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Instructions

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Instruction for use: Typhim Vi

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Dosage form: Solution for injection

Active substance: Vaccinum ad prophylaxim typhi abdominalis

ATX

J07AP03 Typhoid bacteria purified polysaccharide antigen

Pharmacological group:

Immunomodulating agent [Vaccines, serums, phages and toxoids]

The nosological classification (ICD-10)

A01.0 Typhoid: Typhoid of the abdominal; Paratyphoid; Typhus; Paratyphoid fever

Composition and release form

Solution for injection with 1 dose of polysaccharide vaccine for the prevention of typhoid contains 0.025 mg of purified capsular Vi-polysaccharide Salmonella typhi 0.025 mg, phenol (preservative) not more than 1.25 mg, buffer solution (from sodium chloride, sodium disodium hydrogen phosphate, sodium hydrophosphate dvuhvodnogo, water For injections) to 0.5 ml; In syringes of 0.5 ml (1 dose) or in bottles of 20 doses (10 ml), in a carton 1 syringe or 10 bottles.

Characteristic

Polysaccharide vaccine for the prevention of typhoid fever.

Pharmachologic effect

Mode action - immunomodulating.

Forms active specific immunity to the Salmonella typhi bacteria.

Pharmacodynamics

Specific immunity to the causative agent of typhoid fever develops 2-3 weeks after a single injection (SCI or IM) of the vaccine and persists for at least 3 years.

Indication of the drug Typhim Vi

Prevention of typhoid fever.

Contraindications

Hypersensitivity to vaccine components (history); Elevated body temperature, infectious disease (it is recommended to postpone), children's age (under 5 years)

Application of pregnancy and breastfeeding

Contraindicated in pregnancy; If necessary, a consultation with a specialist doctor of the appropriate profile is recommended.

Side effects

Often, within 24 hours - a slight soreness at the injection site; Rarely - redness, condensation at the injection site; It is possible (in 1-5% of cases) - an unbearable increase in body temperature.

Interaction

Not installed.

Dosing and Administration

SC or IM, single injection.

Precaution measures

Children under 2 years of age are not recommended for vaccination, from 2 to 5 years - only after consulting a specialist.

Storage conditions of the drug Typhim Vi

At a temperature of 2-8 ° C (do not freeze).

Keep out of the reach of children.

Shelf life of the drug Typhim Vi

17 months.

Do not use after the expiry date printed on the package.

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