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Instructions

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Instruction for use: Anatoxinum diphtherico-tetanicum purificatum adsorptum cum quantitate minore antigenorum fluidum

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Dosage form: Suspension for intramuscular administration; Suspension for intramuscular and subcutaneous administration

Active substance: Anatoxinum diphterico-tetanicum

ATX

J06AA Immune Serums

Pharmacological group:

Vaccines, serums, phages and toxoids

The nosological classification (ICD-10)

Z27.8 The need for immunization against other combinations of infectious diseases

Composition and release form

One vaccine dose (0.5 ml) of the vaccine contains 5 flocculating units (LF) of the diphtheria and 5 antitoxin-binding units (EC) of tetanus toxoid. Sorbent - aluminum hydroxide - 0,25-0,55 mg / ml. Preservative-merthiolate is 0.05 mg / ml. Ampoules of 1 ml (two inoculations), in the package 10 pcs.

Characteristic

ADS-M-anatoxin with a reduced antigen content consists of a mixture of purified diphtheria-tetanus toxoid adsorbed on aluminum hydroxide. The preparation is a suspension of white or slightly yellowish color, separated when standing on a clear liquid part and a loose sediment, completely shattered by shaking.

Pharmachologic effect

Mode of action - Immunostimulating.

Forms immunity against diphtheria and tetanus.

Indication of the drug Anatoxinum diphtherico-tetanicum purificatum adsorptum cum quantitate minore antigenorum fluidum

Diphtheria, tetanus (prophylaxis).

Contraindications

Acute infectious diseases (no earlier than 2-4 weeks after recovery), exacerbation of chronic diseases, pregnancy.

Side effects

Rarely: fever, weakness, tenderness in the place of inoculation, hyperemia, puffiness, allergic reactions and exacerbation of allergic diseases.

Dosing and Administration

IM, in the upper outer quadrant of the buttocks, antero-anterior part of the thigh or sciatica in the scapular region in a single dose of 0.5 ml. Before vaccination, the ampoule must be shaken thoroughly until a homogeneous suspension is obtained. The vaccination course consists of two vaccinations with an interval of 30-45 days. The first revaccination is carried out once 6-9 months after the finished vaccination, the second booster vaccination with an interval of 5 years.

Precaution measures

After the introduction, it is necessary to observe the vaccinated for 30 minutes (the possibility of developing allergic reactions). The preparation is not suitable for use in ampoules with broken integrity and marking, with a change in physical properties, with expired shelf life, improper storage.

Storage conditions of the drug Anatoxinum diphtherico-tetanicum purificatum adsorptum cum quantitate minore antigenorum fluidum

In the dark place at a temperature of 4-8 ° C.

Keep out of the reach of children.

Shelf life of the drug Anatoxinum diphtherico-tetanicum purificatum adsorptum cum quantitate minore antigenorum fluidum

3 years.

Do not use after the expiry date printed on the package.

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