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Pantocalcin (Acidum hopantenicum, Acid hopantenic) – nootropic.
The spectrum of action is associated with the presence of GABA structure. The mechanism of action is due to a direct effect of the drug on Pantocalcin GABA B receptor-channel complex. It has neurometabolic, neuroprotective and neurotrophic properties. Increases resistance to cerebral hypoxia and exposure to toxic substances, stimulate anabolic processes in neurons. It has anticonvulsant effect, reduces the excitability of the motor while the ordering behavior. It improves mental and physical performance. Promotes normalization of GABA in chronic alcohol intoxication and the subsequent lifting of ethanol. Exhibits analgesic effect. Is able to inhibit the acetylation reaction involved in the mechanisms of inactivation of novocaine and sulfonamides, and thus a prolonging action of the latter. It causes inhibition of pathologically elevated cystic and reflex detrusor tone.
Take 15-30 minutes after eating.
Single dose for adults is 0.5-1 g, for children - 0.25-0.5 grams daily - 1.5-3 g (for adults), 0,75-3 g (for children). Duration of treatment - from 1 to 4 months, in some cases - up to 6 months. After 3-6 months may conduct re-treatment.
Children. Mental failure - 0.5 g 4-6 times a day, daily for 3 months. Delayed speech development - 0.5 g 3-4 times a day for 2-3 months.
Neuroleptic syndrome (corrector as side effects of neuroleptics). Adults - 0.5-1 g 3 times per day; children - 0.25-0.5 g 3-4 times a day. Duration of treatment - 1-3 months.
Epilepsy. Children - at 0.25-0.5 g 3-4 times a day; adults - 0.5-1 g 3-4 times daily for a long time (up to 6 months).
Hyperkinesia (tics). Children - 0,25-0,5 g 3-6 times daily for 1-4 months; Adults - 1.5-3 g per day every day for 1-5 months.
Disorders of urination. Adults - 0.5-1 g 2-3 times a day (daily dose - 2.3 g); children - by 0.25-0.5 g (daily dose - 25-50 mg / kg). Duration of treatment - from 2 weeks to 3 months (depending on the severity of disorders and therapeutic effect).
Consequences neuroinfections and traumatic brain injury. 0.25 g of 3-4 times a day.
To restore the efficiency at high loads and asthenic sostoyaniyah.0,25 g 3 times a day.
This dosage form is not recommended for children under 3 years.
Prolonging effect of barbiturates; It enhances the effects of drugs that stimulate the central nervous system, anticonvulsant drugs, the effect of local anesthetics (procaine). Prevents side effects of these drugs: phenobarbital, carbamazepine, antipsychotics (neuroleptics).
Action hopantenic acid amplified in combination with glycine, ksidifonom.
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