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Instructions

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Instruction for use: Vaccinum staphylococcum therapeuticum fluidum

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Dosage form: Solution for subcutaneous administration

Active substance: Vaccine for the treatment of staphylococcal infections

ATX

J07AC Anthrax vaccines

Pharmacological group:

Vaccines, serums, phages and toxoids

The nosological classification (ICD-10)

L02 Abscess of skin, furuncle and carbuncle: Furuncle of external auditory canal; Furuncle of the auricle; Furuncles; Abscess; Abscess of skin; Carbuncle; Carbuncle skin; Furuncle; Skin furuncle; Furunculosis Chronic recurrent furunculosis

L08.9 Local infection of skin and subcutaneous tissue, unspecified: Soft tissue abscess; Bacterial or fungal infection of the skin; Bacterial skin infections; Bacterial infections of soft tissues; Bacterial skin infections; Bacterial skin lesions; Viral infection of the skin; Viral skin infections; Inflammation of cellulose; Inflammation of the skin at the injection site; Inflammatory skin diseases; Pustular skin diseases; Purulent-inflammatory disease of skin and soft tissues; Purulent-inflammatory skin diseases; Purulent-inflammatory diseases of the skin and its appendages; Purulent-inflammatory diseases of soft tissues; Purulent skin infections; Purulent infections of soft tissues; Skin Infections; Infections of the skin and skin structures; Infectious lesions of the skin; Infectious diseases of the skin; Skin Infection; Infection of the skin and its appendages; Infection of the skin and subcutaneous structures; Infection of the skin and mucous membranes; Infection of the skin; Dermal bacterial infections; Uncomplicated skin infections; Uncomplicated soft tissue infections; Surface erosion of the skin with secondary infection; Umbilical infection; Mixed skin infections; Specific infectious processes in the skin; Superinfection of the skin; Necrotizing subcutaneous infections

Composition and release form

Solution for subcutaneous injection 1 amp.

Complex of soluble thermostable antigens extracted from staphylococcus microbial cells by aqueous phenolic extraction

In ampoules of neutral glass of 1 ml, complete with a knife ampoule; In a pack of cardboard 10 ampoules.

Characteristic

Colorless transparent liquid with a specific odor.

Pharmachologic effect

Mode of action - Antimicrobial.

Pharmacodynamics

The introduction of the drug in accordance with the approved scheme causes in vaccines the formation of a specific antimicrobial anti-staphylococcal immunity.

Indications Vaccinum staphylococcum therapeuticum fluidum

Treatment of pustular skin diseases of staphylococcal etiology: furuncles, carbuncles, staphyloderma.

Contraindications

Acute infectious (non-staphylococcal etiology) and non-infectious diseases, including the period of convalescence, chronic diseases in the stage of exacerbation or decompensation;

Liver and kidney disease.

Treatment with staphylococcal vaccine is carried out not earlier than a month after recovery (remission).

Additional contraindications for children aged 6 months to 6 years:

Allergic diseases - bronchial asthma, common eczema and neurodermatitis, recurrent asthmatic bronchitis, Quincke's edema;

CNS disease;

Rickets of II and III degree;

Grade II and III hypotrophy;

Disease of the endocrine system.

In case of prematurity (body weight at birth <2.5 kg), treatment is performed provided that the child reaches normal age indices. In contact with infectious patients in the family, children's institution, etc. The drug is administered after the end of the quarantine.

Side effects

With the correct administration of the drug, taking into account contraindications, complications after the introduction of the vaccine is not observed.

Dosing and Administration

SC, in the area of the shoulder or in the subscapular region.

The course of treatment for adults and children from 7 years of age consists of a single daily injection according to the following scheme: Day 1 - 0.2 ml, 2nd - 0.3 ml, 3rd - 0.4 ml, 4th - 0.5 ml, the 5th - 0.6 ml, the 6th - 0.7 ml, the 7th - 0.8 ml, the 8th - 0.9 ml, the 9th - 1 ml.

For children from 6 months to 7 years, the dose for the first injection is 0.1 ml. If there is no reaction, the drug is administered daily according to the scheme, successively increasing each dose by 0.1 ml (0.2 ml for the second injection, 0.3 ml for the third injection, etc.). Each subsequent dose of the drug is administered at a distance of 20-30 mm from the site of previous injections or into the opposite arm.

With common skin lesions that occur with relapses, it is advisable to conduct a repeated course of treatment according to the same schedule 10-15 days later.

Precautionary measures

Reaction to administration. At the injection site, skin hyperemia and minor soreness may develop. In some patients, the administration of the drug may be accompanied by an increase in temperature of 0.5-1 ° C. After the first 2 injections in inflammatory foci soreness may increase. When developing a local or general reaction, the subsequent administration of the vaccine is carried out after the reaction disappears in the same dose as the previous one. In the case of a pronounced reaction to the administration of the vaccine (a fever of 38 ° C or higher, a significant pain in the inflammatory foci, an infiltration at the injection site of more than 20 mm in diameter), at the discretion of the attending physician, the interval between injections may be extended to 2-3 days, Or dose reduction with repeated injections.

Special instructions

The preparation is not suitable for use in ampoules with broken integrity, marking, changing physical properties (presence of opalescence, sediment), expired shelf life, improper storage. Opening of the ampoule with the vaccine and the vaccination procedure are carried out with strict adherence to the rules of aseptic and antiseptic. The vaccine in the opened ampoule should be used immediately.

Storage conditions of the drug Vaccinum staphylococcum therapeuticum fluidum

In a dry place, at a temperature of 2-10 ° C.

Keep out of the reach of children.

Shelf life of the drug Vaccinum staphylococcum therapeuticum fluidum

2 years.

Do not use after the expiry date printed on the package.

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