Instruction for use: Tetracosactide (Tetracosactidum)

Chemical name:

Α- (1-24) -Corticotropin (and as acetate)

Pharmacological group

Hormones of the hypothalamus, pituitary gland, gonadotropins and their antagonists

Nosological classification (ICD-10)

J45 Asthma

Asthma physical effort, status asthmaticus, Bronchial asthma, Asthma lung flow, Bronchial asthma with obstruction of sputum discharge, Bronchial asthma heavy currents, Bronchial asthma physical effort, hypersecretory asthma, Hormone-dependent form of bronchial asthma, Relief of asthma attacks in bronchial asthma, Non-allergic asthma, nocturnal asthma, Exacerbation of asthma, Asthma attacks, Endogenous forms of asthma, Night asthma, Cough with bronchial asthma

K51 Ulcerative colitis

Colitis acute ulcerative, Colitis ulcerative, Ulcerative-necrotic colitis, Colitis ulcerative-hemorrhagic nonspecific, Colitis ulcerative and trophic, Colitis ulcerative idiopathic, Colitis ulcerative nonspecific, Nonspecific ulcerative colitis, Proctocolitis ulcers, Hemorrhagic purulent rectoxitis, Rectoccolitis ulcerative-hemorrhagic

M06.9 Other specified rheumatoid arthritis

Rheumatoid arthritis,Pain syndrome in rheumatic diseases, Pain in rheumatoid arthritis, Inflammation in rheumatoid arthritis, Degenerative forms of rheumatoid arthritis, Children's rheumatoid arthritis, Exacerbation of rheumatoid arthritis, Acute articular rheumatism, Rheumatic arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatoid arthritis of active course, Rheumatoid arthritis, Rheumatoid polyarthritis, Acute rheumatoid arthritis, Acute rheumatism

M35.9 Unspecified systemic involvement of connective tissue

Hyperplasia of connective tissue, Diffuse connective tissue disease, Collagen diseases, Collagenosis, Systemic diseases of connective tissue, Diffuse connective tissue diseases

T78.3 Angioedema

Edema Quincke, Laryngeal exacerbation with angioneurotic edema, Recurrent angioedema, Allergic edema, Recurrent swelling of Quincy

CodeCAS

16960-16-0

Pharmacology

Pharmacological action - glucocorticoid, mineralocorticoid.

Stimulates the adrenal cortex (adrenocorticotropic effect). Interacts with plasma receptors, activates adenylate cyclase, the formation of cAMP and cAMP-dependent protein kinases, and the phosphorylation of key enzymes and histones.

Indications

Diffuse diseases of connective tissue (rheumatoid arthritis, etc.), allergic diseases (bronchial asthma, angioedema), dermatoses, gastrointestinal diseases (ulcerative colitis).

Contraindications

Hypersensitivity, acute psychosis, peptic ulcer of the stomach and duodenum, heart failure, pregnancy, breast-feeding.

Side effects

Decrease in resistance to infections, mental disorders, osteoporosis, erosive-ulcerative lesions of the digestive tract, skin pigmentation.

Interaction

Reduces the effect of oral antidiabetic drugs, increases - cardiac glycosides, changes - diuretics. Ketoconazole weakens the stimulating effect on the adrenal glands.

Routes of administration

In / m (intramuscularly).

Precautions

With prolonged use of the drug, additional administration to the body of potassium is necessary.

special instructions

It is recommended to vigorously shake the ampoules before use.