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Instructions

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Instruction for use: Vaccinum rabiei culturalt concentratum purificatum inactivatum siccum

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Dosage form: Lyophilizate for the preparation of a solution for intravenous and intramuscular administration; Lyophilizate for the preparation of a solution for intramuscular administration

Active substance:

Vaccine for prophylaxis of rabies (Vaccinum ad prophylaxim rabiei)

ATC

J07BG01 Inactivated whole rabies virus

Pharmacological group

Vaccines, serums, phages and toxoids

Nosological classification (ICD-10)

A82 Rabies:Rabies; Suspicion for rabies; Hydrophobia (hydrophobia)

Composition and form of release

Inactivated purified concentrated vaccine (culture of a production strain of rabies virus Vnukovo-32, grown on a primary culture of kidneys of a Syrian hamster), immunogenic activity of at least 2.5 IU / ml (1 dose). Stabilizers: gelatase - at a final concentration of up to 1%, sucrose at a final concentration of up to 7.5% and albumin at a final concentration of up to 0.1%. Lyophilizate in the form of a porous tablet in 1 ml ampoules complete with a solvent (distilled water) in 1 ml ampoules; In the package 5 sets.

pharmachologic effect

Pharmacological action - immunostimulating.

Forms immunity to the rabies virus.

Indication of the drug Vaccinum rabiei culturalt concentratum purificatum inactivatum siccum

Rabies (preventive and preventive immunization).

Contraindications

For treatment and prophylactic immunization, conducted according to vital indications, there are no contraindications. For preventive immunization: hypersensitivity, acute infectious and general diseases, congestive heart failure, chronic kidney and endocrine system diseases, collagenoses, bronchial asthma, pregnancy, lactation.

Side effects

Edema at the injection site, redness, itching, an increase in regional lymph nodes, malaise, headache, nausea, a slight increase in temperature.

Dosing and Administration

IM, the deltoid muscle of adults and children over 5 years. Children under 5 years of age are injected into the thigh muscles (upper part of anterolateral surface). The contents of the ampoule with the vaccine are dissolved in 1 ml of distilled water, the dissolved vaccine cannot be stored. Dosage and immunization schedule depends on the indications.

Precautionary measures

After the introduction, it is necessary to observe the vaccinated for 30 minutes (the possibility of developing allergic reactions). The preparation is not suitable for use in ampoules with broken integrity and marking, with changing physical properties (turbidity, intense staining, presence of non-breaking flakes), expired shelf life, improper storage.

Storage conditions of the drug Vaccinum rabiei culturalt concentratum purificatum inactivatum siccum

In a dry, the dark place at a temperature of 2-8 ° C.

Keep out of the reach of children.

Shelf life of the drug Vaccinum rabiei culturalt concentratum purificatum inactivatum siccum

17 months.

Do not use after the expiry date printed on the package.

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