets drunk much less than usual, the head remains sober and clear. In addition, in the morning after a stormy libation, symptoms of "hangover" or completely absent, or mild. However, this does not mean that against the background of receiving Phenotropil, you can drink alcoholic beverages in any amount. The negative effect of the combination of Phenotropil and alcohol is manifested after the removal of all the products of the decay of ethyl alcohol, when the process of the death of brain neurons in large quantities is started. This is due to the fact that Phenotropil activates metabolism in brain cells. Against the background of intensive metabolism of the cells absorb toxic metabolites of alcohol, poisoned and after a while literally die EN masse.

To visualize the effect on the brain cells produces a combination of Phenotropil + alcohol, it is necessary in the imagination to draw a picture of being in a room where a toxic substance is sprayed, for example, carbon monoxide. To reduce the impact of a toxic substance, a person will try to breathe as little as possible and shallow. But if you breathe deeply and intensely at this moment, the poisoning will be very strong, possibly fatal. In this analogy, the action of Phenotropil can be compared with intensive breathing, due to which there is a large amount of harmful substance absorption, and alcohol is a toxic compound that destroys brain cells.

That is, under the influence of Phenotropil brain cells receive more than usual amount of toxic alcohol metabolites, which trigger the process of their intensive destruction. Therefore, the effects of alcohol in combination with Phenotropil on brain cells are even more detrimental compared to only ethyl alcohol. In addition, in the initial depressed state of the Central nervous system, which just causes alcohol, Phenotropil does not have a psychostimulatory effect, but, on the contrary, overwhelming. That is, increases the oppression of the CNS.

How to take Phenotropil for weight loss

Fenotropil is used in the treatment of obesity, not associated with hormonal disorders, that is, caused by constitutional features or overeating. This means that theoretically Phenotropil can be used for weight loss. However, before making such a decision, it is necessary to know what is causing its effect. So, Phenylpiracetam really helps to reduce weight due to the fact that it has anorexigenic activity, that is, simply completely eliminates appetite and hunger.

Thanks to this, a person does not want to eat, the amount of calories consumed is reduced, and the excess weight is lost. That is, Phenotropil does not break down body fat, does not bind nutrients received by the body, but simply reduces appetite, which makes it a relatively safe drug for weight loss.

After all, as a result of its action from the gastrointestinal tract, all the nutrients that have entered the body are normally absorbed, and the digestion process is not disturbed, proceeding completely normally. This means that Phenotropil will be very effective in combination with a diet that will directly help reduce weight, and the drug, in turn, will help to comply with it without any problems and inconveniences associated with hunger. However, if a person does not follow any diet or will continue to eat as much as before the use of Phenotropil, he will not lose weight.

Remember that the drug only eliminates hunger, which allows you to eat less and, accordingly, to lose weight, but the Fenotropil itself directly on the fat tissue does not have any action. For weight loss Phenotropil is recommended to take 50 mg twice a day for the required period of time. People who are obese, Phenotropil under the supervision of a doctor can take up to 23 months. If a person takes Carphedon for weight loss on their own, without medical supervision, it can be done for a maximum of one month. The second course can be held after a break of at least three months.

Phenotropil-side effects

Phenotropil can provoke the development of the following side effects:

  • Insomnia (usually occurs when taking pills after 15-00 hours);
  • Hyperstimulation (excitement, energy, the desire to do everything at once, etc.);
  • Psychomotor agitation;
  • increased blood pressure;
  • Redness of the skin;
  • Feeling of heat on the skin.

All of these side effects, except insomnia, develop and disturb a person in the first three days from the beginning of taking Phenotropil, and then disappear. Thus, the body reacts to the introduction of the drug, but after addiction, which lasts from one to three days, the condition is normalized and side effects disappear.

