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Sermion (Nicergolinum, Nicergoline) - drug improving cerebral and peripheral circulation, with an alpha-adrenoceptor blocking and metabolism activating action.
Decreases vascular resistance, increases arterial blood flow and oxygen consumption and glucose brain tissue. It lowers pulmonary vascular resistance. It reduces platelet aggregation and improves hemorheological indexes.
It increases blood flow in the vessels of the upper and lower extremities, especially in case of violation of blood flow, caused functional arteriopathy. Clinical trials have shown high efficiency of Sermion at blood flow in the vessels of the upper and lower extremities and cerebrovascular disorders failure.
Reception Sermion at therapeutic doses, usually has no effect on blood pressure. In patients with hypertension drug may cause a gradual reduction in blood pressure.
Nicergoline - ergoline derivative improves hemodynamic and metabolic processes in the brain, decreases platelet aggregation and improve hemorheological parameters of blood, increases blood flow in the upper and lower extremities. Nicergoline exhibits α1-adrenoceptor blocking action, leading to an improvement in blood flow, and has a direct effect on cerebral neurotransmitter systems - adrenergic, dopaminergic and cholinergic. Against the background of the drug increased the activity of adrenergic, dopaminergic and cholinergic cerebral systems that helps to optimize cognitive processes. As a result, long-term therapy nicergoline seen sustained improvements in cognitive function and decrease the severity of behavioral disturbances associated with dementia.
Effects on ability to drive vehicles and other machines that require high concentration of attention
Sermion improves concentration. Effect on ability to drive vehicles and use machines have never been studied. Nevertheless, in view of the disease, about which prescribers are advised to be cautious when driving or operating machinery.
Inside the drug prescribed to 5.10 mg three times / day with the same intervals between doses for a long period of time. To improve absorption of the drug should be taken between meals.
In some cases, it is advisable to start treatment with parenteral administration (Sermion por.liof.d / in. 4 mg vial. 4 ml [with p-lem] y. 4 Pfizer), followed by the transition to the ingestion during the period of maintenance therapy.
For the convenience of dosing the drug can be used Sermion tabl.po 5 mg pack. 30 Pfizer.
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