Instruction for use: Vero-Danazol
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ATX Code G03XA01 Danazol
Active substance: Danazol
Pharmacological group
Hormone Hypothalamus, Hypophyse, Gonadotropin und deren Antagonisten
Nosological classification (ICD-10)
E30.1 Premature puberty
Premature puberty, Premature sexual development, Premature puberty in girls, Early puberty, Primary premature puberty
N60.1 Diffuse cystic mastopathy
Benign cystic change in mammary glands, Cystic fibrosis mastopathy, Fibrous-cystic mastopathy, Pre-cancerous condition of mammary glands, Benign mammary gland disease, Benign breast tumor
N62 Hypertrophy of the breast (breast) gland
Gynecomastia, Hypertrophy of the mammary glands, Macromastia
N80 Endometriosis
Endometrioid endometriosis
N92 Abundant, frequent and irregular menstruation
Metromenorragii, Menorrhagia, Menorrhagia primary, Polymenorea, Idiopathic menorrhagia, Menorrhagia, Functional metronormorragia, Primary menorrhagia
N94.3 Premenstrual tension syndrome
Pronounced premenstrual syndrome, Menstrual psychosomatic disorder, Menstrual syndrome, Premenstrual tension, Premenstrual status, Premenstrual period, Premenstrual syndrome, Menstruation syndrome
N97 Female infertility
Female infertility in anovulation, Hyperprolactinemic infertility, Hyperprolactinaemia with infertility, Endocrine infertility, Infertility due to hypothalamic-pituitary dysfunction, Infertility infertility, Infertility, Infertility on the background of hyperprolactinaemia, Functional infertility, Marriage is infertile, Infertility of ovarian genesis, Stimulation of the growth of a single follicle
Composition
1 capsule contains danazol 100 or 200 mg; In a contour acheikova packing 10 pcs., In a cardboard bundle 1 or 3 packings.
pharmachologic effect
The pharmacological action is antigonadotropic.
Suppresses the production of pituitary gonadotropic hormones (LH and FSH), inhibits ovarian activity, inhibits ovulation, causes atrophy of the endometrium.
Indication
Endometriosis and the resulting infertility, mastopathy, primary menorrhagia, premature puberty in girls, macromastia, gynecomastia, premenstrual syndrome, hereditary angioedema.
Contraindications
Hypersensitivity.
Side effects
From the nervous system and sensory organs: increased intracranial pressure, dizziness, headache, agitation, nervousness, convulsions.
On the part of the digestive system: dyspeptic phenomena, nausea, a violation of the liver, cholestatic jaundice.
Other: alopecia, fluid retention in the body, weight gain, hot flashes, reduction in breast size, seborrhea, acne, hirsutism; backache.
Dosing and Administration
Inside, adults - 200-800 mg 2-4 times a day, the course - 6 months; Children - from 100 to 400 mg / day.
Precautionary measures
Before starting therapy in patients with amenorrhea, pregnancy should be excluded (if pregnancy occurs during treatment, it is immediately stopped). With caution appoint for violations of the heart, liver, kidney, migraine, epilepsy, diabetes.
storage conditions
In a dry place, at a temperature of no higher than 25 ° C.
Keep out of the reach of children.
Shelf life
3 years.
Do not use after the expiry date printed on the package.