Phenotropil analogues

In the pharmaceutical market there is only one synonym Phenotropil is Carphedon drug containing the same active substance. However, there is a wide range of Phenotropil analogues, that is, drugs that have similar therapeutic effects, but contain a different active substance. Analogues of Phenotropil are the following drugs:

1. Acephen tablets; 2. Bradenton concentrate; 3. Vero-Vinpocetine tablets; 4. Vinpotropil capsules and solution; 5. Vinpocetine tablets and concentrate; 6. Vinpocetine Forte tablets; 7. Vinceti tablets; 8. Glycine and Glycine Forte tablets; 9. Gopantsam pills; 10. Demanol solution; 11. Idebenon capsules and tablets; 12. Cavinton tablets and concentrate; 13. Cavinton Forte; 14. Calcium gopantenat tablets; 15. Carnitin capsules; 16. Kogitum solution; 17. Combitrain capsules; 18. Karsavin and Karsavin Forte tablets; 19. Cortexin lyophilizate and dry extract; 20. Lucetam tablets and solution; 21. Memotropil tablets; 22. Minisem drops; 23. Neuromet capsules; 24. Noben capsules; 25. Nooka capsules; 26. Nooclerin solution; 27. Noopept tablets; 28. Nootropil capsules, tablets and solution; 29. Omaron tablets; 30. Pantogam syrup and tablets; 31. Pantocalcin tablets; 32. Picamilon tablets and solution; 33. Spiractin capsules; 34. Piracetam granules, capsules and solution; 35. Piriditol tablets; 36. Celectol tablets; 37. Thiocetam tablets and solution; 38. Fezam capsules; 39. Celesta capsules; 40. Cellex solution; 41. Ceraxon solution; 42. Cerebrolysate solution; 43. Cerebrolysin solution; 44. Encephabol tablets and suspension; 45. Epithalamin powder; 46. Isotropic solution.

Phenylpiracetam Reviews

About 70% of the reviews of Phenotropil are positive and 30% are negative. Most often people used the drug to improve mental and physical performance, when it was necessary to perform a large amount of work for a limited period of time or to remember a lot of new information. In other words, the help of Phenotropil is most often used by people who need to improve the efficiency of their work for any reason, to get an excellent concentration of attention, memory, intelligence and high intensity of intellectual activity.

The vast majority of reviews of Fenotropil when used for the purpose of" brain activation " are positive, because the effect was pronounced, clearly visible, and people had time to do everything they wanted and planned. It is worth noting that Phenotropil has its effect after a single application, to achieve a pronounced clinical effect it is not necessary to take for a long course. This quality of the drug is a very important advantage for many people who need a single pronounced effect and do not need to take nootropics-psychostimulants courses, because in the normal rhythm of life they do not need them. A few less common feedback about the use of Phenylpiracetam in the extreme fatigue, loss of strength, irritability, weakening of memory and attention, samotnosci, etc. In such situations, the feedback on Fenotropil in 2/3 cases positive, and 1/3 negative. Positive due to the fact that after the course of application of Phenotropil, the state of people was normalized. Negative reviews of Phenotropil are due to a number of factors the presence of hard to-tolerate side effects, addiction when taken at a dose of 2-3 tablets per day, insomnia, anxiety, excessive sweating. People who took the drug, noted that the clinical effect is there, but the" payback " for it comes after, and it is very unpleasant and hard to tolerate. Therefore, they consider Phenotropil to be a potent drug that can be taken only by a doctor's prescription if there are indications, and it is not suitable for activating the brain in a healthy person.

Doctors Reviews of Phenylpiracetam

Doctors ' reviews of Phenotropil are usually positive, but with a mandatory alarming component. The positive opinion of doctors is based on the high clinical efficacy of the drug, which really activates the brain, improves memory, reaction speed, concentration and, in principle, improves intellectual function. That is, if you need to get the effect of an active, well and quickly working brain, Phenotropil is an excellent tool that works, both with a single and with course use. However, together with the indication of an excellent clinical effect in the reviews, doctors always insert a disturbing potential user of Phenotropil aspect, which usually consists in describing the condition that occurs after the termination of the "miracle pill".

This condition is very unpleasant, painful and poorly tolerated, because a person feels depressed, inhibited and clearly bad work of the brain. Figuratively we can say that after a great intelligence on the background of Phenylpiracetam comes complete stupidity, when not just no clarity and clarity of thought, and it is impossible to remember and pick up the usual words to describe everyday situations. This is due to the fact that Phenotropil gives energy and increased mental activity from the hidden reserves of the body, which then have to be restored. And after the action of the drug ends, there is a natural fatigue, multiplied by the depletion of the body's reserves. Moreover, the period of recovery, inhibited state and dullness will last the longer the longer was the reception of Phenotropil.

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