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Instruction for use: Theostat

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Dosage form: Tablets of prolonged action divided

Active substance: Theophyllinum


R03DA04 Theophylline

Pharmacological group

Adenosinergic agents

The nosological classification (ICD-10)

J45 Asthma: Asthma of physical effort; Asthmatic conditions; Bronchial asthma; Bronchial asthma of light course; Bronchial asthma with difficulty in sputum discharge; Bronchial asthma of severe course; Bronchial asthma physical effort; Hypersecretory asthma; The hormone-dependent form of bronchial asthma; Curbing asthma attacks with bronchial asthma; Non-allergic bronchial asthma; Night Asthma; Exacerbation of bronchial asthma; Attack of bronchial asthma; Endogenous forms of asthma; Night attacks of asthma; Cough with bronchial asthma

Composition and release form

1 divided tablet of prolonged action contains theophylline anhydrous 100 or 300 mg; In the blister is 15 or 10 pcs., In the box 2 or 3 blisters respectively.


Mode of action - vasodilator, bronchodilating, diuretic, antispasmodic, antiallergic.

Indications of Theostat

Bronchial asthma, bronchospastic syndrome.


Hypersensitivity, epilepsy, age (up to 3 years).

Application of pregnancy and breastfeeding

At pregnancy it is appointed or nominated under strict indications. It is necessary to select a dose, control the state of the mother and fetus. In case of application at the end of pregnancy tachycardia and fetal arousal are possible.

Side effects

Dyspeptic disorders, headache, agitation, insomnia, tachycardia.


Incompatible with troleandomycin; Cimetidine, erythromycin increase the concentration of theophylline in the blood, phenobarbital, carbamazepine, phenytoin and rifampicin - reduce.

Dosage and Administration

Inside, not liquid and squeezed with water. At 10 mg / kg / day in 2 divided doses, with insufficient effect and no side effects, the dose is increased by 150 mg / day; In the period of exacerbation of bronchial asthma - up to 600 mg 2 times a day. When using large doses (9 g per day) - on the third day determine the concentration of theophylline in the plasma 4 hours after the morning intake. For children older than 3 years, the average dose is 10-16 mg / kg (maximum - 20 mg / kg) per day.


In children: stimulation, logoreia, psychosis, repeated vomiting, hyperthermia, tachycardia, fibrillation and fluttering of the ventricles of the heart, convulsions, hypotension, breathing disorders, ulceration in the digestive tract; In adults - cramps, hyperthermia, cardiac arrest. Treatment - gastric lavage, symptomatic therapy in the hospital.

Precautionary measures

Use with caution in cardiac, coronary and hepatic insufficiency, hyperthyroidism, gastroduodenal ulcer (dose adjustment is necessary). Special care is required when used in children (high sensitivity to xanthines).

Storage conditions of Theostat

In the dry place.

Keep out of the reach of children.

Shelf life of the drug Theostat

Tablets of prolonged action are divisible 100 mg - 3 years.

Prolonged action tablets divisible 300 mg - 4 years.

Do not use after the expiry date printed on the package.

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