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Cortexin - complex water-soluble polypeptide fractions with a molecular weight less than 10,000 Daltons.
Cortexin - antioxidant, nootropic, neuroprotective, tissue-specific
The drug improving cerebral metabolism. Cortexin lyophilisate is obtained by extracting the acetic acid from the cerebral cortex of cattle and pigs, containing low-molecular active neuropeptides, a molecular weight of less than 10,000 daltons, sufficient to penetrate the BBB.
Cortexin has tissue-specific multi-functional effect on the brain, which manifests itself in the metabolic regulation, neuroprotection, functional neuromodulation, neurotrophic activity.
Cortexin increases the efficiency of energy metabolism of the brain cells, improves intracellular protein synthesis.
Cortexin regulates lipid peroxidation in brain cells, reduces the formation of free radicals, blocks the processes of free radical oxidation. Preparation eliminates imbalance inhibitory and excitatory amino acids, has a moderate GABA-ergic activity.
The drug has a positive effect on cognitive impairment, improves concentration, short-term memory, learning ability, accelerates the recovery of brain function after stress effects, regulates the level of serotonin and dopamine. It stimulates the process of mental activity, without causing excess activating influence, restores bioelectric activity of the brain.
Cortexin stimulates reparative processes in the brain.
Cortexin adjusts the ratio of amino acids, and inhibition and excitation processes in the brain; he restores bioelectric activity of the brain. The maximal effect of the drug is manifested 2-3 weeks after treatment.
Individual intolerance to the drug.
Currently, the cases of overdose have been reported.
V / m. The contents of the vial prior to injection were dissolved in 1.2 ml of 0.5% solution of procaine (novocaine), water for injection or 0.9% sodium chloride solution by guiding the needle to the wall of the vial to avoid foaming, and is administered once daily: adult dose of 10 mg for 10 days; children with body weight 20 kg - 0.5 mg / kg body weight over 20 kg - 10 mg for 10 days.
If necessary, a second course of 3-6 months.
At the hemispheric ischemic stroke in the acute and early recovery periods adult dose of 10 mg 2 times a day (morning and afternoon) for 10 days, with a repeated course in 10 days.
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